ABSTRACT New series of four, (Z)-5-(4-chlorobenzylidine)-2-(Aryl/Substituted arylimino) thiazolidin-4-one and one (Z)-5-(4-chlorobenzylidine)-3-(2,5- dichlorophenyl)-2-iminothiazolidin-4-one were successfully synthesized from aryl/substituted aryl amines by employing nucleophilic substitution reaction with chloroacetyl chloride to form chloroacetamide. The formed acetamides were nucleophilically reacted with potassium thiocyanate coupled with Cyclization to form N-substituted thiazolidin-4-o...
ABSTRACT A large number of hetero-aromatic and carbonyl molecules are useful in pharmaceutical and dye industries. Studies of their transition dipole moment (Δμ) and transition polarizability (Δα) are important because they determine their solubility and usefulness. Experimental determination of these parameters and other electronic properties such as oscillator strength (f) using Solvatochromic Shift Equations (SSE) has proved to be unreliable. This is due to the large spread in their re...
ABSTRACT Metal complexes have interesting properties and varied applications in light emitting diodes. A number of substituted pyridine metal (Rhenium, Ruthenium and Iridium) complexes have been synthesised and characterised. However, the synthesis and characterisation of substituted pyridine iron complexes such as Tricarbonyl (1-4-η- pyridino-cyclohexa-1,3-diene) iron complexes for its light emitting property remain scanty. Therefore, this research was designed to synthesise, characterise a...
ABSTRACT Untreated industrial effluents discharged into land and surface water are of great environmental concern. Previous studies on physicochemical characteristics of effluents and sediments from discharged points of various industrial sectors in Lagos metropolis are inadequate in scope, duration, chemical treatment options and estimated pollutant discharge load which are of importance in waste water management. This study was designed to investigate the physicochemical characteristics of ...
ABSTRACT Depression has been the number one disease, causing a high motility rate in the world, marking the need for new highly effective antidepressants that can alleviate the situation. Unfortunately, the price of carrying out experimentally the whole process of drug discovery and design costs an endeavor billion of money. Yet, computer-aided drug design is a cost-effective way of obtaining new potential drugs within a short period of time. A study helpful in designing potent drug candidat...
ABSTRACT Kinetic and mechanistic investigations on the reactions of ozone with phenol and some of its derivatives (hydroquinone, catechol, phloroglucinol, pentachlorophenol, pentabromophenol, 1,2- dimethoxybenzene, 1,4-dimethoxybenzene and 1,3,5-trimethoxybenzene) have been carried out. These compounds were chosen, as they can serve as models for compounds which are abundant in surface waters and wastewater. The scope of the investigation was widened by including dihydrogen sulfide, often a ...
ABSTRACT Environmental pollution caused by persistent and bioaccumulative toxic chemicals is a global issue in view of its effects on biota. Researches abound on the sources and concentration of soil pollutants but there is paucity of information on their sorption/desorption in Nigerian soils. This is necessary for accurate prediction of toxicity and effective remediation strategy. Therefore, this study was aimed at assessing the sorption/desorption of selected organic and inorganic pollutant...
ABSTRACT Eighty-eight divalent metal complexes derived from dihydrazides of oxalic, malonic, succinic, adipic, phthalic and :erephthalic acids, with manganese( 11), cobalt(ll), nickel(ll), copper(IJ), zinc(ll), cadmium(ll), mercury(ll) and magnesium tetrafluoroborates have been prepared. The effect of 1 :1 and 1:2 metal to ligand reactant ratios have been examined. The complexes have been characterized on the basis of their analytical data, magnetic susceptibility, electronic and IR spectral ...
ABSTRACT Osun River is important for domestic, recreational and other activities. It flows along a channel that may be polluted by inputs from industrial, agricultural and other anthropogenic activities thereby limiting its normal use for drinking, fishing, recreation and other purposes. Available literature on the river quality is limited in scope, frequency of sampling and duration of studies. Therefore, a study of the river and its tributaries was carried out to determine the spatial and t...
Abstract - Chemical analysis and nutritional assessment of defatted Garcinia mangostana seeds (DGMS) were undertaken to determine its suitability as an additive at 0.00g, 18.00g, 36.00g, 54.00g and 72.00g inclusion levels in diets and performance of Clarias gariepinus post juveniles. Proximate analysis of DGMS showed that the defatted seeds were high in carbohydrate (71.00 ± 0.79%) but low in protein content (8.10 ± 0.22%). The mineral element analysis detected different minerals with potas...
ABSTRACT The release of Polycyclic Aromatic Hydrocarbons (PAHs) and phthalates from anthropogenic sources into the aquatic environment is of public health concern. The C18 bonded silica and styrene-divinyl-benzene polymer adsorbents which are used for preconcentration and remediation of PAHs and phthalates polluted water are expensive and non-biodegradable. Hence, there is need to source for alternative adsorbents. Starch and cyclodextrin based polymers have been reported to be cheap and biod...
ABSTRACT Heavy metal contamination in soil may be reflected in food crops due to plant uptake and such crops when consumed may cause adverse health effects. The assessment of toxic metal burden of soils and the capacity of food crops to accumulate these metals are essential. Such studies have not been reported in literature for Kogi State, a state noted for intense agricultural activity. The aim of this study was to determine heavy metals in soils, food crops, irrigation waters and sediments ...
ABSTRACT Titanium Oxide (TiO2) as a photocatalyst produces free radicals upon receiving light energy; thus, it possesses antibacterial properties. The antibacterial property of silvernanoparticles-doped TiO2 photocatalysts (Ag-NPs/TiO2) could be further enhanced by visible light illumination, which also widens its practical applications. However, the major limitation of this Ag-NPs/TiO2 composite material is its poor miscibility, which subsequently reduces the antibacterial activities of the...
ABSTRACT In this study, a series of N-pyridin-3-yl substituted [phenylsulphonamido] acetamide has been synthesized. The reaction of phenylsulphonyl chloride with various amino acids in basic medium yielded phenylsulphonamido alkanoic acid which, on chlorination with thionyl chloride, gave acid chloride derivatives of phenylsulphonamido alkanoic acid in situ. The acid chloride derivatives on condensation with 3-aminopyridine gave corresponding acetamide in good to excellent yield. The compoun...