ABSTRACT Anaemia is one of the most clinically encountered conditions in animals and humans. It continues to be a global public health problem, affecting both developing and developed countries with major consequences for human and animal health as well as social and economic development. The objective of this study was to develop and test a rat model for experimental studies on sub-acute blood loss anaemia. The study design was an experimental research and development protocol, made up of ...
ABSTRACT The methanolic root bark extract of Afzelia Africana was tested for antidiabetic activities in-vivo. The acute toxicity of the extract was tested in mice and the result showed that the extract 6 has low toxicity. Investigation on the phytochemical constituents of the plant extract revealed the presence of flavonoids, tannins, alkaloids, steroids and saponins. The plant extract was tested for antidiabetic activities in alloxan-induced diabetic mice at doses; 62.5 mg/kg, 125 mg/kg, 25...
ABSTRACT This study was conducted to determine the prevalence of ESBL-producing enterobacteria in chickens and cattle slaughtered at Ikpa market, Nsukka; to identify the types of ESBL enzymes harboured by the ESBL-producing bacteria isolates and to determine the antibacterial résistance phenotype and genotype of the ESBL-producing isolates. This study adopted a survey design. It was conducted at Ikpa market, Nsukka, Enugu State Nigeria. The market was purposively selected because it is a ma...
Abstract This study evaluated the use of the methanolic leaf extract of Palisota hirsuta in postsurgical wound management using different wound models in rats. It also assessed the antibacterial activity of the plant extract as well as the possible toxic effects on the liver, kidney and blood. The yield of the methanolic leaf extract of Palisota hirsuta (PHLE) was 5.98 % w/w and it was dark green, pasty in consistency with a pungent smell. In the excision wound model, PHLE at 1% and 4 % sign...
ABSTRACT This study was conducted to document the occurrence and characteristics of mycotic agents isolated from trade horses and donkeys in Obollo-Afor, Enugu State. A total of 497 horses and 65 donkeys presented for sale at Obollo-Afor horse/donkey market during the wet season (June to August 2014) and dry season (January to March 2015) were examined for skin lesions. For each horse/donkey examined, the location of skin lesion as well as the sex of the animal was recorded. Each skin lesion...
ABSTRACT The high turn-over rate and quest for white meat have given more impetus to poultry production. The need to increase production and meet the demand for poultry meat has necessitated the use of veterinary drugs, especially antimicrobials, for therapeutic, prophylactic and growth promotion purposes in poultry farming. These drugs tend to accumulate in tissues and organs as residues. The presence of drug residues in tissues above the maximum residue limit (MRL) becomes violative if wit...
ABSTRACT The methanolic root bark extract of Afzelia Africana was tested for antidiabetic activities in-vivo. The acute toxicity of the extract was tested in mice and the result showed that the extract 6 has low toxicity. Investigation on the phytochemical constituents of the plant extract revealed the presence of flavonoids, tannins, alkaloids, steroids and saponins. The plant extract was tested for antidiabetic activities in alloxan-induced diabetic mice at doses; 62.5 mg/kg, 125 mg/kg, 25...
ABSTRACT Effect of stabilizing chloroquine phosphate in a synthetic Aluminium Magnesium silicate (Nanoparticles) on the antiplasmodial activity of the drug was investigated. Mice infected with Plasmodium berghei were treated with chloroquine phosphate at 7 mg/kg, 5 mg/kg and 3 mg/kg dose levels respectively. Two subgroups at each dose level were treated with chloroquine phosphate alone and with a drug formulation of 20% chloroquine phosphate in the synthetic Aluminium Magnesium Silicate (AMS...
ABSTRACT This study was carried out to evaluate the chemical composition and bacterial load of donkey meat as well as the prevalence of verotoxigenic Escherichia coli (VTEC). The study adopted the survey and experimental designs. A questionnaire, which comprised three sections, was developed to elicit information on the demographics, source of meat, and factors that influence choice of meat consumed by the respondents. The instrument for data collection was validated by three experts. A pilo...
ABSTRACT The contractile activity of M. pruriens and the relaxatory property of C. odorata was investigated using in vitro methods in the rat. M. pruriens caused a dose-dependent increase in uterine muscle contraction with a maximum peak in amplitude with 0.57 mg/ml of the extract and an EC50 of 2.7 mg/ml. The contraction was unaffected by atropine sulphate (0.042 µmol), but abolished by isoprenaline (0.06-0.23 µmol), salbutamol (0.012-0.4 µmol) and adrenaline (16 nmol).Uterine muscle con...
ABSTRACT Prevalence and distribution of bluetongue virus (BTV) antibodies in sheep and goats in Sokoto State are reported. This study aimed to determine the prevalence of BTV antibodies and to identify the potential risk factors associated with BTV infection among sheep and goats in Sokoto State, Nigeria. A total of 368 blood samples were collected randomly from four localities in Sokoto State. The serum samples were screened for bluetongue virus (BTV) antibodies using a commercial competitiv...
dth: 0px; "> Gonadal and extragonadal sperm reserves of 12 Yankasa rams aged 18-24 months, were determined following experimental Fasciola gigantica infection over a 12 week study period. Seven out of the 12 rams serving as the infected group were orally inoculated with 800 Fasciola gigantica metacercariae while the remaining 5 rams serving as control were orally give normal saline, and monitored for 12weeks before removal of the testes by open castration. The dimensions of the testicles and ...