Research Papers/Topics in Biochemistry

Serum liver enzymes profile and antioxidant status of male wistar rats following feeding with Cocos nucifera

The work was aimed at investigating the effect of Cocus nucifera on male albino rats. A number of rats were placed in groups and all groups were fed Cocus nucifera except one group, the control group. Analysis of results was done with ANOVA.

EFFECT OF SHEA BUTTER (Vitellaria paradoxa) RICHDIET ON GENTAMICIN INDUCED NEPHROTOXICITY IN RATS

Abstract The effect of Shea butter rich diet on gentamicin induced nephrotoxicity in rats was determined. Thirty (30) male and female albino rats grouped into 6 (normal, negative, positive, 10%, 20% and 30% Shea butter rich diet groups respectively) of 5 rats each were used for the study. Phytochemical analysis was carried out on the Shea butter used for this study which revealed the presence of saponin, tannin, alkaloid, terpenoid, flavonoid, and reducing sugar, while coumarin was absent. N...

COMPARATIVE ASSESSMENT OF PHYTOCHEMICAL CONTENT AND ANTIOXIDANT POTENTIAL OF Azadirachta indica AND Parquetina nigrescens LEAVES

ABSTRACTComparative assessment of the phytochemical content and antioxidant potential of Azadirachta indica (neem) and Parquetina nigrescens (bullock) is the aim of this study. In order to achieve this, both plants were harvested from the botanical garden, University of Ibadan. The leaves were removed from the stem, washed with running water to remove contaminants, oven dried at 37˚C and milled into powder.The qualitative analyses of both plants were investigated after which six selected phy...

EFFECTOF METHANOL EXTRACT OF cirtullus lanatus SEEDSON HEMATOLOGICAL PARAMETERS IN MODULATION OF DIHYDROTESTOSTERONE ESTRADIOL VELERATE INDUCED BENIGN PROSTATIC HYPERPLASIA IN MALE WISTAR RA

Citrullus lanatus is medicinal plants believed to have many agents acting in different ways for the health benefits of human. This study investigated the acute phytochemical contents and effect of the methanol extract on weight changes, relative organ weight, hematological parameters and biomarkers of prostate dysfunction. The result indicated the presence of alkaloids, terpenes, flavonoids, Reducing sugar, tannins and phenols. Acute toxicity studies showed that the extract was safe at 5000mg...

Electrolyte Content of Some Soft Drinks

AbstractSoft drinks are consumed daily in Nigeria due to their characteristic taste, palatability, affordability and thirst quenching potential. This study quantifies the amount of electrolytes of Biochemical significance in selected soft drinks sold in Port Harcourt and their pH values. The samples included six frequently consumed soft drinks; (Coke, Sprite, Fayrouz, Mountain-Dew, Fanta and Pepsi). The results showed that the samples contain relatively high amount of Sodium(Na+) ranging from...

STUDY ON PHYTOCHEMICAL SCREENING AND PROXIMATE ANALYSIS OF CENTAUREA PRAECOX Oliv and Hiern

ABSTRACTPhytochemical and proximate analyses were carried out on leafy stem and flower head extract of Centaurea praecox grown in Sokoto, using standard methods. The result of phytochemical analysis shows that the flower head contain 1.67mg/100g Alkaloid, 2.50mg/100 saponins, 5.20mg/100g flavonoid, 4.07mg/100g Steroid. The proximate analyses revealed that the flower head contain 3% moisture, 11.5% Ash, 3% crude lipid, 3.5% crude protein, 25% crude fibre and 57% carbohydrate. The mineral an...

Antioxidative Properties of Sida Coryembosa in Ethanol

In Africa traditional studies have shown that herbal medicine proves to be one of the best forms of treatment mensure to preventing or managing a disease condition. Sida coryembosa is a plant gotten from the eastern part of Nigeria Nnewe north to be precise and certain claims and attributes has been said about the plant in wound healing and a possible treatment to peptic ulcer as a result of oxidative stress. The roots, stems and leaves were used for the research. 100grams of each was weighed...

Phytochemical Constituents and in vitro antioxidant activity of the stem bark and oil extract of Allanblackia floribunda plant

ABSTRACT This study focused on the comparative study of the phytochemical constituents, in vitro antioxidant activity of the stem bark and seed oil extracts of Allanblackia floribunda. The phytochemical screening revealed that both extracts contain flavonoids, tannins, cardiac glycosides, alkaloids and saponins while terpenoids are absent in the stem bark extract but present in the seed oil extracts. However, the quantitative studies showed that proanthocyanidin, total phenol, total ...

In vitro ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL PROPERTIES OF METHANOL, ETHANOL AND HEXANE EXTRACTS OF Azadirachta indica LEAVES.

