MODELING CHOLERA DYNAMICS WITH CONTROLS

ABSTRACT.

In this paper, we present and analyze a cholera

epidemiological model with control measures incorporated. This

model is extended from the one proposed in [16] by including

the effects of vaccination, therapeutic treatment, and water san-

itation. Equilibrium analysis is conducted in the case with con-

stant controls for both epidemic and endemic dynamics. Opti-

mal control theory is applied to seek cost-effective solution of

multiple time-dependent intervention strategies against cholera

outbreaks.

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