Studies On The Relationship Between Some Trace Elements And Steroid Hormones In Prostatic Disorders Amongst Nigerians

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ABSTRACT

Benign hyperplasia and Carcinoma of prostate are pro static disorders commonly found in aging sales. These disorders are reported to be less common amongst Nigerians, though there has been no concrete pathophysiological evidence to support this observation. The exact aetiology of these disorders has not been resolved, but some factors have been identified as being contributory to their development. Amongst these factors are androgenic hormonal control and the influence of some trace-elements on the metabolic activities of the gland.

We investigated the interrelationship between these factors in Nigerians with a view to elucidating any physiological differences that may exist between Nigerians and other peoples. Our results showed that the extracellular hormonal millieu of the prostate gland in Nigerians is not significantly different from those of Caucasians in Europe and North America. 

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