Research Papers/Topics in Pediatrics

Prevalence, Risk Factors And Immediate Outcome Of Acute Kidney Injury In Critically Ill Children Admitted At Benjamin Mkapa (Bmh) And Dodoma Regional Referral Hospitals (Drrh)

ABSTRACT Background: Acute kidney injury (AKI) is increasingly becoming a global health concern and accounts for about 1.4 million deaths worldwide. Critical illness is commonly accompanied with variable degree of acute kidney injury. However, the true burden of AKI in terms of its magnitude, associated risk factors and outcome among critically ill children in Tanzania, is unknown due to limited Data. Objectives: This study was done to determine the prevalence, risk factors and the imme...

An 8-Year Review Of Major Congenital Abnormalities In A Tertiary Hospital In Lagos, Nigeria

Abstract: Background: Congenital abnormalities are defects present at birth and are increasingly becoming an important cause of neonatal mortality. They can also result in disability in majority of the survivors. Objective: To describe the pattern and outcome of major congenital abnormalities (MCA) in a tertiary hospital in Lagos, Nigeria. Methods: The labour ward and labour ward theatre delivery records and admission records of the in-born ward of the neonatal unit of a tertiary h...

Effects Of Hydroxyurea Utilization On Incidence Of Disease Related Complications Among Children With Sickle Cell Disease In Dodoma

ABSTRACTBackgroundEarly initiation of comprehensive sickle cell disease (SCD) care with interventions such as hydroxyurea (HU) and transfusion programs have significantly been related to reduced morbidity and mortality among children with SCD. Despite these proved benefits, utilization of hydroxyurea for control of SCD related complications among children with this condition in low-and middle-income countries remains low.ObjectiveTo determine the effect of Hydroxyurea Utilization on incidence...

Prevalence, Bacterial Aetiology, Antibiotic Sensitivity And Predictors Of Urinary Tract Infection Among Children With Cerebral Palsy In Dodoma City, Tanzania

ABSTRACT Background: Children with the cerebral palsy present with lower urinary tract dysfunctions and poor personal hygiene which increases their risk for UTI. As a common infectious cause of morbidity in childhood, UTI may lead to renal scarring, and subsequently hypertension and end-stage kidney disease if it is not appropriately diagnosed and promptly treated. Objective: The study aimed to determine the prevalence, bacterial isolates, antibiotic sensitivity, and predictors of UTI ...

Perfomance Of Tuberculosis Scoring Chart In Diagnosis Of Tuberculosis In Children Living With Hiv In Dodoma Municipal.

ABSTRACT Background: Tuberculosis is the most common opportunistic infection and the major cause of deaths among HIV and AIDS patients. Data reports highest prevalence of TB and HIV infection in sub Saharan Africa. Mycobacterium culture is the gold standard test for diagnosis of tuberculosis though not widely available, takes longer to get results and cannot help in management of patients hence clinical or scoring system is widely used to aid in diagnosis and management of TB in childr...

Prevalence And Factors Associated With Virological Treatment Failure Among Children And Adolescents On Antiretroviral Therapy Attending Care And Treatment Clinicin Dodoma Municipal

ABSTRACTINTRODUCTION: With the antiretroviral therapy treat-all protocol among HIV-infected children and adolescents, monitoring of virological treatment failure and assessing the factors associated with virological treatment failure is mandatory in reducing morbidity, mortality and improving quality of life. This study aimed at determining prevalence and factors associated with virological treatment failure among children and adolescents on antiretroviral therapy.METHODS: Cross-sectional fac...

Postnatal Mothers’ Competence On Kangaroo Mother Care And Its Associated Health Outcomes Of Preterm Babies In Central Zone Tanzania: Analytical Crosssection Study

ABSTRACT Background: There is slower progress on decreasing preterm deaths despite of essential newborn care intervention in Tanzania. About 24% of neonatal deaths in Tanzania occur due to prematurity related complications. The competence regarding Kangaroo Mother Care (KMC) among postnatal mothers and associated health outcomes of preterm babies in central zone is unknown. Therefore the study was aimed to assess competence of postnatal mothers on Kangaroo Mother Care (KMC) and health ...

