Physiology Research Papers/Topics

Assessment of Haematological Parameters in Anti-Retroviral Therapy (Art)-Naïve HIV Positive Children in Enugu, Nigeria.

ABSTRACT The Human immunodeficiency virus (HIV) infection is one of the most important emerging infections of this century. The human immunodeficiency virus (HIV) infection causes the Acquired Immune Deficiency Syndrome (AIDS) which is a systemic disorder characterized by deficiency in cellular immune responses. Haematological complications that accompanied HIV infections have been documented to be the second most common causes of morbidity and mortality in children. The haematological compli...

Prevalence of Congenital Colour Vision Deficiency in Nigerians Living in Ugep, Cross River State

ABSTRACT Colour vision deficiency and colour blindness are synonymous terms describing poor colour discrimination by the visual senses. Congenital colour vision defects are common, x-linked inherited, non-progressive and untreatable disorders. Elsewhere, screening for these disorders are an established practice so that those affected can be advised about occupational preclusions. However, population-based study on the broader impact of colour vision defects is limited. A descriptive crosssect...

Effects of Selected Artemisinin-Based Antimalarial Combination Therapies (Acts) On Indomethacin induced Gastric Ulcers in Wistar Rats

ABSTRACT The gastric mucosa defence mechanisms are altered counteractively by 4-aminoquinoline and artemesinin derivatives, yet these drug lines constitute artemisinin based antimalarial combination therapies (ACTs). The study was aimed at determining the gastric mucosa effects of two ACTs (artemether-lumefantrine and artesunate-amodiaquine). Specifically to determine the effect of the ACTs on induced ulcer index, antioxidative activity, lipid peroxidation and histopathologies induced by indo...

Neuroprotective Mechanisms Of Garlic (Allium Sativum) In Modulation Of Hippocampus Function In Model Of Type Ii Diabetic Wist Ar Ra Ts

ABSTRACT Hippocampus functions have been reported to be affected by diabetes mellitus. Studies suggest that within diabetic rats, garlic (A.sativum) improves different forms of memory that depend on the hippocampus. However, the neuroprotective mechanisms of garlic (A.sativum) extract possibly mediated by the Na+/K+ ATPase, Ca2+ATPase and glutamine synthetase (GS) in the hippocampus of type II diabetic Wistar rats has not been fully demonstrated. Therefore, the present study determined the e...

Raynauds Phenomena of the Upper Extremities with Special Reference to Sympathectomy and Regeneration of the sympathetci

Raynauds Phenomena of the Upper Extremities with Special Reference to Sympathectomy and Regeneration of the sympathetci

Effect Of Ethanolic Extract Of Ocimum Gratissimum Leaves On Placental And Birth Weight And Early Postnatal Growth Of The Offspring Of Diabetic Pregnant Rats

ABSTRACT Extract of Ocimumgratissimum (OG) is popularly used to treat diabetes mellitus and its hypoglycaemic activity has been confirmed by in vivo studies. There is paucity of data on the effect of this extract on placenta development and birth outcome in diabetic pregnancy. This study was therefore aimed at investigating this.42 pregnant rats weighing 150-200g were used. They were divided into control and extract treated diabetic and non-diabetic groups with 6 rats in each subgroup. Extra...

Pregnancy- Induced Changes In Some Ventilatory Indices In Enugu, South East Nigeria

ABSTRACT Pregnancy is essentially a physiological process, which involves a great number of physiological changes, affecting virtually all the organ systems in the body. Literature is sparse on the changes in ventilatory function during pregnancy in our locality. The objective of this study is to establish the value of Forced Vital Capacity (FVC), Forced Expiratory Volume in one second (FEV1), FEV1/FVC ratio and Peak Expiratory Flow Rate (PEFR) during pregnancy. The study is a descriptive cro...

Market Integration And Pricing Efficiency Of Soyabeans In Benue And Enugu States, Nigeria

ABSTRACT The study analysed market integration and pricing efficiency of soyabeans in Benue and Enugu States, Nigeria. Low household demand for soyabeans makes its production and marketing less popular amongst farmers and marketers which leads to marketing inefficiency. A two-stage sampling technique was used to select 207 respondents. Secondary data comprising monthly retail prices (urban and rural) of soyabeans from 1999 to 2013 was also collected BNARDA and ENADEP. Descriptive statistics, ...

Experiences Of Children Who Have Gone Through The Foster Care Program In Zimbabwe.

ABSTRACT The research examined the experiences of children who have gone through the foster care program in Zimbabwe. Children coming into foster care would have been take away from their parents may be facing emotional, psychological and behavioural problems due to the turmoil, abuse and negligence they may have experienced as such it is critical to emphasise the healing aspect of foster care. There are certain challenges from the system which need to be addressed. This research was guided ...

Ageing in an Elderly Ghanaian Population: A Cross Sectional Study of Physiological Parameters, FOXO3A Genetic Variability And Oxidative Stress

ABSTRACT  Brief background Worldwide, the population of the elderly has tripled in the last century. Projections indicate that the global population of persons aged 60 years and over, which was 11% in 2000 will reach 22% by 2050. Ageing is a gradual process with various determinants many of which are modifiable. Functional systemic changes, together with the effect of the environment, nutrition, lifestyle and genome of a person may insidiously lead to the development of chronic age-associate...

DETERMINANTS OF ARTERIAL BLOOD PRESSURE IN URBAN GHANAIANS PLASMA RENIN ACTIVITY AND SODIUM BALANCE

ABSTRACT In the tropics, prevailing weather conditions exert a tremendous influence on fluid and electrolyte homeostasis of residents. For the tropical resident, who may have evolved an adaptive strategy to conserve sodium and water by renal and hormonal mechanisms, increases in sodium intake may cause changes that would, in the long term, lead to an increase in the arterial blood pressure. In this study, three serial protocols were followed to elucidate the significant role of sodium balance...

Effects of Cement Dust on Blood Glucose and Cholesterol Level in Male Wistar Rats

ABSTRACT This study was carried out to determine the effect of cement dust administration on blood glucose and cholesterol level in fasted male Wistar rats. Twenty four male Wistar rats weighing between 158-204g were used for this study. The animals were randomly divided into four groups comprising six rats each. Group 1 was the control group with no cement dust administered at all while Group2, 3 and 4 are the low dose (25g), medium dose (50g)and high dose (100g) cement dust administra...