Research Papers/Topics in Parasitology

In Vitro And In Vivo Anti-Plasmodial Activities Of Senna Occidentalis Roots Extracts Against Plasmodium Falciparum And Plasmodium Berghei

Plasmodium is a genus of parasitic protozoa, many of which cause malaria in their host. Five species namely; P. falciparum, P. malarae, P. ovale, P. vivax and P. knowlesi cause human malaria. Malaria due to P. falciparum is one of the most severe public health problems worldwide with an annual estimated 207 million clinical episodes and 627,000 deaths. The use of conventional antimalarial drugs as treatment for malaria is greatly hindered by drug resistance exhibited by the parasite. C...

Infections With Intestinal Protozoa And Geohelminths And The Risk Factors Among Secondary School Students In Maara Sub-County, Tharaka-Nithi County, Kenya

Intestinal parasitic infections caused mainly by protozoa and helminths are most prevalent in tropical and subtropical regions of the world where adequate water and proper sanitation are lacking. Helminthiasis has been listed among the three most prevalent diseases in Tharaka-Nithi County. The residents are mainly small scale nonmechanized farmers hence there is frequent contact with the soil. Chronic parasitic infection among students negatively affects their health, nutrition, cogniti...

Fish Parasites And Fisheries Productivity In Relation To Exreme Flooding Of Lake Baringo, Kenya

Fish production is an important food contributor to the global and local economy. However, diseases including parasitic infections have been recognized as one of the limiting factors in the production of fish. The increase in fish parasites can be as a result of flooding.  The flooding of Lake Baringo that occurred in November 2011 could have caused water pollution that may have brought in parasites that could have caused fish diseases. No recent research had been carried out to i...

Effects Of Plasmodium Falciparum Infected Blood On The Midgut Proteases Of Anopheles Gambiae S.S

ABSTRACT Malaria is the leading cause of death in Africa among pregnant women and children under five years. Each year 350-500 million cases of malaria occur worldwide, and over one million people die, most of them young children in sub-Saharan Africa. In Africa, Anopheles gambiae mosquito is the main vector of Plasmodium falciparum, which causes malaria. All female Anopheles mosquitoes are usually haematophagous; they require a blood meal from a vertebrate host, either before or after ...

Prevalence Of Entamoeba Histolytica Infections Among The Children Attending Primary Schools In Kyuso Zone, Kyuso District, Kitui County, Kenya

ABSTRACTThe occurrence of Entamoeba histolytica as a human intestinal parasite is a serious problem especially in developing countries. Entamoeba histolytica frequently infest as a commensal within the human large intestines with no overt clinical manifestations. However, trophozoites can invade the colonic epithelium and produce ulcers and dysentery, a condition known as Amoebiasis. Amoebic infections in Kyuso Zone, Kyuso District are common. The ecological aspects in the area and particular...

The Impact Of Climatic Variability And Malaria Control Interventions On Malaria Parasite Prevalence And Vector Abundance In Western Kenya

ABSTRACT The World Health Organization estimated annual global malaria mortality to be at 405,000 deaths in 2018 making malaria one of the most important diseases in the world. In Kenya, malaria control measures have been put up, however, the ongoing climate change and climatic variability is proving to be a great challenge. The aim of this study was to investigate the impact of climatic variability and malaria control interventions on malaria parasite prevalence and vector abundance in...

Occurrence Of Schistosoma Mansoni And Its Transmission Risks In School Children In Schistosome Non-Endemic Kagio Area In Kirinyaga County, Kenya

ABSTRACTSchistosomiasis is a chronic parasitic disease caused by a blood fluke of the genus Schistosoma. An estimated 249 million people are infected worldwide in about 78 countries with 85% infections occurring in sub-Saharan Africa. In Kenya, an estimated 5 million people are infected with about 12 million people at risk of infection. Schistosomiasis is a major public health concern due to the morbidities caused. Kagio area borders Mwea irrigation scheme which is an endemic area with a prev...

Amoebiasis levels in relation to sanitation and personal hygiene among patients attending Kauwi and Muthale hospitals in Kitui county, Kenya

ABSTRACTEntamoeba histolytica, an intestinal protozoan parasite, is the causative agent for amoebiasis which is the third leading parasitic disease causing deaths in humans after malaria and schistosomiasis. Globally, it is responsible for 40,000 to 100,000 deaths annually. Amoebiasis is on the rise in Kitui County and is responsible for diarrheal illnesses and early deaths in children under 5 years. There is no surveillance system in Kenya to combat the disease and its real level of occurren...

