Research Papers/Topics in Physiology

Effect of cigarette smoking on kidney functions

Introduction The kidneys play a major role in the control of the consistency of the internal environment. The blood passing through the kidneys is first filtrated (glomerular filtration) so that all the constituents, except blood cells and plasma proteins, go into the microtubular systems. In the kidneys the useful substances are quickly reabsorbed but unwanted substances escape filtration and are actively excreted in urine. (Krungkrai S, 2001).However, renal function tests are important...

Teratogen and physiological effects on organogenesis

A human teratogen is an agent that alters the growth or structure of the developing embryo or fetus, thereby causing birth defects. The first human teratogen identified in 1941 by an ophthalmologist, Norman Gregg, was maternal rubella infection in pregnancy, which produced a triad of defects (cataracts, heart malformations, and deafness) in the infants (Gregg, 1991).  Teratogens are environmental agents such as drugs, viruses, lack of nutrients, and physical or chemical elements tha...

MECHANISM OF DIAPEDESIS

Diapedesis is the means by which cells cross the walls of intact vessels. For those interested in assessing new methods for cancer therapy, I believe there are great strides to be accomplished if more efforts are concentrated on this phenomenon.CHAPTER ONE: INTRODUCTION 9CHAPTER   TWO:  ADVANCEMENTS   IN   DIAPEDESIS,   THE   PRECEEDING   STEPSAND HOW THEY ARE REGULATED 112.0.1 ADVANCEMENTS IN DIAPEDESIS 112.0.2 CLONING 122.0.2....

Endocrine and Neuroendocrine Factors Regulating Testicular Functions

The spermatogenic and steroidogenic functions of the testes is finely regulated by the brain (on stimulation), the master endocrine gland, and local factors produced by the testes. During intrauterine life the proliferation of primitive germ cells and the formation of the testes is carefully directed by testosterone, secreted by leydig cell on activation by human chorionic gonadotropin (HCG) released by the placenta. After birth, hormonal regulation of testes stop and the testes remain quice...

THE PHYSIOLOGICAL ROLE OF OREXIN TO THE HUMAN SYSTEM.

ABSTRACT Orexins are recently discovered neuropeptides synthesized by neurons located in the posteriolateral hypothalamus. There are about 10,000 to 20,000 of these neurons in the hypothalamus and their axons extend throughout the brain and spinal cord where their receptors are located. The word Orexin is a Greek word reflecting orexigenic (appetite stimulating) activity of hormone. There are two types of Orexi...

CONTROL OF BRAIN DEVELOPMENT, FUNCTIONAND BEHAVIOUR BY THE MICROBIOME

Humans share an intimate and life-long partnership with a myriad of resident microbial species (fungi, protists and viruses), collectively referred to as the microbiota (Sampson & Marmanian, 2015). The microbiome co-evolved with its human host (Chrobak et al., 2016) and is transferred from the mother to the baby during labor, with method of delivery, diet, drugs and medications (especially antibiotics) as the major contributing factor to the process of microbiome development in the infant...

Effect of insulin treatment on islet function

ABSTRACTInsulin treatment is the use of insulin and similar proteins to treat diseases including diabetes and its acutecomplications as an effective way of lowering blood glucose level in individuals with impaired Islet beta cellfunctions. The Islets (Island) of Langerhans are small clusters of cells scattered within the pancreas of mostvertebrates to bring about the secretion of the polypeptide hormone, Insulin, which is responsible for theevacuation of excess glucose in the blood stream whi...

HORMONAL CONTROL OF REPRODUCTION

TABLE OF CONTENTS   1.        INTRODUCTION 2.        TYPES OF ENDOCRINE GLAND 3.        REPRODUCTION AND ENDOCRINE CONTROL 4.        EFFECTS ...

The effect of insourcing or outsourcing decision on the productivity of Northern Cable Processing and Manufacturing Company (NOCACO) Kaduna.

INTRODUCTIONThe Insourcing and/or Outsourcing decision is referred to in purchasing as sourcing policy decision and it is one of the most important decision points for any organization because it has a multiple and web like effect on the life of the organization.Managers of businesses most especially manufacturing organizations faces a series of important and determining questions which must be answered correctly if the organization is to succeed in midst of competition. The Purchasing M...

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