The objective of this research was to investigate the anti-hyperglyceamic properties of the aqueous
extract green peel of (Banana) musa acuminata 'nakitembe cultivar' in alloxan induced diabetic rats.
The extract used was obtaned from the green banana dried and phytochemical analysis and acute
toxicity study carried out.
Alloxan was used to induce diabetes in experimental albino Rats at a dose of 140mg/kg body weight.
After three days, the animals blood sugar levels was tested and those with BS above 7mmol/l were
selected for the study. One group was the normal control with normal BS levels.
Goup I was normal control treated with nonnal saline, Group II was diabetic control treated with normal
saline 2mllkg body weight. Group III and IV recieved extract at a dose of 400 and 800 mg/kg body
weight. Group V was treated with standard drug insulin at a dose of 0.03JU/kg body weight. The
animals were treated daily and BS was determined every after three days. The project was carried out for
15 days. Blood for testing BS levels was obtained from tail vein.
Results ; Phytochemical analysis revealed presence of saponins, tannins, phenols, flavonoids, cardiac
glycoside, alkaloids. steroids and terpenoids. The extract showed no signs of toxicity such as salivation,
diarrhoea, depression, stimulation, vomiting, and comma and there was no mortality observed up to a
dose of 4000mg/kg. Administration of the extract to GROUP III and GROUP IV did not show any
significant changes blood sugar levels as compared to that of GROUP V which received the standard
Conclusion; At the doses investigated, the aqueous extract of the green banana peel did not possess
;ignificant anti-hyperglycemic effect. However it contains phytochemicals which have antioxidant
Jropetiies useful in preventing complication brought about by ·glucose toxicity in diabetic patients. The
lavonoid content possess significant effect on normalization of serum creatinine level and lowering of
-a and relative weight of liver, indicating possible presence of kidney and liver protective propetiy. The
,reen banana peels have an added advantage thus diabetic patients should continue boiling the banana
rith the peels.
Edu, F (2021). Investigation of anti-hyperglyceamic properties of the aqueous extract of green peel of musa acuminata 'naj(jtembe cultivar'. Afribary.com: Retrieved June 24, 2021, from https://afribary.com/works/investigation-of-anti-hyperglyceamic-properties-of-the-aqueous-extract-of-green-peel-of-musa-acuminata-naj-jtembe-cultivar
Frontiers, Edu. "Investigation of anti-hyperglyceamic properties of the aqueous extract of green peel of musa acuminata 'naj(jtembe cultivar'" Afribary.com. Afribary.com, 10 Jun. 2021, https://afribary.com/works/investigation-of-anti-hyperglyceamic-properties-of-the-aqueous-extract-of-green-peel-of-musa-acuminata-naj-jtembe-cultivar . Accessed 24 Jun. 2021.
Frontiers, Edu. "Investigation of anti-hyperglyceamic properties of the aqueous extract of green peel of musa acuminata 'naj(jtembe cultivar'". Afribary.com, Afribary.com, 10 Jun. 2021. Web. 24 Jun. 2021. < https://afribary.com/works/investigation-of-anti-hyperglyceamic-properties-of-the-aqueous-extract-of-green-peel-of-musa-acuminata-naj-jtembe-cultivar >.
Frontiers, Edu. "Investigation of anti-hyperglyceamic properties of the aqueous extract of green peel of musa acuminata 'naj(jtembe cultivar'" Afribary.com (2021). Accessed June 24, 2021. https://afribary.com/works/investigation-of-anti-hyperglyceamic-properties-of-the-aqueous-extract-of-green-peel-of-musa-acuminata-naj-jtembe-cultivar