Evaluation of Moringa oleifera Leaf Potential in the Prevention of Peptic Ulcer in Wistar Rats

Augustine Airaodion 6 PAGES (3560 WORDS) Article
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This study is aimed at investigating the potential of
aqueous extract of Moringa oleifera leaf in the
prevention of indomethacin-induced ulcer. To
achieve this, thirty adult male rats of body weight
between 150 and 200g were divided into six groups
of five rats each. Group I was treated with 0.8mg/ml
of Omeprazole for seven days. Group II was treated
with a solution of 0.8 g/ml Moringa oleifera leaf for
seven days, while group III received distilled water
for seven days. This group served as the control
group. Groups IV, V and VI were treated similarly as
groups I, II and III respectively but were treated for
fourteen days. Gastric ulceration was induced in the
rats by the administration of 50 mg/kg indomethacin
after pre-treatment with distilled water, omeprazole
and Moringa oleifera leaf for 7 and 14 days
respectively. Significant ulcer inhibition was
produced in the groups treated with M. oleifera and
Omeprazole when compared with control groups at
p<0.05, but omeprazole-treated group showed
greater ulcer inhibition (72.60 % and 74.29 %) when
compared with the Moringa oleifera leaf-treated
groups (53.43% and 57.58%) after 7 and 14 days
respectively. This study showed that M. oleifera leaf
possesses anti-ulcerogenic properties and can be
used as herbal remedy for the prevention of peptic
ulcers.
  

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APA

Augustine, A (2019). Evaluation of Moringa oleifera Leaf Potential in the Prevention of Peptic Ulcer in Wistar Rats. Afribary.com: Retrieved February 25, 2021, from https://afribary.com/works/evaluation-of-moringa-oleifera-leaf-potential-in-the-prevention-of-peptic-ulcer-in-wistar-rats

MLA 8th

Airaodion, Augustine. "Evaluation of Moringa oleifera Leaf Potential in the Prevention of Peptic Ulcer in Wistar Rats" Afribary.com. Afribary.com, 09 Apr. 2019, https://afribary.com/works/evaluation-of-moringa-oleifera-leaf-potential-in-the-prevention-of-peptic-ulcer-in-wistar-rats . Accessed 25 Feb. 2021.

MLA7

Airaodion, Augustine. "Evaluation of Moringa oleifera Leaf Potential in the Prevention of Peptic Ulcer in Wistar Rats". Afribary.com, Afribary.com, 09 Apr. 2019. Web. 25 Feb. 2021. < https://afribary.com/works/evaluation-of-moringa-oleifera-leaf-potential-in-the-prevention-of-peptic-ulcer-in-wistar-rats >.

Chicago

Airaodion, Augustine. "Evaluation of Moringa oleifera Leaf Potential in the Prevention of Peptic Ulcer in Wistar Rats" Afribary.com (2019). Accessed February 25, 2021. https://afribary.com/works/evaluation-of-moringa-oleifera-leaf-potential-in-the-prevention-of-peptic-ulcer-in-wistar-rats