This study is aimed at evaluating the
ameliorative effect of Parkia biglobosa against
egg-yolk induced hypertension. In order to
achieve this, 30 Wistar rats were divided into
three groups of 10 each. Rats in group A
received normal feed diet and they served as the
control group while those in groups B and C
received a special prepared egg feed diet (24 egg
yolk mixed with 1 kg of normal rat diet).
Animals in group C were administered
400mg/kg body weight of P. biglobosa extract
simultaneously with the feeding. The animals
were fed orally for 21 consecutive days and had
access to drinking water ad libitum. Blood
pressure of each of these groups was determined
at day 0, 7, 14 and 21 respectively using
standard methods. A significant increase was
observed in the blood pressure of animals fed
with egg-yolk formulated diet without P.
biglobosa treatment when compared with those
fed with egg-yolk formulated diet and treated
with P. biglobosa extract and control group
respectively at P<0.05. However, this effect was
neutralized when animals fed with egg-yolk
formulated diet and treated with P. biglobosa
extract were compared with those in the control
group. With results from this study, P. biglobosa
possesses antihypertensive properties. Therefore,
its consumption especially by people above 50
years of age is highly recommended.
Airaodion, A. & Ogbuagu, E (2020). Ameliorative Effect of Parkia biglobosa (African Locust Bean) against Egg Yolk-Induced Hypertension. Afribary. Retrieved from https://afribary.com/works/ameliorative-effect-of-parkia-biglobosa-african-locust-bean-against-egg-yolk-induced-hypertension
Airaodion, Augustine, and Emmanuel Ogbuagu "Ameliorative Effect of Parkia biglobosa (African Locust Bean) against Egg Yolk-Induced Hypertension" Afribary. Afribary, 26 Jun. 2020, https://afribary.com/works/ameliorative-effect-of-parkia-biglobosa-african-locust-bean-against-egg-yolk-induced-hypertension. Accessed 27 Jul. 2021.
Airaodion, Augustine, and Emmanuel Ogbuagu . "Ameliorative Effect of Parkia biglobosa (African Locust Bean) against Egg Yolk-Induced Hypertension". Afribary, Afribary, 26 Jun. 2020. Web. 27 Jul. 2021. < https://afribary.com/works/ameliorative-effect-of-parkia-biglobosa-african-locust-bean-against-egg-yolk-induced-hypertension >.
Airaodion, Augustine and Ogbuagu, Emmanuel . "Ameliorative Effect of Parkia biglobosa (African Locust Bean) against Egg Yolk-Induced Hypertension" Afribary (2020). Accessed July 27, 2021. https://afribary.com/works/ameliorative-effect-of-parkia-biglobosa-african-locust-bean-against-egg-yolk-induced-hypertension