Abstract The first aim of this dissertation was to monitor both rat and human responses to short-term perturbations in energy balance brought about through food energy restriction and refeeding, exercise training and the cessation of exercise training or surgical lipectomy. The second aim of this dissertation was to identify factors which might explain differences in food energy intake in weight-matched, weight-stable "large and small eaters". The final aim of this dissertation was to identi...
Raynauds Phenomena of the Upper Extremities with Special Reference to Sympathectomy and Regeneration of the sympathetci
ABSTRACT Extract of Ocimumgratissimum (OG) is popularly used to treat diabetes mellitus and its hypoglycaemic activity has been confirmed by in vivo studies. There is paucity of data on the effect of this extract on placenta development and birth outcome in diabetic pregnancy. This study was therefore aimed at investigating this.42 pregnant rats weighing 150-200g were used. They were divided into control and extract treated diabetic and non-diabetic groups with 6 rats in each subgroup. Extra...
ABSTRACT The worldwide prevalence of erectile dysfunction (ED) in 1995 was estimated to be 152 million males, and the figure is expected to rise to 322 million by the year 2025. The inability to achieve or sustain an erection and/or an inability to ejaculate is common among men over 40 years, where about 5% will experience ED and rates increase with age. Pomegranate (Punica granatum L.) has traditionally been believed to be of importance in male sexual disorder management. This investigation ...
ABSTRACT The thriving of the ostrich in an otherwise very harsh environment has been an intriguing question to many people. The objective of this study was to find out some of the physiological explanations to this question. Some aspects of nitrogen metabolism were studied in the as trich : Major urinary nitrogen metabolites in ostrich urine (uric acid nitrogen, urea nitrogen and ammonia nitrogen) were partitioned. Plasma urea and urinary ammonia levels were also determined using commercial k...
ABSTRACT Clinicians are becoming increasingly interested in the use of exercise training to enhance functional outcomes and improve physiological parameters after stroke. The main aim of this study was to evaluate the effects of exercise training on walking function and selected cardiovascular parameters of adult patients with stroke. Sixty-seven (67) stroke subjects comprising 36 men and 31 women participated in the study. They were randomly assigned to two exercise groups (A and B) and a co...
ABSTRACT Blood pressure is consistently higher in males compared with females from puberty onwards and men show an increased risk for hypertension compared to women. The gender disparity in cardiovascular functions and diseases has been linked to the effect of sex hormones on vascular reactivity. Although previous studies have suggested that the effect of chronic exposure to testosterone is an increase in vascular tone, it therefore implies that lack of testosterone should elicit vasorelaxat...
ABSTRACT Metabolic syndrome (MS) is rapidly increasing in prevalence worldwide and is a top risk factor for noncommunicable diseases which are among the world's biggest killer diseases. In Africa, the prevalence of MS is estimated to be between 17% and 25%. Studies have compared the prevalence of MS but yielded varied rates among the youth and adults in various countries. These variations are suggestive of the fact that MS components could be population dependent. The prevalence of MS and ass...
ABSTRACT The mechanisms by which salt causes hypertension are not conclusive. Increased sympathetic activity and systemic vascular dysfunction have both been implicated as well as mutations of the epithelial sodium channel (ENaC) that resulted in increased reabsorption of salt from the distal nephron. However, although an adrenergic overdrive has been observed in some hypertensive patients, it is not clear whether this adrenergic overdrive is the hallmark of hypertension. It has equally been...
ABSTRACT There is dearth of scientific information on the effects of Hybanthus enneaspermus (HE) and Parquetina nigrescens (PN) on female reproduction, pregnancy and its outcome. Yet, these two medicinal plants remain the first line of medicinal plants commonly used by Traditional Birth Attendants in care of women before, during and after pregnancy in South-west Nigeria. The effect of aqueous leaf extract of Hybanthus enneaspermus (HEaq) and Parquetina nigrescens (PNaq) on female reproductio...