ABSTRACT
The embryotoxicity potentials of normal dosage regimens of chloroquine used for therapeutic purposes were assessed in this research. Accordingly, five dosage regimens ^ . 5 ,10;0 12.5 15;0 and 20;0®g/kg body weight)=0f chtorocjuine diphosphate were screened by the High Performance Liquid Chromatography (HPLC) method to select those, which will provide whole blood levels: m the (Sprague-Dawley) rats comparable to those achievable during therapeutic use. The dosages of 7.5, 10,0 and 12.5 mg/kg body weight produced peak levels of 1,811,80 ng/ml (3.5 pM> lj688.34 ng/ml
II, S (2021). Invivo Assessment of The Embryotoxicity of Chloroquine in The Rat. Afribary. Retrieved from https://afribary.com/works/invivo-assessment-of-the-embryotoxicity-of-chloroquine-in-the-rat
II, SAMUEL "Invivo Assessment of The Embryotoxicity of Chloroquine in The Rat" Afribary. Afribary, 12 Apr. 2021, https://afribary.com/works/invivo-assessment-of-the-embryotoxicity-of-chloroquine-in-the-rat. Accessed 16 May. 2024.
II, SAMUEL . "Invivo Assessment of The Embryotoxicity of Chloroquine in The Rat". Afribary, Afribary, 12 Apr. 2021. Web. 16 May. 2024. < https://afribary.com/works/invivo-assessment-of-the-embryotoxicity-of-chloroquine-in-the-rat >.
II, SAMUEL . "Invivo Assessment of The Embryotoxicity of Chloroquine in The Rat" Afribary (2021). Accessed May 16, 2024. https://afribary.com/works/invivo-assessment-of-the-embryotoxicity-of-chloroquine-in-the-rat