MCB 415: THEORIES OF ENZYME CATALYSIS

HOW ENZYMES WORK

SOURCE OF BINDING ENERGY

THEORIES OF ENZYME CATALYSIS

APPROXIMATION/PROXIMITY EFFECT

ACID- BASE CATALYSIS

CATALYTIC TRIAD/CHARGE RELAY NETWORK

COVALENT CATALYSIS

Role of metal ions in catalysis

Metal ions in catalysis

Electrostatic catalysis

Catalysis by Orientation

Catalysis by Strain or Bond Distortion