Research Papers/Topics in Cell Biology and Genetics

Molecular Characterization Of Hepatitis B Virus In Rural And Semi-Urban Areas In The Central Region Of Ghana

ABSTRACT Hepatitis B virus (HBV) infection is a major cause of liver inflammation accounting for 887,000 deaths annually. The introduction of HBV vaccines has significantly reduced new cases of the infection, but there are still 65 million people living with the virus in Sub-Saharan Africa. Currently, 10 genotypes (A-J) of HBV have been classified. Several studies have shown that the different HBV genotypes differently influence clinical presentation, progression of liver diseases and respons...

Malaria-A climate Sensitive Disease

Abstract                  Every year thousands of people died due to malarial infection, mainly in developingcountries and under developed countries. In most of these places, the infected persons ‘age isbelow five and pregnant women are also affected by  malaria, this is due to weak and poorimmunity.  Another important reason is lack of awareness about malarial infection. In future, dueto climatic change, disease spreading population of mosquito will increase. It leads to a chanc...

TARGETING MACROPHAGES TO LIMIT MUSCLE DAMAGE

Table of ContentsAcknowledgements .................................................................................................................. IIAbstract ................................................................................................................................... III List of tables ........................................................................................................................... VIList of figures ...............................................

Chromosomal Study of two Cyprinid fishes of the genus Barbus; Barbus callipterus Boulenger 1907 and Barbus parablabes Daget 1957

The chromosomes of two cyprinid fishes of the genus Barbus; B. callipterus and B. parablabes were assessed in this study with a view to providing baseline information about the diploid chromosome number, karyotype and morphology. This study reveals that B. callipterus has a diploid chromosome number of 2n = 50, fundamental number of autosomal arms (NFa) of 66, and karyotype formula: 2n = 4m + 6sm + 6st +34T. On the other hand, B. parablabes has a diploid chromosome number of 2n = 50, fundamen...

Gene frequencies of ABO and Rh blood groups in Nigeria: A review

Background: ABO and Rhesus factor (Rh) blood type are germane in human life in genetics and clinicalstudies.Aim of the study: The review was undertaken with the objective to provide data on the ABO and Rh(D)blood group distribution and gene frequency across Nigeria which is vital for blood transfusion and susceptibility to disease.Materials and methods: Literature search for ABO/Rh blood distribution in Nigeria was done and allele frequencies of A, B, O, D and d were calculated from the frequ...

Nanotechnology and its applications in medicine

Chapter one : introductionApplication of nanotechnologyConclusion

A Review on the Medicinal Uses of Sunflower (Helianthus Annuus) Oil

ABSTRACT Sunflower   (Helianthus   annuus  L.)   is   a   genus   of   plants   comprising   about   70 species. It is famous for its unique nature of heliotropism and is the world’s most important source of oil. Around the world, sunflower production is 31.1m tons,with more than 26 ha under sunflower cultivation. Sunflower stalks have been used as fuel, fodder for livestock, food for poultry, and ensilage. Sunflower seeds were and still are eaten raw, roasted, cooked, ...

EVALUATION OF THE SUPPRESSIVE EFFECT OF THE ESSENTIAL OIL OF TITHONIA DIVERSIFOLIA ON PLASMODIUM BERGHEI IN LABORATORY MICE

ABSTRACT The evaluation of the anti malarial properties of the essential oil extract of Tithoniadiversifolia was carried out using the standard tests suppressive tests in laboratorymice.   The   Swiss   albino   mice   were   infected   with   rodent   malaria   parasite(Plasmodium berghei berghei) and were treated with 300mg/kg, 600mg/kg and1200mg/kg   dose   of the   oil   extracts.   The  result   showed   that   the  oil  extract  ofTithonia divers...

CLINICAL TRIAL REGULATION IN NIGERIA AND NAFDAC

This work describes the role of NAFDAC in the regulation of clinical trials in Nigeria. Clinical  trials  are  experiments  or  observation  done  in  clinical  research. Such prospective biomedical  or  behavioural  research  studies  on human participants are  designed  to  answer  specific  questions  about  biomedical  or behavioural  interventions,  including  new treatments (such  as novel vaccines, drugs, dietary choices, dietary supplements and medical device...

QUALITY ASSURANCE AND QUALITY CONTROL FOR WATER AND FOOD ANALYSIS

Great attention has been paid to food and water quality for centuries. The requirements have been changed according to the development of human knowledge in the field of nutrition, chemistry, microbiology, and analysis. It is necessary first to point out that the term food and water quality is a complex one that includes many indicators. For food and water to be classified as good, it has to fulfill the requirements, especially from the nutritional, sensory, hygienic-toxicological, and techn...

Antimicrobial Effect of Probiotic Lactobacilli on Candida Spp. Isolated from Oral Thrush of AIDS Defining Ill Patients

Abstract This study aimed at investigating the growth inhibitory effect of probiotic Lactobacillus on Candida species isolated from oral thrush of AIDS-defining ill patients. Clinical isolates of Candida species were obtained from Dalhatu Araf Specialist Hospital Lafia, Nasarawa State. de Man Rogosa Sharpe agar was used as starter culture for the isolation of Lactobacilli. The diameters of the antimicrobial assay were recorded using the following dilution in part per mL (1:10, 1:100, 1:1000,...

GENETICS OF EPILEPSY

Genetics is a huge and growing area across human biology, medicine and science, providing information about basic processes from birth to death, from development to degeneration, and in even revealing enough about disease biology to lead to new therapies or better use of existing treatments because gene activity underlines all biological process (Sisodiya, 1881; Vadlamudi et al., 2014).  Epilepsy is defined as one unprovoked (or reflex) seizure and a probability of further seizures similar t...


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