ABSTRACT An investigation of the Impact of Gender Equality on Involvement of Women in Administration was conducted in Juba County and Terreka County, Southern Sudan. The variable considered includes; forms of gender equality in society, its effects in the society and the attempts to curb it. The general survey research design was used, methods used in data collection include; oral interviews, questionnaires, observation in the societies. The study revealed that the major forms Gender Equalit...
ABSTRACT Sub-Saharan Africa accounts for high tuberculosis cases that result from widespread HIV infections, which is exacerbated by injection substance use. Immunologically, HIV critically impairs cell-mediated host responses to Mycobacterium tuberculosis. IFN-γ, IL-10 and Acrp30 are key mediators of systemic inflammation. Although circulating IFN- and IL-10 levels are increased, Acrp30 levels are lowered and associated with disease severity among HIV and TB co-infected non-susbstance u...
ABSTRACT Tuberculosis (TB) causes substantial human morbidity and mortality globally. About 10.4 million TB cases and 1.4 million deaths worldwide were reported in 2015. Kenya is among the 22 countries with highest TB burden. Microscopy is routinely used for Mycobacterium tuberculosis bacilli (Mtb) detection; however its sensitivity has been reported to be as low as 60% posing a problem for case detection. Rifampicin (RIF) is one of the major drugs for first line TB treatment; however, most p...
ABSTRACT Among human parasitic diseases, malaria is the most important and it has global incidence of 300 to 500 million cases per year with about 1.5 million deaths among African children. Recently the disease has been subjected to massive control efforts with varying degrees of success. The development of parasite and vector resistance to conventional drugs and insecticides has complicated both treatment and control today. The main goal of this project was to identify viable phytomedicines ...
TABLE OF CONTENTSDECLARATION ............................................................................................................ iAPPROVAL .................................................................................................................. iiDEDICATION ............................................................................................................ iiiACKNOWLEDGEMENT ................................................................................................
TABLE OF CONTENTSDECLARATION ............................................................................................................................. iAPPROVAL ................................................................................................................................... iiTABLE OF CONTENTS .............................................................................................................. iiiLIST OF TABLES ......................................................
ABSTRACT The present study investigates the possibility of enhancing the solubility, and hence the bioavailability of poorly water soluble glimepiride via formation of polyethylene glycolpolyvinyl caprolactam - polyvinyl acetate grafted copolymer (Soluplus®) and PEG 4000 based solid dispersions by solvent evaporation technique.Different batches of glimepiride solid dispersions (SD) were prepared using solvent evaporation method with Soluplus® and PEG 4000 as polymer matrix at different rat...
ABSTRACT The present study investigates the possibility of enhancing the solubility, and hence the bioavailability of poorly water soluble glimepiride via formation of polyethylene glycolpolyvinyl caprolactam - polyvinyl acetate grafted copolymer (Soluplus®) and PEG 4000 based solid dispersions by solvent evaporation technique.Different batches of glimepiride solid dispersions (SD) were prepared using solvent evaporation method with Soluplus® and PEG 4000 as polymer matrix at different rati...
ABSTRACT Background: Tuberculosis (TB) remains a major threat to public health despite several efforts to curb the disease. Contributions made by TB control programs have been tremendous; however, the emergence of multi-drug resistant (MDR) tuberculosis is a big threat to the control efforts and calls for innovative measures to mitigate the effect. New TB control programs with a comprehensive approach to dealing with MDR-TB is needed globally. In particular, new nonsputum based diagnostic to...
TABLE OF CONTENTSDECLARATION ................................................................................................................................... iAPPROVAL. ....................................................................................................................................... iiDEDICATION .................................................................................................................................... iiiACKNOLEDGEMENT ............................
ABSTRACT The prevailing tuberculosis (TB) situation in the world demands the re-engineering and repositioning of some old drug families to achieve effective control of the spread and effects of TB. One such drug that is targeted for re-engineering is isoniazid which is also known as isonicotinohydrazide (INH). In this study, theoretical studies have been carried out to investigate twenty eight structural analogues of the isoniazid (INH) for their reactivity and some drug-likeness. The density...
Abstract Background: Acetylated starches with degrees of substitution (DS) of > 2 have been found suitable for sustained release applications because of their hydrophobic nature and thermoplasticity. The short half-life and high dosing frequency of repaglinide make it an ideal candidate for sustained release. Objectives: To formulate and evaluate repaglinide microspheres using acetylated starch of the indigenous rice species Oryza glaberrima Steud (Ofada) as polymer. Materials and Methods: Of...
The current problems facing the Kenyan pupil require Guidance and Counseling (G&C) teachers to be knowledgeable about psychological and behavioral interventions, both at the preventive and responsive levels. Despite the fact that Kikuyu Sub County public primary schools record high incidences of pupils’ absenteeism, alcohol and drugs abuse, psychosocial and teenage sexuality issues, G&C activities are very minimal. The main purpose of this study was to assess the G&C programmes’ capa...
ABSTRACT The study was designed to determine prevalence and patterns of Psychoactive Substance use among Senior Secondary School Students in Dala Local Government Area (LGA), Kano State Nigeria. The study adopted a cross sectional descriptive survey design. Simple random sampling procedure was used to select two Secondary Schools out of the ten Government Senior Secondary School in Dala LGA, of Kano State. Both Schools have a combined population of 2293 students made up 1202 boys and 1096 gi...
ABSTRACT This study concerns the problem facing free primary education such as inadequate teaching persmmel, teacher distribution, gender disparities, poverty, political interference, immorality, bad peer groups, drug abuse among others. It is also an investigation of how effective this problem can be solved .The researcher gives various methods in collecting data including questionnaire, interview, and observation ,he particularly commonly used a questionnaire because it is more advantageous...