Search result: 11 clinical studies were found. Clinical outcomes: The results suggest efficacy of resin-infiltration technique to stop caries progression and to improve aesthetic appearance of white spot lesions (WSL). However, discomfort levels appear to be higher than with other noninvasive interventions. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical eviden...
Search result: As the topic of CPP-ACP is of high-priority a more intensive systematic literature search was conducted in order to produce this evidence sheet. 25 clinical studies were found. In-situ studies, as well as studies including ACP/casein materials not covered by the Recaldent technology, as included in the original systematic review, were not included. Clinical outcomes: The results regarding the clinical efficacy of CPP-ACP in the prevention and treatment of dental caries, i.e....
Search result: Only one clinical study was found. Clinical outcomes: The results indicate no difference in the caries preventive effect between both materials as fissure sealants in permanent teeth. The retention rate of RM-GIC in pits and fissures was higher than for conventional GIC. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in t...
Search result: 2 trials were found. Clinical outcomes: The results of the laboratory trials suggest that stannous ions have a remineralising (therapeutic) effect on dental tissue (particularly when stannous fluoride was compared to sodium fluoride). The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical...
Search result: 8 trials were found. Clinical outcomes: The results of the mainly laboratory trials suggest that stannous ions have an inhibiting effect on oral bacteria (particularly when stannous fluoride was compared to sodium fluoride). The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence ...
Search result: 13 trials were found. Clinical outcomes: The results of the mainly laboratory trials suggest that zinc has an inhibiting effect on oral bacteria. The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment ...
Search result: Only trials with low-viscosity GIC were found. The results suggest that cervical restorations placed with chemically cured GICs have good survival rates when compared to composite but are less aesthetic. Clinical outcomes: The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searche...
Search result: No clinical evidence concerning adverse effects of aluminium, barium or strontium released from glassionomer cements (GICs) were found. Clinical outcomes: A review of the relevant laboratory literature, including a conservative calculation of any potential adverse clinical effect due to aluminium content, concludes that the amount of aluminum that could be leached into the body from glass-ionomer dental fillings is well below the permitted daily dose and almost certainly too...
Search result: Three articles could be found. Clinical outcomes: Capsule mixed HVGIC (high-viscosity glass-ionomer cement) restorations appear to be superior to that of hand mixed. The quality of the existing evidence requires further assessment. The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systemati...
Search result: Two clinical controlled trials were found. Clinical outcomes: The results suggest no difference in the failure rate of GIC restorations placed after either complete or incomplete removal of infected (soft) carious dentin. The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches...
Search result: Four clinical controlled trials were found between the period of 2004 and 2015 (19.11.15). Clinical outcomes: The results show that composite resin performs less satisfactory when compared to amalgam.The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental litera...
Search result: One article, reporting on 2 clinical trials, was identified, concerning plaque pH-decrease after sucrose challenge: (a) comparison of CPP-ACP containing paste with no paste; (b) comparison of CPP-ACP containing paste with placebo. Clinical outcomes: The results show a significant reduction in plaque pH fall after sucrose challenge with CPP-ACP containing paste. The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are ...
Search result: No clinical trials or 2-arm (controlled) trials of any design (in-situ, in-vitro) could be found. Only one singlearm/longitudinal in-situ trial was identified. This trial used the test subjects as control group (without CPP-ACP). Clinical outcomes: The results of this trial showed an increase of the saliva pH in 16 out of 25 subjects after 3 weeks. A change from the initial level of pH 6.6 to the final level of around pH 7.6 was observed. The current level of clinical evidenc...
Search result: Ten clinical trials were found and traced concerning high-viscosity conventional GIC. No trials were identified comparing strontium or calcium low-viscosity conventional GIC. All identified trials compared Fuji IX for strontium and Ketac Molar for calcium based GIC. Clinical outcomes: The overall results suggest no difference between Fuji IX and Ketac Molar in the clinical outcomes of: recurrent caries, occlusal wear and colour match. Two of the 10 trials suggest a higher fa...
Search result: Three clinical trials with a laboratory component were found. Clinical outcomes: There appears to be no difference in the pulp response between conventional GIC and CaOH-cement (CaOH is considered to be the gold standard in pulp treatment due to its high tissue supporting properties. Lack of difference between C-GIC and CaOH suggest high biocompatibility of C-GIC concerning pulp tissue).The current level of clinical evidence to this topic is still limited in quantity and qua...