Research Papers/Topics in Pharmacy

Assessment Of The Quality And Dissolution Profiles Of Branded Fixed Dose Artemetherilumefantrine Tablets Sold At Pharmacies In Kampala- Uganda

ABSTRACTThis study was done to evaluate the physicochemical properties, quality control parameters andthe dissolution profiles of circulating samples of artemether/lumefantrine sold at Pharmacies inKampala. The physicochemical parameters and assay of thirteen ( 13) brands of the productswere assessed through the evaluation of uniformity of tablet weight, friability test, disintegrationtest and assay of active pharmaceutical ingredients according to established methods.The dissolution rat...

Acute Toxicity And Histological Sudy Of Nalongo's Renal/Hepatic Disorder Potion In Rats

ABSTRACTThe history of use of herbal medicine dates back to more than 4000 years. A wide range of plantshave been utilized for treatment of multiple disorders of the liver. The utilization has been asextracts of single plants and also compound preparations of more than one-plant type. Herbalmedicine has been categorically employed for a variety of medical problems and modern trendshave helped in extracting the active ingredients which have been classed into many chemicalgroups such as al...

Trend Analysis And Therapeutic Management Of Mental Disorders In Central And Eastern Uganda Between 1970-2005

ABSTRACTThe consequence of political and bloody civil strives in Uganda exposed people to health damaging psychological.physical. chemical. biological and mechanical stressors. with estimated 35% Ugandan sufferingfrom some form or mental disorders. There is dearth of in formation on the impact on the trend evolution andpattern or mental disorders in the two regi ons.This study aims to determine the epidemiology of mental disorders and their patterns of presentation inEastern and Centra...

Role Of Macronutrients In The Modulation Of The Gut Microbiota Of Drosopila Melanogaster

ABSTRACTThe study on the role of macronutrients on modulation of gut microbiota of Drosophila me/anogaster was carried out in institute of biomedical research laboratory of Kampala international university western campus.The study found that diet and age have influence on gut microbiota. From the findings, the population is recommended to eat well balanced diet.

Use Of Mobile Phones For Monitoring Adverse Drug Reactions In "Open System Pharmacy" In Ishaka, Bushenyi District

ABSTRACTAdverse drug reactions (ADRs) are significant causes of morbidity and mortality and may causemany hospitalizations leading to large economic burdens to patients and to society. Postmarketingsurveillance offers assessment of drug released to the market in different categories ofpeople, other than those in whom the drug was tested. However dmg reactions are currently littleor not monitored from the open system pharmacy comprising of community pharmacies anddrug stores. This study e...

Evaluation Of The Effects Of Lumefantrine Component Of Coartem On Electrical Conductivity Of The Heart In Patients Taking Coartem In Management Of Uncomplicated Malaria In Klu-Th Bushenyi Dis

ABSTRACTBackground: Approximately 2.37 billion people Jive in areas at risk for transmission Of pfalciparummalaria, mainly in sub-Saharan Africa (Hay, et al., 2009).Combination Artemether/Lumefantrine (Coartem, Riamet, and Falcynate-LF) is a fixed dose Artemisininbasedcombination therapy (ACT) indicated for the treatment of acute uncomplicated PlasmodiumJalciparum malaria. It is an effective and well tolerated treatment providing high cure rates even in areaswith multi-drug resistance. Ca...

Physico-Chemical Studies Of The Lower River Niger,

AB ST R ACTPhysico-chcmical analyses of t h e surface waters of the lower reaches of the River Niger were carried out for a per iod of one year ( ~ p r i l1 988 - March 1989) covering both t h e rainy and dry seasons t o e ; t a b l i s h Levels of various pollutants and t o study t h t , contribut ions made by the major t r i b u t a r i e s ~ n udrb an a c t i v i t i e s to the gross pollution level. Cerzain physico-chemical properties such as BOD, COD, o...

In Vitro Equivalence Studies And Comparative Assessment Of Generic Metronidazole Tablets Commercially Available Under Biowaiver Conditions In Nigeria.

ABSTRACTThe aim of the present study was to investigate the physicochemical equivalence and comparethe dissolution rate of thirteen brands of metronidazole tablets collected from retailpharmacies in Nigerian markets.This study sought to apply the BCS biowaiver requirements to assess the equivalence ofcommonly interchanged generic Metronidazole tablets with their innovator product inNigeria.Solubility of active pharmaceutical ingredients (API) has always been a concern forformulators, sin...

Study On The Formulation Of Pantoprazole Microspheres And Tablets Using Mucuna Pruriens Starch

INTRODUCTION In pharmaceutical sciences, microspheres have been extensively studied for use as drug delivery systems, where they have been shown to protect sensitive drugs from enzymatic degradation and allow controlled release, and tissue targeting of the formulated drug. Starch modification, can be used to tailor starch to specific applications. Pantoprazole, a proton pump inhibitor which suppresses the acid production by inhibiting the H+ K+ATPase. In this study, M. pruriens starch, ...

Pharmacognostic And Lactogenic Studies Of The Leaves Of Stachytarpheta Jamaicensis (L.) Vahl (Verbenaceae)

ABSTRACTBased on the ethnomedicinal use and belief that Stachytarpheta jamaicensis (SJ)can increase milk supply in lactating women, experimental studies were carried outto determine the effect of crude methanol extract (CME) and fractions of SJ leaveson serum PRL levels. The pharmacognostic standards, preliminary phytochemicalanalysis and acute toxicity study were also carried out. The fresh leaves werecollected, cleaned, air-dried and pulverized. A photomicroscope was used in thequalitative ...