Abstract
Background: Evaluation of the medicinal uses of plants remains a growing field of research. This study investigated the effects of Eucalyptus globules on alloxan -induced diabetic rats.
Materials and Methods: Thirty male albino rats were randomized into 5 groups (n=6).Group A served as the control and was maintained on standard rat chow and water ad’libitum. Diabetes was induced in Group C, D and E animals by intraperitoneal administration of alloxan monohydrate (150 mg/kg).Groups B and D were orally administered with aqueous extract of Eucalyptus globulus at a dose of 150 mg/kg per oral daily for 4 weeks, while group E received glibenclamide at a dose of 0.6 mg/kg orally in addition. Fasting plasma glucose, antioxidant status (catalase and xanthine), malondialdehyde (MDA), liver function enzymes (AST and ALT) and bicarbonate ion (HC0 3 - ) were assessed after 4 weeks.
Results: Aqueous extract of Eucalyptus globulus leaves significantly reduced fasting plasma glucose level, MDA, HC0 3 - , and liver enzymes ( P
NWABUZOR, E. (2018). Hypoglycemic and Antioxidant Potentials of Aqueous Extract of Eucalyptus Globulus in Experimentally-Induced Diabetic Rats. Afribary. Retrieved from https://afribary.com/works/hypoglycemic-and-antioxidant-potentials-of-aqueous-extract-of-eucalyptus-globulus-in-experimentally-induced-diabetic-rats
NWABUZOR, EMMANUEL "Hypoglycemic and Antioxidant Potentials of Aqueous Extract of Eucalyptus Globulus in Experimentally-Induced Diabetic Rats" Afribary. Afribary, 15 May. 2018, https://afribary.com/works/hypoglycemic-and-antioxidant-potentials-of-aqueous-extract-of-eucalyptus-globulus-in-experimentally-induced-diabetic-rats. Accessed 07 May. 2024.
NWABUZOR, EMMANUEL . "Hypoglycemic and Antioxidant Potentials of Aqueous Extract of Eucalyptus Globulus in Experimentally-Induced Diabetic Rats". Afribary, Afribary, 15 May. 2018. Web. 07 May. 2024. < https://afribary.com/works/hypoglycemic-and-antioxidant-potentials-of-aqueous-extract-of-eucalyptus-globulus-in-experimentally-induced-diabetic-rats >.
NWABUZOR, EMMANUEL . "Hypoglycemic and Antioxidant Potentials of Aqueous Extract of Eucalyptus Globulus in Experimentally-Induced Diabetic Rats" Afribary (2018). Accessed May 07, 2024. https://afribary.com/works/hypoglycemic-and-antioxidant-potentials-of-aqueous-extract-of-eucalyptus-globulus-in-experimentally-induced-diabetic-rats