Advancements in stem cell research have revolutionized regenerative medicine by offering innovative approaches for repairing damaged tissues and treating previously incurable diseases. This paper explores breakthroughs in induced pluripotent stem cells (iPSCs), CRISPR-based gene editing, and organoid development. Key potential therapies include regenerative treatments for neurological disorders, cardiovascular diseases, and diabetes. Despite the promise, ethical challenges, immune rejection, ...
Abstract: Ethiopia is claimed as the likely center of origin for okra [Abelmoschus esculentus (L).Moench], but few studies were conducted to assess the diversity of the crop in the country. Moreover, no attempt has been made to assess the diversity of okra genotypes for seed yield and related traits though the crop is known for the production of quality edible oil. Therefore, this study was conducted with the objectives of assessing genetic variability among okra genotypes for seed yield and...
Abstract: The ABO and Rh blood groups are the most important blood groups despite the long list of several other blood groups discovered so far. The ABO and Rh blood groups varies worldwide and are not found in equal numbers even among ethnic groups. Therefore, the objective of the study was to estimate phenotypic, genotypic and allelic frequencies of ABO and Rh blood groups among students of Oromo, Amhara and Gurage ethnic groups in Geresu Duki preparatory school in Woliso town, Oromia, Eth...
Abstract: The four blood types are known as A, B, AB, and O. Blood type A contains A antigen on the surface of red blood cells and B antibody on blood plasma. Type B blood contains the reverse combination. Serum of blood type AB contains neither antibody, but red cells in this type of blood contain both A and B substances. In type O blood, neither substance is present on the red cells, but the individual is capable of forming antibodies directed against red cells containing substance A nor B...
Abstract: The frequency of ABO and Rh-D blood group vary ethnically, geographically and from one population to another. Information on the distribution of ABO and Rh- D blood group is essential in relation to blood transfusion, clinical studies, genetic research and other health determination. There is no previous study reported the distribution of ABO and Rh- D blood groups in the population of Bordodde town. The aim of the present study was to determine Frequency of ABO and Rh (D) Blood Gr...
Abstract: The Knowledge of distribution of ABO and Rh blood groups is helpful for effective management of blood banks and safe blood transfusion services. The frequency of these blood groups varies worldwide and may not be found in equal numbers even among ethnic groups. The aim of this study was to find out the distribution of ABO and Rh (D) blood groups among students attending Chorora Secondary and Preparatory school in West Hararghe Zone Oromio Ethiopia. The study was designed from Janua...
Abstract: The purpose of this study was to identify grades 10 and 11 students’ misconceptions about cell biology and cell division, their sources and levels and to evaluate the effectiveness of biology teachers’ instructional methods to remediate students’ misconception. The study was carried out at KSPS, Somali Region, Ethiopia. The TTDT of cell biology and cell division was prepared and administered to 120 grade 10 and 11 students after their prior conceptions about the selected topi...
Abstract: The feeder free culturing of pluripotent stem cells aims to eliminate the use of mouse embryonic fibroblasts (MEFs) as substrate during in vitro culturing. Here, the potential of fibronectin and vitronectin to keep stem cells undifferentiated was compared using two different stem cell lines (HUES1 and HUES7). Cells were cultured on vitronectin and fibronectin for 3 weeks. Results showed that cells cultured in fibronectin appear to adhere slightly well initially while those in vitro...
Abstract: CrV1, a polydisperse DNA virus (polydnavirus or PDV) gene contributes to the suppression of host immunity in Cotesia genus parasitoids. Its molecular evolution was analyzed in relation to levels of resistance in the sympatric host species. Natural selection for nonsynonymous substitutions (positive Darwinian selection) was observed at specific amino acid sites among CrV1 variants; particularly, between parasitoid strains immune suppressive and nonimmune suppressive to the main resi...
Abstract: Yam (Dioscorea spp.) is an important food security crop with economic, nutritional, and medicinal value. It is a source of carbohydrates for millions of people in tropical and sub-tropical regions of Africa, Asia, South America, the Caribbean, and the South Pacific Islands. Determining the appropriate parents for breeding programs is the most important decision that plant breeders must make to maximize genetic variability and produce excellent recombinant varieties. However, adequa...
Abstract: Entomopathogenic fungi have been explored as a potential biopesticide to counteract the insecticide resistance issue in mosquitoes. However, little is known about the possibility that genetic resistance to fungal biopesticides could evolve in mosquito populations. Here, we detected an important genetic component underlying Anopheles coluzzii survival after exposure to the entomopathogenic fungus Metarhizium anisopliae. A familiality study detected variation for survival among wild ...
Abstract: Endophytic entomopathogenic species are known to systematically colonize host plants and form symbiotic associations that benefit the plants they live with. The actin-depolymerizing factors (ADFs) are a group of gene family that regulate growth, development, and defense-related functions in plants. Systematic studies of ADF family at the genome-wide level and their expression in response to endophytic colonization are essential to understand its functions but are currently lacking ...
Abstract: Plants are master regulators of rhizosphere ecology, secreting a complex mixture of compounds into the soil, collectively termed plant root exudate. Root exudate composition is highly dynamic and functional, mediating economically important interactions between plants and a wide range of soil organisms. Currently we know very little about the molecular basis of root exudate composition, which is a key hurdle to functional exploitation of root exudates for crop improvement. Root exp...
Abstract: We have chosen the urine innurioglobulin M (IgM) as system to study glycoprotein biosynthesis and carbohydrate processing. Secreted IgM heavy chain (m) has five glycoasylation sites which location and structures have been determined. chain variable region (VH) ia involved in antigen binding, while the constant region (CH) is responsible for the effect or functions in which the carbohydrate plays an important role.
Genetic diversity OF PLASMODIUM falciparum IN APPARENTLY HEALTHY SCHOOL children in ORE, Osun STATE.