Effect of Common Household Insecticides Used in Nigeria on Rat Male Reproductive Hormones
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Background: The use of household insecticides for the eradication of insects especially mosquitoes
in Nigeria is increasing. These insecticides are used without consideration of their adverse effect on
human health.
Aim: This study was aimed at accessing the effect of common household insecticides used in
Nigeria on male reproductive hormones of Wistar rats.
Methodology: Thirty male Wistar rats were divided into five groups of six each and kept in different
rooms. Rats in group 1 were exposed to Rambo, those in group 2 were exposed to Mortein, those in
group 3 were exposed to Raid, those in group 4 were exposed to Baygon while those in group 5
were not exposed to any insecticide and served as the control group. The exposure was done twice
a day via inhalation route. Throughout the experiment, animals were fed ad libitum with standard feed and drinking water. After twenty-one days of exposure, they were sacrificed after an overnight
stimulating hormone (FSH), luteinizing hormone (LH), and testosterone levels were determined
using enzyme-linked immunosorbent assay (ELISA).
Results: Results showed that insecticides caused an increase in FSH but decrease in LH and
testosterone levels significantly when compared to those in control animals at P<0.05.
Conclusion: The results indicate that prolonged exposure to common household insecticides used
in Nigeria has direct effects on FSH, LH and testosterone levels and may reduce fertility in rats.
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Augustine, A (2020). Effect of Common Household Insecticides Used in Nigeria on Rat Male Reproductive Hormones. Afribary.com: Retrieved March 03, 2021, from https://afribary.com/works/effect-of-common-household-insecticides-used-in-nigeria-on-rat-male-reproductive-hormones
Airaodion, Augustine. "Effect of Common Household Insecticides Used in Nigeria on Rat Male Reproductive Hormones" Afribary.com. Afribary.com, 26 Jun. 2020, https://afribary.com/works/effect-of-common-household-insecticides-used-in-nigeria-on-rat-male-reproductive-hormones . Accessed 03 Mar. 2021.
Airaodion, Augustine. "Effect of Common Household Insecticides Used in Nigeria on Rat Male Reproductive Hormones". Afribary.com, Afribary.com, 26 Jun. 2020. Web. 03 Mar. 2021. < https://afribary.com/works/effect-of-common-household-insecticides-used-in-nigeria-on-rat-male-reproductive-hormones >.
Airaodion, Augustine. "Effect of Common Household Insecticides Used in Nigeria on Rat Male Reproductive Hormones" Afribary.com (2020). Accessed March 03, 2021. https://afribary.com/works/effect-of-common-household-insecticides-used-in-nigeria-on-rat-male-reproductive-hormones