Phytochemical And Biological Studies On Commiphora Africana (Burseraceae) Root

ABSTRACT

The ethanolic extract (crude extract) was successively extracted with nhexane,

chloroform, water, 103 aqueous methanol and n_hexane to give the

corresponding fractions. The crude exfract, 103 "aqueous methanol, vvater

soluble and n-hexane fractions of the root of .c_.africana, were screened for

antimicrobial activity and chemical constituents. The n-hexane fraction was

chromatographed on a column of silica gel to give a number of fairly pure

components. The infrared spectra of the components indicated the presence

of hydroxyl, esters, carboxylic and aromatic functional groups. The root Vas

found to be active against Staphvlococcus aureus, Escherichia coli, Candida

albicans and Bacillus subtilis. The components were also found to be active

against Staphylococcus aureus, Escherichia coli, Candida albicans, Bacillus

subtilis and Pseudomonas aeruginosa.

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