ANTI-TRYPANOSOMAL ACTIVITY OF N-HEXANE AND DICHLOROMETHANE EXTRACTS OF VITELLARIA PARADOXA LEAVES ON TRYPANOSOMA BRUCEI BRUCEI INFECTED MICE

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African trypanosomosis is a vector-borne disease that is caused by a flagellated protozoon of the genus Trypanosoma. Large populations of human and domestic animals are at risk of infections with trypanosomes in vast areas of sub-Saharan Africa where the disease is endemic. Human infections with trypanosomes are referred to as Human African Trypanosomosis (HAT) while animal infections are known as African Animal Trypanosomosis (AAT). These infections are more prevalent in the rural areas (Atouguia and Costa,1999 Hoet et al, 2007) and are transmitted through the bite of infected tsetse flies (Glossina spp). Trypanosomosis is of great significance to human health and animal production in Africa (Bizimana et al., 2006).

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