Chemical Characterization and Biological Activity of Flavonoids in Some Medicinal Plants

Subscribe to access this work and thousands more

In this study Three plants species from eastern and western Sudan were studied: Namely Acacia nubica benth( Laot), Citrus paradise (grapefruit ) and Combretum Hartmonnina Schweinf (Habeel )The plant material was extracted using 95% ethanol.The crude extracts were subjected to a phytochemical screening which revealed the presence of flavonoids among other phytochemicals .The crude extracts were purified by thin layer chromatography utilizing different solvent systems ,and characterized using : IR,UV, HNMR and Mass spectroscopy . Aflalavonoid :7,5 ´ ,6 ´ - trihydroxy-5-methyl-isoflavone was isolated from the bark of Combretum Hartmonnina Schweinf (Habeel )5,7,4 ´ ,5 ´ -tetrahydroxy-6,8,1´ ,2 ´ ,6 ´ -pentamethoxyflavanone was isolated from the leaves of Acacia nubica and7-oglycosyl-5,4 ´ dihydroxyflavanone was isolated from the leaves of Citrus paradiseThe isolated flavonoids revealed promising antimicrobial potential.

Subscribe to access this work and thousands more