Evaluation Of Malaria Infection In Relation To Age, Residence And Diagnosis Of Patients Attending Kipsamoite Dispensary, Nandi North District, Kenya

Malaria imposes a huge burden upon the health and economic development of tropical nations and has been identified as a major obstacle to sustainable development by the world’s poorest regions. Diagnosis of malaria still remains a major challenge towards effective case management more so in areas with limited diagnostic facilities and lack of access to skilled health personnel. Clinical diagnosis which is the most widely used approach has several limitations le...

Infection Rates Of Schistosoma Haematobium Among Primary School Children In Garsen Constituency, Tana River County, Kenya And The Types Of Snail Vectors

ABSTRACTSchistosomiasis, also known as bilharziases is a parasitic disease caused by blood flukes (trematodes) of the genus Schistosoma. Both urinary schistosomiasis caused by Schistosoma haematobium and intestinal schistosomiasis caused by S. mansoni occur in various regions of Kenya, including the coastal region. River Tana which flows through Garsen, offer breeding sites for Bulinus snails which are the fresh water snail vectors for S. haematobium. Despite the WHO recommending the strategy...

Prevalence Of Plasmodium Species Infection Among Primary School Children And Performance Of Malaria Rapid Diagnostic Test Kits In Baringo County, Kenya.

Malaria causes the greatest public health burden in sub-Saharan Africa where high mortality mainly occurs in children under five years of age and pregnant women. Majority of Kenyan population are at risk of malaria infection. Traditionally, malaria has been studied mainly in Western and Coastal Kenya while the rift valley especially Baringo County few malaria studies have been conducted indicating seasonal transmission. This has resulted in scanty information on actua...

Evaluating The Occurrence Of Schistosoma Haematobium And Geohelminthes Infection In Residents Of Two Villages In Msambweni District Of Coast Province, Kenya.

ABSTRACTThe presence of multiple concurrent infections, or polyparasitism, is quite common in schistosomiasis endemic areas. Msambweni District in the Coast Province of Kenya is highly endemic for Schistosoma haematobium. Previous studies showed an overall prevalence of schistosomiasis in Msambweni District at 40% to 60%. This is a prevalence way above the national prevalence of approximately 23%. There has been continued support by various agencies, including the government and non-governmen...

Safety And Efficacy Of Prosopis Juliflora Leaf Extract As A Potential Treatment Against Visceral Leishmaniasis

ABSTRACTLeishmaniasis is a major health problem in the tropics and sub-tropic regions where it is endemic. The treatment of leishmaniasis is faced with several drawbacks. Up to date there is no vaccine against leishmaniasis. The current antileishmanial drugs are associated with high resistance and relapse rate. The drugs are highly costly, toxic and have to be administered in hospitals hence not freely accessible to Leishmania infected populations. Prosopis juliflora (PJ) is a locally availab...

Evaluating Phytochemical Profiles, Molluscicidal And Schistosomicidal Activity Of Aqueous And Ethanol Extracts Of Vernonia Amygdalina And Harrisonia Abyssinica

ABSTRACTSchistosomiasis is considered one of the neglected tropical diseases caused by blood flukes. The disease kills 200,000 people annually in Sub Saharan Africa and stunts cognitive and physical growth. In Kenya, the total population requiring preventive chemotherapy in the year 2015 was estimated at 2.5 million out of which 1.8 million were school aged children. Fresh water snails of genus Biomphalaria are the intermediate hosts of S. mansoni. Chemical molluscicides used to control snail...

Prevalence Ofamoebiasis And The Factors Associated With Its Transmission Among Patients Attending Longisa County Hospital, Bomet County, Kenya

ABSTRACTAmoebiasis is a common life-threatening parasitic disease affecting 12% of the world population. It is the third leading cause of mortality due to parasitic infections worldwide, after malaria and schistosomiasis. It is estimated that about 500 million people are at risk of infection with amoebiasis yearly. In developed countries infection occurs among travelers, recent immigrants from endemic regions, homosexual males, immune-compromised persons and institutionalized individuals. In ...


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