In this study, zinc oxide nanoparticles (ZnO NPs) were synthesized using an aqueous extract of the Ocimum lamifolium (O.lamifolium) plant. The I optimal coordinate exchange random response surface methodology (RSM) was used to optimize the effect of the zinc acetate precursor, temperature, and time on ZnO NPs by designing nine runs. From ANOVA analysis, the significance and validity of the designed models showed that the optimal values of the zinc acetate precursor, temperature, and time during ZnO NPs synthesis were found to be∼0.06 M,∼30 °C, and ∼1.35 h, respectively. The obtained ZnO NPs under these optimized conditions were characterized and explored by UV−vis, TGA/DTA, FTIR, XRD, SEM-EDX, TEM, HRTEM, and SAED. Furthermore, the electrocatalytic performance of ZnO NPs was performed for sulfamethoxazole (SMZ) sensing activity with a 0.3528 μM (S/N=3) limit of detection (LOD). In addition, an antibacterial study revealed that ZnO NPs confirmed excellent zone of inhibition against E.coli, S.aureus, P.aeruginosa, and S.pyogen pathogenic resistance bacterial strains at concentrations of 50,75,and100 μg/mL. Thus, ZnO NPs synthesized using the O.lamifolium leaf have a potential electrocatalytic activity for diverse organic pollutant detection as well as a desirable material for such drug resistance antimicrobial strains.
Dessie, Y. (2023). Biosynthesis and Optimization of ZnO Nanoparticles Using Ocimum lamifolium Leaf Extract for Electrochemical Sensor and Antibacterial Activity. Afribary. Retrieved from https://afribary.com/works/biosynthesis-and-optimization-of-zno-nanoparticles-using-ocimum-lamifolium-leaf-extract-for-electrochemical-sensor-and-antibacterial-activity
Dessie, Yilkal "Biosynthesis and Optimization of ZnO Nanoparticles Using Ocimum lamifolium Leaf Extract for Electrochemical Sensor and Antibacterial Activity" Afribary. Afribary, 21 Aug. 2023, https://afribary.com/works/biosynthesis-and-optimization-of-zno-nanoparticles-using-ocimum-lamifolium-leaf-extract-for-electrochemical-sensor-and-antibacterial-activity. Accessed 15 May. 2024.
Dessie, Yilkal . "Biosynthesis and Optimization of ZnO Nanoparticles Using Ocimum lamifolium Leaf Extract for Electrochemical Sensor and Antibacterial Activity". Afribary, Afribary, 21 Aug. 2023. Web. 15 May. 2024. < https://afribary.com/works/biosynthesis-and-optimization-of-zno-nanoparticles-using-ocimum-lamifolium-leaf-extract-for-electrochemical-sensor-and-antibacterial-activity >.
Dessie, Yilkal . "Biosynthesis and Optimization of ZnO Nanoparticles Using Ocimum lamifolium Leaf Extract for Electrochemical Sensor and Antibacterial Activity" Afribary (2023). Accessed May 15, 2024. https://afribary.com/works/biosynthesis-and-optimization-of-zno-nanoparticles-using-ocimum-lamifolium-leaf-extract-for-electrochemical-sensor-and-antibacterial-activity