Formulation factors affecting the binding properties of Chinese yam ( Dioscorea oppositifolia) and corn starches

Abstract

Objective; The quantitative effects of formulation and processing variables affecting the binding properties of Chinese yam starch ( Dioscorea oppositifolia) in chloroquine phosphate tablet formulations have been investigated in comparison with com starch using a 23 factorial experimental design. Methods: Chinese yam starch, representing the "low " level, and com starch, representing the "high" level were used as binders at concentrations of 2. 5 % w /w and 10 % w /w in chloroquine phosphate tablet formulations. The mechanical properties of the tablets, measured by the tensile strength ( T ) and brittle fracture index ( BFI) as well as the release properties measured by the disintegration time (D T ) and dissolution time ( t g0- time for 80 % drug release) , were used as assessment parameters. 

Subscribe to access this work and thousands more
Overall Rating

0

5 Star
(0)
4 Star
(0)
3 Star
(0)
2 Star
(0)
1 Star
(0)
APA

Okunlola, A & Odeku, O (2021). Formulation factors affecting the binding properties of Chinese yam ( Dioscorea oppositifolia) and corn starches. Afribary. Retrieved from https://afribary.com/works/formulation-factors-affecting-the-binding-properties-of-chinese-yam-dioscorea-oppositifolia-and-corn-starches

MLA 8th

Okunlola, Adenike and Oluwatoyin Odeku "Formulation factors affecting the binding properties of Chinese yam ( Dioscorea oppositifolia) and corn starches" Afribary. Afribary, 13 Mar. 2021, https://afribary.com/works/formulation-factors-affecting-the-binding-properties-of-chinese-yam-dioscorea-oppositifolia-and-corn-starches. Accessed 22 May. 2024.

MLA7

Okunlola, Adenike, Oluwatoyin Odeku . "Formulation factors affecting the binding properties of Chinese yam ( Dioscorea oppositifolia) and corn starches". Afribary, Afribary, 13 Mar. 2021. Web. 22 May. 2024. < https://afribary.com/works/formulation-factors-affecting-the-binding-properties-of-chinese-yam-dioscorea-oppositifolia-and-corn-starches >.

Chicago

Okunlola, Adenike and Odeku, Oluwatoyin . "Formulation factors affecting the binding properties of Chinese yam ( Dioscorea oppositifolia) and corn starches" Afribary (2021). Accessed May 22, 2024. https://afribary.com/works/formulation-factors-affecting-the-binding-properties-of-chinese-yam-dioscorea-oppositifolia-and-corn-starches