ABSTRACT
The synthesis and characterization, spectroscopic, and biological studies of 2-acetylferrocenyl-4- phenylthiosemicarbazone, 2-acetylferrocenyl-4-methylthiosemicarbazone, 2-acetylpyridine-2- thiophenecarboxylsemicarbazone and 2-acetylferrocenyl-2-thiophenecarboxylsemicarbazone with copper(II) chloride are reported here. The ligands were synthesized by condensation reaction of appropriate carbonyl and amine compounds. The reactions were carried out in the presence of acetic acid. The complexes were characterized by means of Elemental Analysis (EA), Fourier Transform Infrared (FT-IR) spectroscopy, Nuclear Magnetic Resonance ( 1HNMR and 13CNMR) spectroscopy. The metal complexes and their corresponding ligands were tested against malaria parasites. It was found that the copper complexes synthesized are more biologically active then their corresponding ligands.
LIKIUS, D (2021). The Synthesis And Characterization Of Copper(Ii) Complexes Containing Thiosemicarbazone And Semicarbazone Ligands Derived From Ferrocene And Pyridyl Fragments. Afribary. Retrieved from https://afribary.com/works/the-synthesis-and-characterization-of-copper-ii-complexes-containing-thiosemicarbazone-and-semicarbazone-ligands-derived-from-ferrocene-and-pyridyl-fragments
LIKIUS, DANIEL "The Synthesis And Characterization Of Copper(Ii) Complexes Containing Thiosemicarbazone And Semicarbazone Ligands Derived From Ferrocene And Pyridyl Fragments" Afribary. Afribary, 19 Apr. 2021, https://afribary.com/works/the-synthesis-and-characterization-of-copper-ii-complexes-containing-thiosemicarbazone-and-semicarbazone-ligands-derived-from-ferrocene-and-pyridyl-fragments. Accessed 16 May. 2024.
LIKIUS, DANIEL . "The Synthesis And Characterization Of Copper(Ii) Complexes Containing Thiosemicarbazone And Semicarbazone Ligands Derived From Ferrocene And Pyridyl Fragments". Afribary, Afribary, 19 Apr. 2021. Web. 16 May. 2024. < https://afribary.com/works/the-synthesis-and-characterization-of-copper-ii-complexes-containing-thiosemicarbazone-and-semicarbazone-ligands-derived-from-ferrocene-and-pyridyl-fragments >.
LIKIUS, DANIEL . "The Synthesis And Characterization Of Copper(Ii) Complexes Containing Thiosemicarbazone And Semicarbazone Ligands Derived From Ferrocene And Pyridyl Fragments" Afribary (2021). Accessed May 16, 2024. https://afribary.com/works/the-synthesis-and-characterization-of-copper-ii-complexes-containing-thiosemicarbazone-and-semicarbazone-ligands-derived-from-ferrocene-and-pyridyl-fragments