Prophylactic Efficacy of Aqueous Extract of Curcuma longa against Indomethacin-Induced Ulcer in Male Wistar Rats

Evaluation of the anti-ulcerogenic and
prophylactic efficacy of aqueous extract of
Curcuma longa on indomethacin-induced ulcer in
albino rats was the aim of this study. Thirty adult
male rats of body weight between 150 and 200g
were used and were divided into six groups of five
rats each. Group I was treated with 0.8mg/ml of
Omeprazole for seven days. Group II was treated
with a solution of 0.8 g/ml Curcuma longa for
seven days, while group III received distilled water
for seven days. This group served as the control
group. Groups IV, V and VI were treated similarly
as groups I, II and III respectively but were treated
for fourteen days. Gastric ulceration was induced
in the rats by the administration of 50 mg/kg
indomethacin after pre-treatment with distilled
water, omeprazole and Curcuma longa for 7 and
14 days respectively. Significant ulcer inhibition
was produced in the groups treated with Curcuma
longa and Omeprazole when compared with
control groups at p

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APA

Airaodion, A. (2019). Prophylactic Efficacy of Aqueous Extract of Curcuma longa against Indomethacin-Induced Ulcer in Male Wistar Rats. Afribary. Retrieved from https://afribary.com/works/prophylactic-efficacy-of-aqueous-extract-of-curcuma-longa-against-indomethacin-induced-ulcer-in-male-wistar-rats

MLA 8th

Airaodion, Augustine "Prophylactic Efficacy of Aqueous Extract of Curcuma longa against Indomethacin-Induced Ulcer in Male Wistar Rats" Afribary. Afribary, 29 Mar. 2019, https://afribary.com/works/prophylactic-efficacy-of-aqueous-extract-of-curcuma-longa-against-indomethacin-induced-ulcer-in-male-wistar-rats. Accessed 20 Apr. 2024.

MLA7

Airaodion, Augustine . "Prophylactic Efficacy of Aqueous Extract of Curcuma longa against Indomethacin-Induced Ulcer in Male Wistar Rats". Afribary, Afribary, 29 Mar. 2019. Web. 20 Apr. 2024. < https://afribary.com/works/prophylactic-efficacy-of-aqueous-extract-of-curcuma-longa-against-indomethacin-induced-ulcer-in-male-wistar-rats >.

Chicago

Airaodion, Augustine . "Prophylactic Efficacy of Aqueous Extract of Curcuma longa against Indomethacin-Induced Ulcer in Male Wistar Rats" Afribary (2019). Accessed April 20, 2024. https://afribary.com/works/prophylactic-efficacy-of-aqueous-extract-of-curcuma-longa-against-indomethacin-induced-ulcer-in-male-wistar-rats

Document Details
Field: Biochemistry Type: Article/Essay 5 PAGES (2602 WORDS) (pdf)