The level of Cd, Co, Cu, Mn, Ni, Pb and Zn in fish and sediments of Rivers within the Kaduna South Jndustrial Zone were determined by flame atomic absorption spectrophotometry. The HN03 - I-1202 digestion .. .. system was used to digest the fish sample far trace m etals determination. Tire HN03 - H202 digestion method gave good recoveries which vCiries within 80-95% for Cd, 85-97% for Co, 81-99% for Cu, 79-97% for Mn, 81-93% for Ni, 87- 98% for Pb Clnd 77 - 98% for Zn in a fish smnple. T...
Human dietary intake comprises three macronutrients (protein, carbohydrate, and lipid) and a large number of micronutrients (vitamins, minerals, antioxidants, etc.). Good health rest, in part, on an adequate and balanced supply of these components to the human body [1 ]. Supplies and consumption of oils and fats are generally described in terms of seventeen commodity oils, four of 'which are of animal origin and the remainder of which are derived from plants. This description does not i...
ABSTRACT Cochlospernum tinctorium A. Rich was investigated for its chemical constituents and its antiplasmodial activities. The chemical constituents of petroleum ether, dichloromethane and ethyl acetate extracts of the rhizome of the plant were successively studied. The in vitro antiplasmodial activities for petroleum ether, dichloromethane, ethyl acetate, ethanol and water extracts as well as the isolated compounds were determined. Three compounds isolated from the dichloromethane extract ...
ABSTRACT Malaria and tuberculosis (TB) though curable and preventable, remain serious public health problems globally, with devastating consequences. Co-infection of these two deadly diseases worsens the situation and particularly makes treatment very difficult. While the current mainstay for malaria treatment, artemisinins, may gradually lose their potency due to the development of resistance by P. falciparum, M. tuberculosis has developed Multi-Drug Resistance (MDR) and Extensive Drug Resis...
ABSTRACT This study was conducted to assess the levels of heavy metal contaminations within the Weija dam area of the Weija Lake. Sediments, water and fish samples were taken from ten different sites within the Weija dam in March, 2014 (dry season) and August, 2014 (wet season). The sediment, water and fish samples were analysed for Hg, Se, Fe, Cd, Mn and Pb using Atomic Absorption spectroscopy (AAS). Mercury was determined using a cold vapour technique with the AAS equipped with hydride ge...
ABSTRACT The possession, use, cultivation, sale and trafficking of any form of cannabis in Ghana without lawful authority is illegal. Incidentally the substance remains one of the most abused in the country. The aim of this research was to measure the content of three major cannabinoids - THC, CBN and CBD in cannabis samples cultivated and abused in Ghana. The research was encouraged to fill this gap of information against the backdrop of the current social outcry on the legalization of the s...
ABSTRACT N-a-tosyl-L-lysyl-chloromethyl ketone (TLCK) has been coupled to ara-C or colchicine encapsulated liposomes via glutaraldehyde treated liposomal phosphatidylethanolamine (Lp-G-TLCK) or sodium metaperiodate oxidized oligosaccharide side chain of liposomal digoxin (Lp-D-TLCK). TLCK has been shown to react with specific histidine residue at the active site of such protein as trypsin and has high binding affinity for simian virus 40 and polyoma virus transformed fibroblasts. A 20-minute ...
ABSTRACT The use of raw maize cob (rmc) and activated maize cob (amc) as a low-cost natural adsorbent for the removal of Pb2+ and Cu2+ ions from simulated waste water was studied. Batch experiments were conducted to determine the effects of varying contact time, initial metal ion concentration, adsorbent dosage, pH and temperature of adsorption on adsorption equilibrium quantity (qe ) and percentage removal (% R). % R increased with increasing adsorbent dosage for the two metal ions. It also...
This project is concerned with the development and evaluation of an atom trapping technique for determination of heavy metals in environmental samples. Modified atom-trapping technique using fabricated nickel tube/sample holder (crucible) was employed to increase the sensitivity of a flame atomic absorption spectrometry.MBasic performance data for different parameters, such as burner height and the height of the support, were studied. Different designs and ways of placing the atom trap ov...
I he \orld population has been on the 1m.:rcase. I he cLnTcnt growth 1 i.liL I
ABSTRACT Organochlorine Pesticides (OCPs) are cyclic chlorinated hydrocarbons that are toxic and can bioaccumulate in the environment. Although, its usehas been prohibited in many countries including Nigeria; nevertheless they are still used extensively for pests control by cocoa (Theobroma cacaoL.) farmers in Nigeria. In addition, OCPs residual concentrations among other factors in cocoa bean influences their price in the World market. Therefore, this study was designed toassess the persist...
ABSTRACT This study was conducted to assess the extent of Mercury (THg) contamination at four locations within the Shama-Mporhor Wassa catchment area of the Lower Pra River. Water, fish and sediment samples were taken twice with the longitudinal transect method at Daboase, Beposo, Bokorkope and Shama during the minor rainy season in October and at the apex of the dry season in March. Careful investigation of the Shama-Mporhor Wassa catchment area revealed that two of the locations Daboase a...
ABSTRACT This research investigated the efficacy and chemistry of selected traditional medicines (TM) used in the treatment of schistosomiasis and also explored their antitrypanosomal potential. Crude extracts were obtained by successive extraction of dried herbs with dichloromethane and methanol while aqueous herbal preparations were extracted with dichloromethane and butanol. Biological activity was conducted by screening the crude extracts against the schistosomula (NTS) and adult worms of...
ABSTRACT Inherited Glucose-6-Phosphate dehydrogenase (G6PD) deficiency in humans results in hemolytic anaemia. The enzyme G6PD provides a crucial link in a series of biochemical reactions which occur in the red blood cell that leads to the steady state accuralation of NADPH, reduced glutathione by glutathione reductase, and the removal of potentially dangerous organic peroxides which, if not scanvenged, may result in the formation of radical species of oxygen which damage the energy generatio...
ABSTRACT The CysF9[93]β sulphydryl group is an indicator for tertiary and quaternary structure change in haemoglobin. Allosteric effectors such as proton and inositol hexakisphosphate (inositol-P6) influence its reactivity. This work was undertaken to study the effects of inositol-P6 and pH on the kinetics and equilibrium of the reaction of CysF9[93]β of dog (Canis familiaris) and donkey (Equus asinus) haemoglobins with 5,5'-dithiobis(2-nitrobenzoate) (DTNB). The number of sulphydryl groups...