ABSTRACT Multiwalled carbon nanotube (MWCNT) has been found to produce structural changes in Calf Thymus-DNA (CT-DNA). The interaction or binding of the multi-walled carbon nanotubes (MWCNT) was investigated in order to discover if it brings about any significant changes of the DNA double helix using CD spectra of the CT-DNA at two concentration levels of MWCNT representing an increasing MWCNT/DNA molar ratio. In addition, spectrophotometric titrations between MWCNT and CTDNA were carried ou...
ABSTRACT In the first part of this thesis, a brief survey of the chemistry of veratramine viz. its occurrence, isolation and structural diagnosis is given. This part also includes a review of recent work on the stereochemistry and the synthetic work of other workers on the alkaloid. The main section describes three approaches to the synthesis of the C-Nor-D-homo ring system of the veratrura alkaloids. Howell and Taylor’s acétate diester 6(3-acetoxy-1 p:2adi (methoxy carbonyl methyl)-9P~me...
ABSTRACT This research was conducted to detennine the levels of mercury, cadmium and zinc in the leaves of Xanthosoma sagittifoliwn (kotombre), Marlihot esclIlenta (cassava leaves) and the conn of Colecasia esclIlenta (taro conn) growing in the mining communities of Tarkwa, Prestea, Bankyim and Agona Junction. The Random sampling method was used to collect the samples and the wet digestion method was used to digest the samples for AAS analysis. A statistical analysis of the results of the res...
ABSTRACT Twenty-six wound healing plants have been identified in the Kpando Traditional Area in Ghana. The methanol extracts of six of these plants showed some level of antimicrobial activity against wound causing infectious microorganisms. Similarly, four of these plants exhibited significant wound healing properties. Free radical scavenging activity by 1, 1-diphenyl-2-picryl hydrazyl radical (DPPH) indicated a concentration dependent activity with no significant difference from Ascorbic aci...
ABSTRACT The roots of Cryplo/epis sangllino/Cllla have been investigated for their chemical compounds since 1931. But so far, not much has been reported on the stem although they are used in traditional medicine in Ghana. OJ'plo/cpis sallgllino/enla (Lind.) Schlechter (family Periplocaceae) is a medicinal plant used in some African countries against infectious and parasitic diseases. Phytochcmical $creening of the extracts from the stem (bark and wood) of Oyplo/epis sangliino/Cllla revealed t...
ABSTRACT The root bark of the plant Turraea heterophylla belonging to the family Meliaceae was investigated for its chemical constituents. Phytochemical screening of both the methanolic and methylene chloride extracts indicated the presence of tannins, saponnins, terpenes, steroids and about eight different limonoids. Exhaustive extraction, chromatography and spectral analyses led to isolation of three compounds. The spectrometric analyses and the resulting data - including IR, NMR(H-H COSY a...
ABSTRACT The iodine status of staff and pupils of Hillcrest Schools, undergraduates of UCC, 2016/2017 academic year and a household in Agona Swedru were determined using Titration Method, Sandell-Kolthoff Method and a Novel Method. Discriminant analysis results showed that the Novel Method correctly classified 77.4% of the original cases. The novel also had a percentage recovery of125% and a Horwitz Ratio of 0.12. Based on these, ...
Abstract This study includes phytochemical screening, quantification of secondary metabolites, thin-layer chromatography (TLC) and antimicrobial assay of African peach (Sarcocephalus latifolius). The phytochemical analysis revealed the presence of alkaloid, flavonoid and saponin at various quantities with saponin more abundant amongst others like tannin, glycoside and phenols that are present. All the extracts were tested for antimicrobial activity with ethanol extract and water extract...
Abstract Development of improved methods for the synthesis of copper nanoparticles is of high priority for the advancement of material science and technology. Herein, starch-protected zero-valent copper (Cu) nanoparticles have been successfully synthesized by a novel facile route. The method is based on the chemical reduction in aqueous copper salt using ascorbic acid as reducing agent at low temperature (80 °C). X-ray diffraction, scanning electron microscopy and energy-dispersive X-ray spe...
CHAPTER ONE 1.0 INTRODUCTION Bioactive plants are commonly used by traditional healers or in folklore medicines for the relief of pain or some alignments. This act of medication has made some plant families popular (Heinrich 2000; Kuete et al., 2006).The acceptance of traditional medicine as an alternative form of health care has assisted scientists in elevating these claims, by studying the chemical composition and biological potential (Bisignano et al., 1996; Hammer et al., 1999). This ...
Abstract: This present study deals with the quantitative and qualitative phytochemical screening, the antimicrobial properties and thin layer chromatography of Lavandula angustifolia leaves extracts. These were achieved using the cold maceration method of extraction involving hexane, water (aqueous) and ethanol, to ensure that a wide polarity range of components are extracted. Alkaloid, phenol, flavonoids, tannins, terpenes, glycosides and steroids were observed present in the leaves ...
Abstract: For every heteronuclear molecule, protonation can occur at more than one site thus giving rise to more than one proton affinity. Experimentally, only one proton affinity (PA) value is reported for a molecule and the experiment does not specify the site for the protonation. In the present work, quantum chemical calculations are carried out on SiF4 and its possible protonated analogues (HF4Si+ and HSiF4 + ) by employing several computational chemistry methods including the M...
Cellulose is the most common structural biological organic compound on Earth which is widely used in paper and textile industries and urea-formaldehyde resin is a thermosetting plastic used mostly as adhesives for plywood, particleboard and other structured wood products. Natural fiber composites are realistic alternatives of glass fiber composites. Using urea-formaldehyde, resorcinol-formaldehyde, phenol-formaldehyde, saturated polyesters as matrixes and natural fiber as reinforcem...
Cellulose is the most abundant, structural, biological organic compound on Earth which is widely used in paper and textile industries. In this project work, the blend of compressive character of Urea-Formaldehyde Resin with addition of Cellulose is tested. Cellulose can be extracted from dried plant by alkaline treatment (mercerization), followed by neutralization with acid; product of which undergoes bleaching to produce pure form of cellulose. Urea Formaldehyde Resin c...
The variation of character of urea formaldehyde resin with addition of cellulose extracted from corn husk was tested. Cellulose was extracted from dried raw corn (Zea mays) husk, the second largest agricultural crop grown around the world, by alkaline treatment (mercerization), followed by neutralization with acid; product of which underwent bleaching to produce pure form of cellulose. Urea-formaldehyde (UF) resin was prepared by heating the formaldehyde in paraffin oil bath and adding urea t...