ABSTRACT Malaria is devastating diseases afflicting humans, in Kenya; the disease is endemic in areas around Lake Victoria and along the southern coast. Untreated malaria in school children, result in anaemia, reduced ability to concentrate and learn in school and if fallen sick may lead to school absenteeism. Insecticide treated nets (ITN) have been shown to provide significant protection against Plasmodium infection. Available data show that the overall prevalence of Plasmodium and anaemia...
ABSTRACT There are arthropod-borne disease outbreaks as a result of pathogen influx including arboviruses which are transmitted by strains of Aedes species that occur periodically in varying spots in Kenya. However, there has been paucity of documented information on the epidemiology of Aedes mosquitoes involved in transmission of different strains of viruses. This cross sectional study determined spatial and temporal distribution of Aedes mosquitoes, Dengue and Chikungunya viruses, and...
ABSTRACT Malaria is an infectious disease of humans and other animals caused by protozoa of the genus Plasmodium and is transmitted mainly through bites of infected female Anopheles mosquitoes. The main species causing the disease in humans include Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, Plasmodium vivax and Plasmodium knowlesi. The disease results from multiplication of Plasmodium parasites within red blood cells, causing symptoms that typically include fever, headache,...
ABSTRACT Plasmodium is protozoa from the Apicomplexa phylum which causes malaria. In the tropics and sub-tropics, approximately 3.3 billion people are at risk. Artemisinin Combination Therapy (ACT), the current prime treatment, has been reported to have a possible emergence of resistance. This is a major obstacle that contributes to high mortality. Drug repurposing offers an appealing alternative to de novo drug development. Although astemizole and methylene blue have been reported to have an...
ABSTRACT Human African Trypanosomiasis (HAT) is a protozoal disease that is caused by the extracellular parasite and also transmitted by vector known as tsetse fly that belong to genus Glossina. HAT commonly known as Sleeping sickness is a tropical disease that is neglected, historically endemic among 36 countries of Africa in sub-Saharan. In the last decade, WHO reports shows a tremendous decline in cases due to collaboration from both national and international efforts. Early diagnosis espe...
ABSTRACT Solanum acueastrum Dunal. plant (Solanaceae family), growing in most parts of tropical Africa down to South Africa, has been shown to have some chemotherapeutic value. The fruit and leaf of S. aculeastrum is used for treating various diseases like jigger wounds, swelling joints in fingers, bronchitis, enlarged spleen, rheumatism, gangrene, gonorrhea, and other inflammatory-related ailments. Scientific studies conducted in S. Africa have also validated that S. aculeastrum fruit extrac...
ABSTRACT Insecticide-treated nets (ITNs) for personal protection against mosquito bites have proven to be practical, highly effective, and cost effective intervention against malaria infection. Bungoma South District records malaria as the most frequently diagnosed condition in outpatients at health facilities and is the principal cause of death at the district hospital. Despite the report that ITNs have high impact on reduction of vectors of malaria, sporozoite rates, morbidity and mortality...
ABSTRACT Malaria, a disease caused by Plasmodium species is currently the main cause of human sickness and death in the world, more so in the tropics. It mostly affects pregnant mothers and children below five years of age. The parasites develop resistance to antiplasmodial drugs and this has been a challenge in control and treatment of the disease through chemotherapy, something that necessitates the continuous search for alternative antiplasmodial agents. The use of plants to treat malaria ...
ABSTRACT Despite intensive worldwide attempt to control malaria, it remains one of the most fatal and widespread protozoan infection of mankind. About 2.4 billon people inhabit malaria prone regions which is about forty percentage of the world population. Prompt accurate, diagnosis and treatment is important to avert suffering of malaria patients. Malaria infection is a serious global challenge in the affected countries. The rapid diagnosis tests of malaria are recent diagnostic techniques wh...
Abstract The study was conducted in Khartoum hospital during the period from October 2013 to September 2013. The aim of the study was to determine the frequency of infection by E.histolytica and G.lamblia in Khartoum hospital .Hundred patients were included in this study, 61 were males and 39 were females with different age ranging from 1-70 years. Stool samples were collected from all patients. The stool samples were examined to detect the cyst of E.histolytica and G.lamblia by using wet pr...
Abstract This study was conducted on schools children in Al-kalakla locality in Khartoum state. In this study, 134 stool samples were collected from students (67 males and 67 females). The stool samples were processed by wet preparation technique, formal ether concentration technique and saturated sugar floatation technique. The results revealed that out of the 134 stool samples collected from schools children in Al-kalakla locality in Khartoum state, 48 were found positive for gastrointesti...
AbstrAct This study was carried out in Central Blood Bank in Gadaref state to detect the infection rate of toxoplasmosis and malaria. Cross sectional study was carried out during period from May to September 2013. A total number of 100 studied population (age between 18-47 years old) were included in this study. Blood samples were taken from all subjects. Clinical and parasitological data was obtained and recorded.Thirty three out from 100 (33%) and 28 out of 100 (28%) Blood samples were fou...
Abstract Various plants products including seeds are an important source for vitamins, minerals, proteins, and energy. Predominantly they are eaten fresh and uncooked or even if it they are cooked; they are handled in un-hygienic manner that change them to a major source of intestinal infection. This study aimed to assess the parasitic contamination in roasted groundnut, nabag, and tasali sold by street venders at Khartoum state, Sudan at the period from July 2019 to January 2020. A total of...
Abstract This study was conducted in Khartoum state- Omdurman (Ombada hospital and Altohamy health center), during the period between August 2018 to April 2019. The study is case- control study, one hundred and fifty individual were enrolled in this study, (100 malaria patients and 50 individuals as controls). 5ml of blood sample was collected from each participant and investigated for malaria infection by both microscopic examination and immunochromatographic test (ICT), serum ferritin leve...
Abstract : Schistosoma haematobium infection in endemic areas varies depending on the nature and complexity of the transmission networks present. Studies of micro-geographical transmission of S. haematobium infection indicate that discrepancy in prevalence between households is associated with diverse water contact behaviors and transmission that is restricted to particular sites harboring snail intermediate hosts. Detection of variations in the transmission sources with complex transmissio...