Research Papers/Topics in Microbiology

Controlling schistosomiasis with praziquantel: How much longer without aviable alternative?

Abstract The current approach of morbidity control of schistosomiasis, a helminth disease of poverty with considerable public health and socioeconomic impact, is based on preventive chemotherapy with praziquantel. There is a pressing need for new drugs against this disease whose control entirely depends on this single drug that has been widely used over the past 40 years. We argue that a broader anthelminthic approach supplementing praziquantel with new antischistosomals targeting different p...

Vedas and Knowledge of our Ancestors: True origin of microbiology.

India is treasure of traditional Knowledge which has been disseminated through non-institutional means from generation to generation and is, for the most part, undocumented. However, the knowledge about microbial world by Indian Rishis presented in Sanskrit Shlokas or Suktas of our traditional manuscripts such as Vedas remained unseen. Before the invention of microscope modern science had little knowledge about the microbial biodiversity which is very clearly Presented in Vedas and Gita. ...

Vedic and Ancient Knowledge: Trends towards Life Sciences and medicinal microbiology.

Vedas are considered Ultimate Source of Knowledge and the most ancient written literature of the world. All great ancient thinkers and Philosophers. From Brahma down to Jaimini opine that the Vedas are as old as the advent of man and believe that the Vedas are Revelation. The natural outcome of the. Optimistic and robust outlook, which the ancient Indians had on life, was a keen desire to live a long and healthy life of a hundred years. They advocated the theory “Prevention is better tha...

Enumeration of Most Common Microbes Responsible for Tomatoes Spoilage

Abstract This study investigated the microorganisms associated with the spoilage of tomato (Lycopersicum esculentum) obtained from two markets in Jahun town, Jahun Local Government in Jigawa State, Nigeria. A total of five species of bacteria were isolated and identified viz: Bacillus subtilis, B.aureus, Escherichia coli, Klebsiella aerogenes and Staphylococcus aureus. The most prevalent bacterial isolate was Bacillus subtilis with 24% and was found in all samples from the two markets. Klebsi...

Plasmid Profile Of Streptococcus lactis And Lactobacillus Plantarum Isolated From Ogi Encoding For Acetaldehyde In Yoghurt

Abstract An investigation was carried out on the plasmid profile of Streptococcus lactis and Lactobacillus plantanum isolated from a total of 120 samples collected from Oyingbo, a local market in Lagos State. Morphological, cultural, physiological characterization and API kits were employed to isolate and identify and treptococcus lactis and Lactobacillus plantanum. All the isolates harboured plasmids ranging from 1-7 in numbers and 3kb – 21.5 kb in sizes. Distinct plasmid patterns were...

Identification and Characterization of Lactobacillus Isolates Recovered from Locally Fermented Milk (Nunu) consumed within Lagos Metropolis

ABSTRACT This work assessed the probiotic potential of “Nunu” using Lactobacillus, a genus of Lactic acid bacteria and a major probiotic organism as the indicator. The viable Lactobacillus counts of samples purchased from six different areas within Lagos Mainland were enumerated by serial dilution and pour plating in selective media, DeMann, Rogosa and Sharpe agar (MRS). Twelve strains of Lactobacillus were randomly selected from the samples and identified by standard morphological, physi...

Fine specificity of anti-MSP119 antibodies and multiplicity of Plasmodium falciparum Merozoite Surface Protein 1 types in individuals in Nigeria with sub-microscopic infection

Abstract Background: The absence of antibodies specific for the 19 kDa C-terminal domain of merozoite surface protein 1 (MSP119) has been associated with high-density malaria parasitaemia in African populations. The hypothesis that a high prevalence and/or level of anti-MSP119 antibodies that may inhibit erythrocyte invasion would be present in apparently healthy individuals who harbour a sub-microscopic malaria infection was tested in this study. Methods: Plasma samples were collected from...

Potentials of Walnut (Tetracarpidium Conophorum Mull. Arg) Leaf and Onion (Allium Cepa Linn) Bulb Extracts as Antimicrobial Agents for Fish

Abstract The development of antibiotic-resistant pathogens due to the indiscriminate use of antibiotics has led to advocacy for the use of natural products in the treatment of fish diseases. The antimicrobial activity of methanolic and ethanolic extracts of walnut leaves and onion bulbs were evaluated against six pathogenic bacteria (Pseudomonas aeruginosa, Staphyloccocus aureus, Bacillus subtilis, Pseudomonas fluorescens, Escherichia coli, Samonella typhi) using the cup – plate method. Min...

CHANGES IN THE PROTEIN AND FIBRE COMPONENTS OF CASSAVA AND YAM PEELS AFTER SOLID STATE FERMENTATION BY ASPHRCUlIMS NIGER AND RHIZOPUS SP

ABSTRACT Dried, milled cassava and yam peels were inoculated separately with A. nigermidRhizopus sp in solid state. The changes in crude protein (CP), crude fibre (CF), neutral detergent fibre (NDF), acid detergent fibre (ADF) and hemiccllulose were evaluated til 0. 4. X, and 10 days after inoculation. At. the end of the 10th day of fermentation with A. niger the crude protein of cassava peel meal (CPM) increased from 3.5% to 7.0% while that inoculated with Rhizopus sp increased to 5.25%. Cru...

Phytochemical Screening and Microbial Inhibitory Activities of Ficus Capensi

ABSTRACT Ficus plant components have application in traditional medicine because of the myriad uses they have been subjected to. The ease of application is based on the secondary metabolites this plant contains. The challenges faced by modern medicine especially in the complete cure of microbially-associated diseases through abrupt and unpredictable genetic mutations in the presence of conventional drugs informed the investigation of the microbial inhibitory activities of the stem, root and l...

Insecticide Resistance Status Of Anopheles Gambiae Breeding In Stagnant Water Bodies In Lagos, Nigeria

ABSTRACT Anopheles gambiae, the major Afro-tropical malaria vector is resistant to pyrethroid insecticide and this is threatening the impact of malaria control efforts using insecticides. In this study, the major malaria vector species from stagnant water bodies and their susceptibility status to pyrethroid insecticide was determined in some areas of Lagos state, Nigeria. Anopheles larvae were sampled from three areas of Lagos, namely Akoka, Idiaraba and Okobaba and raised to adulthood in the...

16s rRNA Gene Sequencing: A Practical Approach To Confirming The Identity Of Food Borne Bacteria

ABSTRACT One of the main challenges for clinical practice and public health surveillance is rapid and accurate identification of food borne pathogens. In Nigeria, the use of sophisticated molecular tools for foodborne pathogens detection has not been extensively adopted. Bacterial strains isolated from food products sold in Lagos, Nigeria, were subjected to phenotypic techniques and 16S rRNA gene sequencing for specie level identification. Bacterial identification was performed using colonial...

Polymerase Chain Reaction Assay Of Ureaplasma Strains Isolated From High Vaginal Swabs, Of Women In Ibadan, Nigeria

Human Ureaplasma had one species known as Ureaplasma urealyticum but was recently seperated into 2 species

Genital ulcer diseases among HIV-infected female commercial sex workers in Ibadan, Nigeria

ABSTRACT We evaluated the prevalence and association of Genital Ulcer Diseases among HIV-1 infected female commercial sex workers in Ibadan Nigeria.


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