Abstract It has been shown in epidemiological studies that malaria may play a role in the pathogenesis o f endemic Burkitt’s Lymphoma (eBL). The contribution o f m alaria to the pathogenesis o f eBL is believed to be due to the imbalances in the immune regulation during malaria infection. Studies have shown a loss o f CTL function due to a shift o f the immune responses from T h l towards Th2 T-cell function during malaria infection. This study sought to investigate the phenotypes o f perip...
ABSTRACT A study to evaluate the genetic similarities and differences among 11 specimens of cichlids and four specimens of mudcatfishes obtained from Warri river
Abstract Dracunculiasis still remains as a disease o f public health importance in Ghana, especially in the Northern, Volta and Brong-Ahafo Regions, despite over a decade o f an Eradication Programme. In this study, attempts have been made to determine the problems associated with the eradication o f Guinea worm in the Northern Region o f Ghana, and suggestions provided to overcome them. Also investigated were the longitudinal anatomical variation of the parasite, the vector species and ...
ABSTRACT In a survey of children living in South Western Nigeria . plasma levels of a nti -MSP119 antibodies were not associated with patent parasitemia. Anti -MSP1 ,9 antibody titres correlated positively with age, indicating that development of antibodies to MSP1'9 may depend on long -term exposure to parasites.
ABSTRACT Indiscriminate disposal of electronic wastes (e-wastes) in Nigeria is on the increase. The release of hazardous substances from these wastes may have harmful consequences on the environment and public health. In Nigeria, there is dearth of information on environmental contamination and genotoxicity of e-wastes, and the mechanism of genetic damage. This study was designed to investigate the level of contaminants in soil, plant and well water; potential in vivo and in vitro cytogenoto...
ABSTRACT This study assessed the serum ferritin levels in plasma samples from children (4 – 74 months old) admitted for malaria at the Adeoyo Maternity Hospital (Beere) Ibadan, Oyo State, using a sandwich-ELISA. These values were compared with malaria parasitemia, MSP-1 antibody titre and packed cell volume values previously obtained through standard methods. Statistical analyses were carried out using SPSS, Excel and Epi-Calc software. Results showed that the serum ferritin level in the po...
Abstract Background: Rapid and accurate diagnosis is necessary for the management of schistosomiasis in endemic areas. Objective: To assess the burden of urogenital schistosomiasis and the diagnostic efficiency of morbidity indicators of the disease in an endemic rural community of Nigeria. Methods: A cross-sectional school-based study was conducted. Urine samples of 487 pupils were screened microscopically for S. haematobium and tested for haematuria and proteinuria using chemical reagent...
ABSTRACT Soil samples were randomly collected from 25 different observed and suspected human communal defecation locations within Ibadan. All the soil types encountered namely, sand, sandy loam, Sandy, clay loamy, and loamy sand enhanced hookworm larval propagation. The organic matter content showed a decrease with depth. The surface layer soil samples supported hookworm larval growth while the sub soil layer with the same amount of organic matter content as the surface soil layers showed a n...
ABSTRACT Malaria transmission is seasonal with higher transmission occurring in the rainy season. The burden of malaria falls mainly on children and causes anaemia and fever. Children of school going age are affected and this leads to absence from school. Blood samples were collected from children aged 10 days to 15 years in dry and rainy seasons. Parasite densities were determined by microscopy. Malaria prevalence was higher in the rainy season than in the dry season. In the dry season, 42.4...
ABSTRACT In the absence of microscopic examination, the high prevalence of asymptomatic malaria infections and the non-specific symptoms of the disease make clinical diagnosis difficult in highly endemic areas. Data from daily medical records 0f 111 adult volunteers obtained in a 13-month longitudinal survey were analysed using Pearson's correlation to investigate the relationship between parasitaernia and clinical symptoms and to determine the predictive strength of various clinical symptoms...
ABSTRACT The life cycle, and morphometries studies of A. dispersus (Rusell), white flies were conducted in a screen house in the Department of Zoology, University of Ibadan, Ibadan. The study revealed that A. dispersus (Rusell) on cassava potted plants leaves, Manihot esculenta (Cranzt) (TMS 91934), have six stages, which include, egg first instar, second instar, third instar, pupa and adult. Trichoderma lignorum a fungal was identified as the cause of high mortality rate which occurred on t...
Abstract Background: The most common cause of anemia is a deficiency of iron; but it may also be caused by deficiencies of folates, vitamin B12 and protein. Some anemias are not caused by nutritional factors, but by congenital factors and parasitic diseases such as malaria. This study attempted to estimate the prevalence of anemia among pre-school and school- aged children in two rural areas of Odogbolu Local government area, and to determine whether its cause was nutritional or could be att...
Abstract Nigeria has a high burden of vector borne diseases such as malaria and lymphatic filariasis (LF). This study aimed to determine the species composition of mosquitoes in Ibadan, Southwest Nigeria as well as determine their role in malaria and LF transmission. Adult mosquitoes were collected by Pyrethrum Spray Catch (PSC) and identified and graded according to their abdominal conditions. The mosquitoes were dissected to determine the parity status and to check for microfilariae of Wuc...
ABSTRACT Dichlorodiphenyltrichloroethane (DDT) and deltamethrin are insecticides frequently used in malaria vector control interventions in Africa. Resistance to these insecticides has emerged in the malaria vector, Anopheles. However, the assortment of two genetic mechanisms, 2La inversion and the polymorphism of microsatellite loci, have also been associated with insecticide resistance in Anopheles populations in several countries with limited studies on these resistance mechanisms in Nige...
Abstract Metallothionein-1 (MT-1), cytochrome P450-2A (CYP2a) and other genes are involved in the detoxification of xenobiotics such as heavy metals and toxins. Changes in their expression precede overt toxic effects and can serve as a marker for exposure to pollutants. We used a mouse experimental system and quantitative reverse transcription polymerase chain reaction to determine changes in gene expression and the direction of change, in response to exposure to lead acetate (LA) and waste ...