Abstract The nasopharyngeal carriage rate of Neisseria meningitides among 639 school children
ABSTRACT The study was conducted to investigate the antibacterial activities of stem and leaves from Terminalia sericea and the live and dead bark from Combretum imberbe. The aqueous and organic crude extracts of the two plants were tested on Gram-negative bacteria Escherichia coli, Shigella sonnei, Serratia marcescens, Helicobacter pylori and Gram-positive bacteria Enterococcus faecalis, Staphylococcus aureus and Clostridium perfringens using the disk diffusion method. All the crude extracts...
ABSTRACT The study was conducted to investigate the antibacterial activities of stem and leaves from Terminalia sericea and the live and dead bark from Combretum imberbe. The aqueous and organic crude extracts of the two plants were tested on Gram-negative bacteria Escherichia coli, Shigella sonnei, Serratia marcescens, Helicobacter pylori and Gram-positive bacteria Enterococcus faecalis, Staphylococcus aureus and Clostridium perfringens using the disk diffusion method. All the crude extracts...
ABSTRACT Microbiota associated with beef biltong has not been assessed in Namibia and there is limited data in the literature describing the presence and role of lactic acid bacteria (LAB) in biltong products which is involved in the transformation of many aroma and flavour compounds and therefore, the quality of the final product. The aims of this study were to document the steps involved in beef biltong production, determine the physicochemical parameters that may influence microbial growth...
ABSTRACT From 2007 to 2011 HIV-positive pregnant women in Ghana, were given a combination of Zidovudine and Lamivudine as prophylaxis during pregnancy and a single dose of Nevirapine upon the onset of labour towards the prevention of mother to child transmission (PMTCT) of HIV. Since these women were subsequently given the same antiretrovirals (ARVs) to manage their HIV infection, there was, therefore, the need to determine the HIV-1 drug resistance profiles in such patients in Ghana. This s...
ABSTRACT The resurgence of lymphatic filariasis (LF) infection after several rounds of Mass Drug Administration (MDA) has been the main reason behind constant monitoring of treatment. The MDA is designed to interrupt transmission by reducing microfilaraemia in a community to a threshold that local vectors may not be able to pick up microfilariae (MF) during a blood meal. The current study has been carried out to determine whether transmission had actually been interrupted following stoppage o...
ABSTRACT Molecular studies of ESβL-producing bacteria isolated from clinical samples was determined as well as the effects of medicinal plants on the isolates. The study was conducted from September 2013 to September 2015. A total of 480 bacterial isolates (250 from urine, 110 from wound swab & 120 from HVS & US) were used. The knowledge, attitude and practices (KAP) of health workers in Imo State towards multiple antibiotic resistant bacterial isolates and extended spectrum beta-lacta...
ABSTRACT Background: Wound infections mostly caused by Pseudomonas are on the increase in hospitals in Ghana. Most of these infected wounds are very difficult to treat with available antibiotics. This failure of treatment has resulted in increased need for healthcare, undue financial burden on both hospitals and patients and finally death of many of these patients. This has become a source of worry for both patients and healthcare providers in Ghana. General Aim: The main aim of this study w...
Abstract Mushrooms are considered as one of the notable functional foods for human consumption that have been cultivated and gathered for hundreds of years. The usage of mushrooms has expanded to a wide extent not only as food but also in the area of pharmaceuticals and nutraceuticals. In particular, mushrooms have been appreciated and consumed for both their nutritional value and medicinal properties. Bioactive molecules, particularly polysaccharides (PS) from mushrooms have been the subject...
Abstract As an initial step towards characterisation of the molecular processes that define the phenotype of the mycobacterial stationary phase, the effect of growth phase of Mycobacterium smegmatis on total protein synthesis and on the heat shock response was investigated. De novo protein synthesis was monitored by labelling with 35 [S]methionine and the protein expression profiles analysed using one- and/two-dimensional polyacrylamide gel electrophoresis , autoradiography , and/or immunoblo...
ABSTRACT Methicillin-resistant staphylococcus (MRS) infections are of global concern in healthcare institutions and community settings with significant morbidity and mortality due to multidrug resistance challenges. In Nigeria, most methicillin resistance detection was based on phenotypic method with scanty reports on molecular characterisation of MRS. In this study, molecular techniques were used to determine the presence of methicillin resistant gene (mecA) with its associated resistance de...
ABSTRACT Methicillin-resistant staphylococcus (MRS) infections are of global concern in healthcare institutions and community settings with significant morbidity and mortality due to multidrug resistance challenges. In Nigeria, most methicillin resistance detection was based on phenotypic method with scanty reports on molecular characterisation of MRS. In this study, molecular techniques were used to determine the presence of methicillin resistant gene (mecA) with its associated resistance de...
A B S T R A C T The physiological activities of Bacillus species that ferment African locust bean (Parkia biqlobosa (Jacq.) BenthJ to produce ' iru1 were investigated. The strains studied belong to the B. subtillis group and Were designated BS1 , BS2, BS3, BLl, BL2, BL4 and BP2. These seven strains showed significant differences (at c* = 0.05) in gtowth and extracellular proteinases production. The following (defecending) Order was obtained for the growth of the organisms in liquid medium: BS...