ABSTRACT Reproductive tract infections (RTIs) are a major public health problem especially in the developing world. As part of measures to control the spread of these infections, the World Health Organization recommended syndromic management. This study set out to determine the prevalence patterns, molecular characteristics and antibiotic susceptibility of reproductive tract pathogens isolated from women of child bearing age with the aim of contributing useful information to policy formulati...
ABSTRACT Terminalia superba Engl. & Diels (Combretaceae), is a member of the genus Terminalia that comprises around 100 species distributed in tropical regions of the world. In Africa it is found along the coast of west and central Africa. It has different uses in traditional medicine such as antimalarial, anti-diabetic, anti-fungal, and anti-hypertensive in the areas where it is found. Most of these uses are yet to be scientifically investigated. The powdered stem bark of Terminalia superba...
ABSTRACT S t a r c h e s have t r a d i t i o n a l l y been used i n t h e pharmaceutical i n d u s t r y as f i l l e r , binder and d i s i n t e g r a n t . Pharmaceutical grade s t a r c h e s a r e derived mainly f r o m maize g r a i n s and potato tubers. C u r r e n t advances i n t a b l e t t i n g technology, e s p e c i a l l y the use of high-speed, mu1 ti-station r o t a r y t a b l e t presses, and d i r e c t compression t a b l e t t i n g t e c h n i q u e s , have n e c e ...
ABSTRACT S t a r c h e s have t r a d i t i o n a l l y been used i n t h e pharmaceutical i n d u s t r y as f i l l e r , binder and d i s i n t e g r a n t . Pharmaceutical grade s t a r c h e s a r e derived mainly f r o m maize g r a i n s and potato tubers. C u r r e n t advances i n t a b l e t t i n g technology, e s p e c i a l l y the use of high-speed, mu1 ti-station r o t a r y t a b l e t presses, and d i r e c t compression t a b l e t t i n g t e c h n i q u e s , have n e c e ...
ABSTRACT In the tropics, malaria has become the most alarming public health problem, hence the need for a mosquito repellent, a personal protection against the vector. The concern about the deleterious effects associated with synthetic chemicals like N, N-diethy-3-methylbenzamide (DEET) has elicited the interest to explore plant materials as source of natural repellent for mosquito control. The aim of this study was to formulate and evaluate herbal mosquito repellent cream based on solid lip...
ABSTRACT There is a growing industrial demand for peptones of non-animal origin owing to legislations as well as outbreak of animal-associated diseases. Microbiological growth media developed from legumes as sources of protein hydrolysates are limited. It is, therefore, the aim of this study, to produce comparatively standard protein hydrolysates from Prosopis africanaseed that can be used as peptone for microbial culture in place of animal peptone. Prosopis africana seeds (2.5kg) were purch...
Abstract The study was carried out to determine pharmacognostic standards, phytochemical constituents, evaluate the antioxidant and hepatoprotective activities of the extract and fractions of Annona senegalensis Pers. (Annonaceae) by employing both the in vitro and in vivo experimental models. The acute toxicity tests result showed the drug is safe at 5000mg/kg doses. The effect of DPPH free radical scavenging, ABTS radical scavenging, Hydroxyl radical scavenging, Hydrogen peroxide scavengi...
ABSTRACT The antimicrobial activities of two Nigerian medicinal plant commonly used as chewing sticks Zanthoxylum xanthoxyloides and Pseudocedrela kotschyi antimicrobial activities were investigated against 7clinical strains of Streptococcus mutans, Staphylococcus aureus ATCC 29213, Candida albicans, Candida tropicalis and Candida krusei ATCC 6825. The antibacterial and antifungal activities of the extracts were determined using the agar well diffusion and surface plate method respective...
ABSTRACT The processing technique for production of alpha and microcystalline cellulose using Sorghum bicolor and Andropogon gayanus as starting materials was established. The effect of reagent type and concentration, pH, temperature, digestion and bleaching time on the quality and yield of the powdered cellulose grades &as studied. Acute toxicity test on the derived polymers was investigated using albino mice. The physicotechnical properties of the new polymeric materials were studied. A Car...
ABSTRACT: Tuberculosis is a global burden with one –third of the world’s population infected with the pathogen Mycobacterium tuberculosis and an annual 2 million deaths from the disease. This high incidence of infection and the increased rate of resistant strains of the organism (MDR- and XDR- TB) have called for an urgent need to develop new anti-tuberculosis drugs from plants. The crude extract of Uvaria afzelli Scott Elliot (Annonaceae) root bark, and leaves and root bark of Tetracera ...
ABSTRACT ;/ descript ive cross -, section analysis 0/ five hundred patients who were symptomatically diagnosed of malaria in three locations: Saki (peri-urban), Ibadan (urban) and Lagos (highly urbanized) were recruited /01' this study using a well structured questionnaire between September 2005 and June 2006. The prevalence 0/ both malaria and HIV infections were higher in Peri-Urban town than the other two locations. We observed that 80% were HIV positive in Saki. 20% in Ibadan and 37. J % ...
ABSTRACT The aqueous methanolic extracts of 20 selected plant parts were screened for in-vitro antimicrobial activity against clinical strains of Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumonia, Salmonella typhi, Escherichia coli, Pseudomonas aeruginosa, Aspergillus niger and Candida albicans at a test concentration of 10mg/ml using the agar well diffusion method and penicillin G, chloramphenicol and Nystatin as controls. The seeds of Parkia biglobosa, Glycine max, Voendzeia s...
ABSTRACT Hawked foods are cheap and easily accessible and have met the food needs of people in many cities and towns of developing countries. This study was aimed at ascertaining the diversity of microbial contaminants in foods hawked in Nsukka town. Seven different food samples of cooked foods hawked in Nsukka were examined for the presence of bacterial and fungal contaminants using the streak plate method on sterile nutrient agar plates and SDA plates respectively. The foods included; pige...
ABSTRACT There has been an increase in the occurrence of antibiotic resistance among Salmonella enterica, one of the commonest causative agents of Salmonella infections. Fluoroquinolones and third generation cephalosporins are usually the drugs of choice in the management of Salmonella infections. Previous reports have indicated common occurrence of multi-drug resistance (MDR) including resistance to β-lactams and fluoroquinolones among clinical Gram-negative organisms. However, there is pa...