ABSTRACT
The usefulness of non-steroidal anti-inflammatory agents in the management of rheumatoid diseases cannot be over-emphasized. As this disease is characterized by chronic inflammation, it is usual to test compounds for anti-inflammatory activity in animals and then hope that the active ones should be clinically useful as anti-rheumatic drugs, From the literature, non-steroidal anti-inflammatory agents have covered a wide range of chemical structures aryl acetic, aryl-propionic, arylbutyric and anthranilic ' acid derivatives, Other compounds including the benzothiazines are also known to be potent agents. This work involved the synthesis of some amino methyl derivatives of 2-naphthol and screening them as potential anti-inflammatory agents. These derivatives from the point of view of their electronic and stereochemical characteristics are considered to be similar to the known bis(2-hydroxynaphthy1)- methane derivatives, earlier L'G+UL led iu ilave pronounced anti-inflammatory activity, The physicochemical properties of these compounds were .also determined in an effort to correlate observed biological activity and chemical structure.
Consults, E. & John, M (2023). Synthesis and Anti-Inflammatory Properties of Aminomethyl Derivatives of 2 Naphthol. Afribary. Retrieved from https://afribary.com/works/synthesis-and-anti-inflammatory-properties-of-aminomethyl-derivatives-of-2-naphthol
Consults, Education, and MBAH John "Synthesis and Anti-Inflammatory Properties of Aminomethyl Derivatives of 2 Naphthol" Afribary. Afribary, 27 Apr. 2023, https://afribary.com/works/synthesis-and-anti-inflammatory-properties-of-aminomethyl-derivatives-of-2-naphthol. Accessed 11 May. 2024.
Consults, Education, and MBAH John . "Synthesis and Anti-Inflammatory Properties of Aminomethyl Derivatives of 2 Naphthol". Afribary, Afribary, 27 Apr. 2023. Web. 11 May. 2024. < https://afribary.com/works/synthesis-and-anti-inflammatory-properties-of-aminomethyl-derivatives-of-2-naphthol >.
Consults, Education and John, MBAH . "Synthesis and Anti-Inflammatory Properties of Aminomethyl Derivatives of 2 Naphthol" Afribary (2023). Accessed May 11, 2024. https://afribary.com/works/synthesis-and-anti-inflammatory-properties-of-aminomethyl-derivatives-of-2-naphthol