Research Papers/Topics in Laboratory Technology

Serum Cystatin C And Creatinine As Markers Of Kidney Function In Adults In Enugu State, Nigeria

ABSTRACTWith the increasing recognition of the several pitfalls of serum creatinine (SCr) andcreatinine-based glomerular filtration rate (GFR) estimates as measures of kidney function, anovel biomarker, cystatin C (Cys C) which is claimed to be superior to the creatinine-basedestimates has been proposed. However, this claim is yet to be validated in an indigenous blacksetting. This study was therefore, to verify this claim and to assess the best method to estimateGFR in a typical African...

Immunohistochemical Detection of Beta- Catenin in Ovarian Tumors Among Sudanese Women

This is hospital based analytical retrospective case control study was conducted at Soba university hospital, Omdurman military hospital, Omdurman maternity hospital (Khartoum state), and Sudan university of science and technology-college of medical laboratory science, during the period from September 2016 to February 2017. The study was aimed to detect beta-catenin expression in ovarian tumors, using immunohistochemistry. Forty paraffin block samples were collec...

Detection of Plasminogen Activator Inhibitor-1 Gene Mutation 4G/5G among Deep Venous Thrombosis Sudanese Adult Patients in Khartoum State

A number of prothrombotic and fibrinolytic disorders may lead to venous thromboembolism(VTE). Venous thrombo embolism(VTE) includes deep vein thrombosis (DVT)and pulmonary embolism(PE).The disease is caused by many factors some of which are congenital and others are acquired. A 4G/5G polymorphism located in the promoter region of plasminogen activator inhibitor-1 (PAI-1) gene has been found to be commonly associated with the high levels of PAI-1 and might be a ri...

Serum Magnesium Level And Related Biochemical Parameters in Cardiovascular Diseases at The Korle-Bu Teaching Hospital

ABSTRACT Background: Serum magnesium (Mg) and other biochemical abnormalities in cardiovascular diseases (CVD) is a global concern as it has been implicated in CVD related morbidity and mortality. However, results from studies of these biochemical abnormalities especially of serum magnesium in CVDs are conflicting and unclear with no data on CVD patients at the Korle-Bu Teaching Hospital; hence the focus of the current study. Aim: To determine serum magnesium and related biochemical par...

Serum Cytokine Profiles as Biomarker in Multi-Drug Resistant Tuberclosis

ABSTRACT Background: Tuberculosis (TB) remains a major threat to public health despite several efforts to curb the disease. Contributions made by TB control programs have been tremendous; however, the emergence of multi-drug resistant (MDR) tuberculosis is a big threat to the control efforts and calls for innovative measures to mitigate the effect. New TB control programs with a comprehensive approach to dealing with MDR-TB is needed globally. In particular, new nonsputum based diagnosti...

PREVALENCE OF PFHRP2 AND/OR PFHRP3 GENE DELETIONS IN PLASMODIUM FALCIPARUM ISOLATES AND THE PERFORMANCE OF HRP2 BASED MALARIA RAPID DIAGNOSTIC TESTS

ABSTRACTBACKGROUND: Malaria rapid diagnostic tests (MRDTs) are important for malariadisease management. However, performance of the RDTs is affected when the targetedantigens in the parasite have a variation or are altogether absent. The most commonparasite target antigen in RDTs, Plasmodium falciparum histidine-rich protein 2 (HRP2),has been reported to be absent in some P. falciparum parasites. Loss of the pfhrp2 in P.falciparum parasites affects the accuracy of PfHRP2 based RDT kits when t...

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CANCER OF THE LUNGS AND ITS PREVENTIONS

ABSTRACTCancer of the lungs has been one of the main causes of death recently, and still is, Lung cancer, also known as lung carcinoma, is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung. This growth can spread beyond the lung by the process of metastasis into nearby tissue or other parts of the body. Most cancers that start in the lung, known as primary lung cancers, are carcinomas. The two main types are small-cell lung carcinoma (SCLC) and non-sm...

Laboratory Analysis and Pipeline Products Marketing Company (PPMC) Depot Operations

ABSTRACTThis research work was carried out to evaluate the laboratory analysis of pipeline products marketing company (PPMC) depot operations. In the course of the research many scholarly articles on the subject matter were reviewed from which the researcher got lot information concerning the topic at hand. Thus making the research work a reliable source of information as far as facts about petroleum products marketing company (PPMC) is concerned.The Pipeline Inspectorate is charged with...

Products Contamination And Quality Control Analysis

SYNOPSIS Quality control can be seen as the activities that sustain the quality of a product in order to satisfy a given requirement or meet certain standards. (McGraw-Hill Dictionary, 2003). It is applicable in all phases of the production cycle. In food products, qualities such as composition, structure (molecular, microscopic and macroscopic), physicochemical and sensory attributes are all analyzed.  These analyse...

ANTIMICROBIAL ACTIVITIES OF LOCALLY PRODUCED SOAP AGAINST SOME PATHOGENIC ORGANISMS.

ABSTRACTThe evaluation of antimicrobial activities of five (5) brands of differentlocally producedsoap sold in Owo Local Government Area of Ondo state was carried out againstsome selected pathogenic organisms (Staphylococcusaureus,Enterobacteraerogenes,Bacillus cereus,Shigelladysentaries,Salmonella typhin,Candida albicans,Aspergillusfumigatus). Usually, the antimicrobial analysesof the soap samples were analysed. The analysis of antimicrobial activities of locallyproduced soaps against the pa...

EVALUATION OF MICROBIOLOGICAL QUALITY OF TANK WATER AT THE INSTITUTE OF MANAGEMENT AND TECHNOLOGY {IMT} CAMPUS III ENUGU

ABSTRACTThe evaluation of microbiological quality of tank water at the Institute of Management and Technology campus III Enugu was carried out by using ten samples of water obtained from ten different tank waters. For viable plate count for the presence of pathogenic organisms and organisms indicating organic matter pollution, plating technique of pour plates were used, also presence of coliform groups and Escherichia  coli were examined using the Presumptive, Confirmatory and Completed&...

COMPOSITION AND NUTRITIONAL PROPERTIES OF SEEDS FROM TROPICAL ALMOND (Terminalia catappa)

ABSTRACTTropical almond (Terminally catappa) fruit used in Eastern Nigeria have an impressive range of multipurpose medicinal uses with nutritional values. However, to be clinically used, more scientific data are needed. The goal of this study was to investigate the composition and nutritional properties of tropical almond. The seed of tropical almond was grind and analyzed for its proximate compositions and nutritional potentials and the results of this study showed that, the seed contained ...

Bioefficacy Study Of Mosquito Repellent Produced From Ocimum Basilicum Using Aerosol Propellant As Carrier

ABSTRACTMosquito borne disease is a major public health problem globally, particularly the tropics being the major spot in the spread of malaria. The development of resistance to chemical insecticides has necessitated the research and development of natural mosquito repellent. The aim of this study is to extract, characterize and test the larvicidal activity of essential oil, produce mosquito repellent using the essential oil as its active ingredient and study the bioefficacy of the produced ...


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