Research Papers/Topics in Pharmaceutics

Study On The Formulation Of Pantoprazole Microspheres And Tablets Using Mucuna pruriens Starch

ABSTRACTMicrosphere drug delivery systems are used to protect sensitive drugs from enzymatic degradation in the body, for controlled release and tissue targeting of the drug of interest. Starch and products derived from starch modification, are increasingly gaining acceptance in microsphere drug delivery. They are less expensive, non-toxic, readily available, bio-compatible and bio-degradable. The aim of the study was to formulate sustained release pantoprazole microspheres and enteric-coated...

USE OF CARICA PAPAYA SEEDS IN A SUSPENSION FOR THE TREATMENT OF INTESTINAL PARASITIC WORMS

ABSTRACTThe seeds of a tropical fruit Carica papaya have been proven to have anthelminthic activity. The main component in the seeds responsible for this activity is Benzyl isothiocyanate. It is effective against parasites such Ascaris lumbricoides, Strongyloides stercoralis, Taenia saginata and so on. The research focus on formulating an anthelminthic medicine from papaya seeds that can be gotten easily. The Carica papaya seeds were gotten from fresh papaya frui...

Toxicity Assessment of Stem Bark Extracts

Spondias mombin is depends on for various herbal remedies for the treatment of numerous health conditions. This study is to evaluate the In-vivo toxic effect of Stem bark extracts of Spondias mombin on in male and female albino rats. In-vivo  toxicity test was carried out with modified Lorke’s method. Forty two (42) male and female albino rats weighing between 120-180g were used for the sub-chronic study. The rats were divided into five groups A- D (n=12). The albino rats were divided ...

Antimicrobial, Phytochemical and Proximate Analysis of Four Nigerian Medicinal Plants on some Clinical Microorganisms

The increasing incidence of resistance to antibiotics among bacteria currently poses serious clinical and public health threat and has propelled efforts for newer alternatives to alleviate the problem. Extensive search and testing for different plants with potentials for antimicrobial properties is presently considered one of the most feasible options as substitutes to the current regimen of antimicrobials. We tested the antibacterial characteristic and the phytochemical composition of four c...

Phytochemical and Proximate

The purpose of this present study of seven Nigerian medicinal plants is to ascertain the medicinal, phytochemical and proximate constituents of the plants. The plants are .Acacia albida Del,   Anchomanes difformis Engl,   Boscia senegalensis,   Bridelia ferruginea Benth,  Ficus ingens (Miq.) Miq,  Indigofera arrecta   Hochst   and  Moringa oleifera Lam

Comparative Study of the Antibacterial and antifungal Spectrum, Phytochemi

 Piliostigma reticulatum plant found in West Africa. It is an Evergreen shrub with a twisted bole to 9 m high, with a bushy spherical canopy. Bark dark grey to brown, fibrous and corky, slash dark red. Leaves large, thick, leathery, grey-green, 6-12 cm long, Fruit large, long, straight, undulate or twisted and hard, either glabrous or sparsely pubescent, brown, indehiscent, up to 25 cm long, 5 cm wide. Alchonea laxiofolia is a Deciduous, erect to straggling shrub 7m tall. Two extracting solv...

ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL COMPOSITION OF CRUDE ETHYL ACETATE EXTRACTS OF ANISOPUS MANNI

 Anisopus mannii(Asclepiadaceae) –is a glabrous twining shrub, strong climber with greenish flower in globose, lateral umbelliform cymes it is widely used as an anti-diabetic agent in Northern and southern Nigerian traditional medicine, Studies were conducted to determine the phytochemical constituents of leaf and bark ethyl acetate extracts of Anisopus mannii and to evaluate its antimicrobial activity, using the agar well diffusion technique using standard phytochemical analysis procedure...

ANTIBACTERIAL SENSITIVITY PROFILE, ISOLATION AND IDENTIFICATI ON OF BACTERIA USING API 20E KITS

The purpose of this research work is to determine the microbiological profile of hospital solid waste dump sites, sensitivity to antibiotic and isolation and identification of the organism using API 20 E kit method of analysis. Microbiological profiling was carried out on hospital solid waste collected from State Specialist Hospital in Ikare-Akoko. The mean total aerobic counts of the bacteria isolated from the solid waste samples collected from six (6) units in the hospital were 5.0 x 104 cf...

Assessment of Antimicrobial and Phytochemical Properties of Crude Leaf and Bark Extracts of Ceiba Pentandra on Selected Clinical Isolates Found in Nigerian Teaching Hospital

AbstractCeiba pentandra is a tropical tree of order Malvales and the family Malvaceae. The basic objective of this research work is to determine the antimicrobial and phytochemical properties of Ceiba pentandra. Fresh leaves and bark of Ceiba petandra was collected at Akungba Akoko. Ceiba pentandra (leaf and bark) were prepared for extraction using ethyl acetate. The test organisms used for this research work are: Escherichia coli, Salmonella typhi, Bacillus subtilis, Kleibsiella pneumonia an...