Prevalence And Factors Associated With Urinary Tract Infections Among Febrile Children Admitted At Dodoma Regional Referral Hospital

ABSTRACT Background: Urinary Tract Infection is among the most common febrile illness affecting 150 million people worldwide. The etiology of urinary tract infection can vary from one place to another due to significant geographical variations. Paucity of information exists with regard to UTI, in terms of the prevalence, etiologies, clinical manifestation and antibiotic susceptibility in Dodoma region. The aim of this study was to determine the prevalence, aetiology, antibiotic sensitiv...

Association Between Exclusive Breastfeeding With Pneumonia And Diarrhoea, Among Infants Aged 0 To 6 Months Born To Women From Pastoralists And Hunters Community In Manyara Region, Tanzania

ABSTRACTBACKGROUND: Pneumonia and Diarrhea are the most common childhoodillnesses and are the leading cause of high childhood morbidity and mortality inManyara Region. EBF is known to be able to protect infants against these illnesses,however not much is known about the breastfeeding practices in Manyara Regionand how much it contributes to pneumonia and diarrhea.Objective: This study aimed at determining the association between EBF withpneumonia and diarrhoea among infants aged 0 to 6 months...

Determinants Of Glycemic Control Behaviour Among Caregivers Of Children With Diabetes Mellitus In Zanzibar

ABSTRACTBackground: Type 1 diabetes mellitus (T1DM) is a rapid growing public health problem in Zanzibar, Tanzania and Africa as well. Its long term complication is serous for both patients and family and may result to considerable burden to health care system. Caregiver’s adequate knowledge on glycemic control and caregiver who have diabetes care experience of 4 to 8 years have been found to be associated with poor glycemic control among children, however these have not been adequate explo...

Determinants Of Health Care Seeking Behavior Among Caregivers Of Children Under Five Years With Childhood Illnesses In Kilimanjaro Region: Community Based Cross –Sectional Study

ABSTRACT Background: The problem of healthcare-seeking behaviors is inadequate all over the world particularly in low and middle-income countries. Poor health-seeking behavior is reported to result in the delay in seeking appropriate care and increase the risk of morbidity and death in children. Despite all health consequences resulted from poor health-seeking behavior, the factors influencing it were unclear yet. Objective: The aim of this study was to examine the determinants of healthcare-...

Effect Of Orphan Institutionalization On Child Deprivation, Child Maltriatment, And Quality Of Life Among The Orphans In Zanzibar: A Cross-Sectional Study

ABSTRACTBackground: The problem of orphans is sensitive all over the world and causes challenge in caring and protection of their right and prosperity (UNICEF, 2017a). This study, intended to determine the effect of orphan institutionalization on child deprivation, child maltreatment and quality of life among the orphaned children in Zanzibar.Methods: Analytical cross-sectional study design was employed. Simple random sampling was used to select 374 participants from all five regions of Zanzi...

A case of a 22-month-old boy with necrotizing pneumonia presenting with leukaemoid reaction misdiagnosed as leukaemia: a case report and review of the literature

AbstractBackgroundNecrotizing pneumonia and hyperleukocytosis, to the extent of that seen in leukaemia, is a rarely reported presentation. The commonesttrigger of such a presentation is an inflammatory process caused by an overwhelming infection which leads to bone marrow irritation.However, the misdiagnosis of this clinical entity as leukaemia should be avoided at all costs so as to avoid the anxiety associated witha diagnosis of cancer, both to the patients and their families.Case presentat...

Clinical Predictors Of Malaria, Acute Bacterial Meningitis And Treatment Outcomes Among Febrile Children Admitted With Altered Mental Status In Northwestern Tanzania

ABSTRACT Background: Malaria and acute bacterial meningitis (ABM) are the leading infectious causes of febrile encephalopathy in malaria endemic settings. The clinical distinction of the two conditions is complicated by overlap in clinical features. Objective: To determine the clinical predictors for malaria, ABM and treatment outcome in febrile children aged 2 months to 12 years with altered mentation at two tertiary hospitals in Northwestern Tanzania. Methods: Prospective study of 10...

Estimation of the Risk of Cancer Associated with Pediatric Cranial Computed Tomography

Computed Tomography (CT) is a Iife saving tool for diagnosing Illness and injury in children (0 - 12 years). The use of computed tomography scan of the head, abdomenlpehris, chest or spine in children has increased were the last three decades [I]. Approximately 5 to 9 million CT examinations are performed annually on children in the United States 121. The increased use of CT in pediatrics, combined with variability in radiation doses, has resulted in many children receiving a high do...


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