PREVALENCE OF HELICOBACTER PYLORI IGG AND STOOL ANTIGEN DETECTION FROM DYSPEPTIC
PATIENTS IN JOS, NIGERIA
Ombugadu, D.O1
, Oladele O.V1,2, Onuoha, S. C3* Omisope , O4
and Ani, A1
1Department of Medical Microbiology, Faculty of Medical Sciences, University of Jos, P.M.B 2084 Jos , Plateau State, Nigeria;
2Department of Educational Services, Universal Basic Education, P.M.B 163 Garki Abuja, Nigeria. 3Department of
Biotechnology, Ebonyi State University, Abakaliki, Ebonyi State, Nigeria. 4Department of Chemical Pathology, Obafemi
Awolowo University Teaching Hospital Complex, Ile-Ife, Osun State
*Correspondence: sconuoha@yahoo.com; Tel: +2348032385682
ABSTRACT
Helicobacter pylori is a helical shaped gram negative microaerophilic bacterium, that can inhabit various areas of the stomach.
The study was carried out to determine the prevalence of Helicobacter pylori infection among dyspeptic patients attending
Endoscopy unit, Jos University Teaching Hospital (JUTH). The prevalence of H pylori; antibodies in plasma and antigen in stool
samples of 80 patients examined was studied using ELISA (DIA PRO, Italy) and ICA (BIOTEST China) respectively. Sociodemographic and clinical information was obtained through the assistance of attending gastroenterology staff. Blood grouping
was also performed by slide agglutination test for all patients. Helicobacter pylori IgG antibodies were detected in plasma of 28
(35%) patients of which 27 patients out of the sero-positive cases were antigen positive while Helicobacter pylori antigen was
detected in the stool of 31 (38.8%) patients of which 27 patients out of the antigen positive cases were also seropositve. No
significant association was found between Helicobacter pylori and age, sex, ABO blood group, economic status, source of water
and consumption of alcohol. Thus, Helicobacter pylori seropositivity with respect to blood groups was found to be 32.6%, 46.7%,
33.3% and 33.3% in blood groups O, B, A and AB respectively, while Helicobacter pylori stool antigen test positive results was
found to be 33.3%, 33.3%, 46% and 39.5% in blood groups O, B, A and AB respectively. Hence, no statistical association was
found between Helicobacter pylori infection and blood groups of the patients (P>0.05). However, marital status was
significantly associated with Helicobacter pylori antibody test (P
Ombugadu, D. (2019). PREVALENCE OF HELICOBACTER PYLORI IGG AND STOOL ANTIGEN DETECTION FROM DYSPEPTIC PATIENTS IN JOS, NIGERIA. Afribary. Retrieved from https://afribary.com/works/david-ovey-ombugadu-publiction
Ombugadu, David "PREVALENCE OF HELICOBACTER PYLORI IGG AND STOOL ANTIGEN DETECTION FROM DYSPEPTIC PATIENTS IN JOS, NIGERIA" Afribary. Afribary, 07 Feb. 2019, https://afribary.com/works/david-ovey-ombugadu-publiction. Accessed 05 Nov. 2024.
Ombugadu, David . "PREVALENCE OF HELICOBACTER PYLORI IGG AND STOOL ANTIGEN DETECTION FROM DYSPEPTIC PATIENTS IN JOS, NIGERIA". Afribary, Afribary, 07 Feb. 2019. Web. 05 Nov. 2024. < https://afribary.com/works/david-ovey-ombugadu-publiction >.
Ombugadu, David . "PREVALENCE OF HELICOBACTER PYLORI IGG AND STOOL ANTIGEN DETECTION FROM DYSPEPTIC PATIENTS IN JOS, NIGERIA" Afribary (2019). Accessed November 05, 2024. https://afribary.com/works/david-ovey-ombugadu-publiction