Research Papers/Topics in Biochemistry

A review on Erectile dysfunction

This review aims to give a simpler understanding of what the subject "Erectile dysfunction " entail. 

A review on DNA Barcoding and Metabarcoding

This review aims to shed more light on the concept of DNA barcoding and metabarcoding as we have only a few information on this very important subject. 

In-vitro Modification of Acetylcholinesterase activity in adult head of Zonocerus variegatus: a biomarker to effects of most chemical agents.

ABSTRACTAcetylcholinesterase(AChE) is the key cholinesterase in the body which catalyzes the breakdown of acetylcholine and some other choline esters that functions as neurotransmitter in living cell. It belongs to the carboxyl esterase (hydrolase) family of enzymes which are found mainly at the neuromuscular junction (point of contact between the nervous system and the muscles) and the chemical synapses of the cholinergic types. It functions to terminate synaptic transmission by breaki...

The organ distribution and characterization of Acetylcholinesterase in Adult African Grasshopper: Zonocerus variegatus and Zonocerus elegans.

Acetylcholinesterase (AChE) is the primary cholinesterase in the body which catalyzes the breakdown of acetylcholine and some other choline esters that functions as neurotransmitter in living cell. It belongs to the carboxyl esterase (hydrolase) family of enzymes which are found mainly at the neuromuscular junction (point of contact between the central nervous system and the muscles) and the chemical synapses of the cholinergic types. It functions to terminate synaptic transmission by ...

Student industrial work experience report at Nigerian Bottling Company, Asejire

 ABSTRACTThe students industrial work experience scheme (SIWES) is a skill impacting program designed to expose and prepare students of universities and other tertiary institutions for the industrial work situation that may be encountered after school. My SIWES program was undertaken at Nigeria Bottling Company limited, Asejire plant, Ibadan; a company that deals with the manufacturing of non-alcoholic beverage products such as Coca-Cola, limca, Fanta orange etc. The company has vario...

Inhibition of mitochondria pyruvate carrier- an approach to attenuating neurodegeneration

ABSTRACT Neurodegeneration is defined as the progressive loss of structure or function of neurons in the body. Different forms of neurodegenerative disease include Parkinson disease, Alzheimer disease, multiple sclerosis, Huntington’s disease, and they are caused by different mechanism such as inflammation, mitochondria dysfunction, excitotoxicity etc. Insulin sensitizers have been discovered by researchers in managing Neurodegeneration and the main one used are the thiazolidinedi...

Comparative biochemical effect ofoleanolic acid and rutin on acute kidney injury in wistar rats

ABSTRACTThe inability of an organism to efficiently remove excess waste from the body have been a major issues attached to acute kidney injury (AKI) which is the most common cause of organ dysfunction. Oleanolic acid and rutin which are from the families of saponin and flavonoid respectively have been discovered to possess certain biological activities such as anti-oxidant, anti-inflammation, anti-viral and nephroprotective activities that can help in therapeutic management of acute k...

A review on the Pathogenesis of Diabetes mellitus

The article gives a brief overview of what Diabetes mellitus is, its type and pathogenesis. It's aimed at enlightening people about this disorder. 

COMPARATIVE STUDY ON THE PHYTOCHEMICAL ANALYSES, ANTIOXIDANT ACTIVITIES AND PROXIMATE ANALYSES OF NESCAFE CAFFEINATED, DECAFFEINATED AND LIVEN ALKALINE COFFEE

ABSTRACTThe consumption of the popular beverage coffee, increases day by day. However, upcoming brands of coffee with health benefits made by claims of the product ignites curiosity in the components of the coffee. The current study deals with the phytochemical analysis, antioxidant capacity and proximate analysis of Liven Alkaline Coffee, Nescafe Caffeinated and Nescafe Decaffeinated coffee performed using standard procedures. The phytochemical analysis revealed higher contents of carbohydra...

The Toxicological Effects of Cypermethrin Administration on the Liver, Kidney, Brain and Bone Marrow of Female Rats and the Possible Ameliorative Effects of the Methalonic Leaf Extract of Jat

TABLE OF CONTENTSContents pagesCover page iDeclaration iiCertification iiiDedication ivAcknowledgement vAbstract viTable of content List of FiguresList of PlatesList of TablesCHAPTER ONEItroduction 11.1 Justification 31.2 Objectives 41.3 AimCHAPTER TWOLiterature Review2.1 Pesticide2.1.1 Uses of pesticides2.1.2 Types of Pesticides2.1.3 Cypermethrin2.1.3.1 Mechanism of Action of Cypermet...

Herbal treatment of scorpion envenomation: Plant extracts inhibited Opisthacanthus capensis venom phospholipase A2 activity

Abstract: The inhibitory effects of Momordica charantia linn, Isoberlinia doka, Terminalia avicennioides, Tamarindus indica and Crotalaria retusa L aqueous leaves extracts on Opisthacanthus capensis (Black creeping scorpion) venom phospholipase A2 (PLA2 ) activity was investigated. The enzyme from O. capensis venom had a pH and temperature optima of 5 and 60˚C respectively with an activation energy of 5.20 Kcal/mol. Different concentrations (4mg, 6mg and 8mg/ml) of Isoberlinia doka and M...

GROUP 7 PATHOGENESIS OF HIV INFECTION

The introduction of combined therapy has been an important breakthrough in the treatment of HIV infection, however for proper eradication, HIV pathogenesis has to be understood. Despite treatment with combinatorial therapies, a functional cure approach would be very effective in suppressing viraemic load in the host to such low levels that the immune system would be able to control the infection without the need for antiretroviral therapy, neither inflicting harm upon the host nor trans...

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To test the effect of Nauclea latifolia fruit on a diabetic rats. This was meant to see if the fruit has the ability to reduce blood sugar level. 

Serum Liver Enzymes Profile and Antioxidant Status of Male Wistar Rats Following Feeding with Cocos Nucifera

The work was aimed at investigating the effect of Cocus nucifera on male albino rats. A number of rats were placed in groups and all groups were fed Cocus nucifera except one group, the control group. Analysis of results was done with ANOVA.

SPECTROPHOTOMETRIC ANALYSIS OF ALPHA AMYLASE LEVELS AT STAGES IN THE RIPENING OF MUSA SPECIES

Alpha-amylases are starch degrading enzymes and their activities have been found to be the major change that occurs in the ripening of bananas and plantains. This study was designed to basically develop a simple spectrophotometric method to monitor some of the biochemical processes involved in the ripening of Giant horned plantain (Apantu), French horned plantain (Apem) and local banana (Abibifo mpua).The pericarp from five ripening stages was collected and alpha amylases were extracte...


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