ABSTRACTAzadirachta indica, commonly known as Neem, has attracted worldwide prominence in recent years as a cynosure of modern medicine owing to its wide range of medicinal properties. This study was carried out to investigate the phytochemical properties and antioxidant activity of the multi-solvent (methanol, ethanol and hexane) extracts of the leaves of Azadirachta indica of Meliaceae family. The extracts were investigated for phytochemical constituents such as tannins, saponins, alkaloids...

Phytochemical Screening and Proximate Analysis of Aloe Vera Growing on Highland and Lowland Areas of Sokoto Metropolis

ABSTRACTPhytochemical and Proximate analyses of two samples of Aloe vera from variable habitats (highland and lowland) of Sokoto metropolis were accessed. Phytochemical and proximate compositions of highland sample were 8.16mg/100g of Saponin, 3.40mg/100g of Glycoside, 1.80mg/100g of Alkaloid and 2.50mg/100g of Anthraquinone. Proximate constituents’ analysis revealed 6% of Moisture, 10.5% of Ash, 2.5% of Crude lipid, 8.13% of Crude protein, 1% of Crude fibre and 70.57% of Carbohydrate respe...

Neuroprotective Effect of Croton Zambesicus Phenolic Extract on Synaptosomes of Rats Exposed to Environmental Toxicant

ABSTRACTExposure to environmental toxicant was known to cause neuronal disorders in humans. Hence, the present study evaluates the toxic effect of leachate (an environmental toxicant) in the synaptosomes of female rats and the reversal effect of phenolic-rich fraction from Croton zambesicus. Fifty animals were divided into five groups. Group I (Control) received 0.5ml of distilled water only, Group II (non-withdrawal) received 0.5ml of leachate for 14 weeks, Group III (withdrawal) received 0....

Effect of Hydroalcoholic Extract of Aframomum Melegueta in Diabetic Wistar Albino Rats

TITLE PAGETHE EFFECT OF HYDROALCOHOLIC EXTRACT OF AFRAMOMUM MELEGUETA ON SUPEROXIDE DISMUTASE ACTIVITY IN ALLOXAN INDUCED DIABETIC WISTAR ALBINO RATSBYEBELEME   EBENEZERNAU/ 2012474175SUBMITTED TOTHE DEPARTMENT OF APPLIED BIOCHEMISTRYFACULTY OF BIOSCIENCESIN PARTIAL FULFILMENT OF THE REQUIREMENTS FOR THE AWARD OF A BACHELOR OF SCIENCE (B.Sc) DEGREE IN APPLIED BIOCHEMISTRY.NNAMDI AZIKIWE UNIVERSITY,AWKA.AUGUST, 2016APPROVAL PAGEThis is to certify that this research project titled “ The eff...

Effect of Aquoeus and Ethanol Extracts of Dennettia Tripetala Cholesterol Levels in rats Exposed to Carbon Tetrachloride (CCl4)

TABLES OF CONTENT TITLE PAGE i CERTIFICATIONii DEDICATIONiii ACKNOWLEDGEMENTIV TABLES OF  CONTENTV ABSTRACTVI CHAPTER ONE1.0 INTRODUCTION1.1 LITERATURE REVIEW1.2 THE LIVER 1.2.1 CARBON TETRACHLORIDE 1.3.0 LIVER FUNCTION TEST1.3.1 TOTAL CHOLESTEROL1.3.6 FUNCTIONS OF THE LIVER1.6.0 LIPID PEROXIDATION1.8.2 BOTANICAL DESCRIPTION OF DENNETIA TRIPETALA1.8.3 COMMERCIAL / ECONOMIC IMPORTANCE OF DENNETTIA TRIPETALA1.8.4 PHYTOCHEMICAL CONSTITUENTS OF DENNETTIA TRIPETALA1.8.4.1 ...

EFFECTS OF CHRYSOPHYLLUM ALBIDUM VARIETIES ON SELECTED BIOCHEMICAL PARAMETERS USING ALBINO WISTAR RAT

Effect of Chrysophyllum albidum pulp varieties on biochemical parameters was investigated using albino rat model. Thirty male Albino rats were divided into five groups of six rats each. A group served as the control while four groups served as the test groups A, B, C and D. Test groups A and B were placed on 5% and 25% respectively compounded feed of  sweet Chrysophyllum albidum pulp variety while test groups C and D were respectively placed on 5% and 25% compounded feed of sour Chrys...

Immunomodulatory Potentials of Ethanolic Leaf Extract of Phyllantus amarus in Wistar Rats

Immunomodulatory Potentials of Ethanolic Leaf Extract of Phyllantus amarus in Wistar RatsAbstract  The  immunomodulatory  effect  of  the  ethanolic  leaf  extract  of  Phyllantus  amarus  on  wistar  rats  was investigated. Twenty eight (28) male animals were used for the study. The animals were divided into four (4) groups of seven (7) animals each. Group 1 was the normal control and received distilled water, an...


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