MI Paste PLUS effect to prevent white spot lesions associated with orthodontic treatment [October 25, 2016]

Search result: Three contradicting clinical trials were found so far.

Clinical outcomes: Some results show that MI Paste Plus appears more effective in reducing white spot lesions than placebo and fluoride varnish after 3 months, while other results suggest that its effect appears to be equal to that of normal home care after 2 months. The quality of the existing evidence requires further assessment.

[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]