THE CHEMISTRY OF SOME EXTRACTIVES FROM PLANTS OF THE FAMILY RUTACEAE

ABSTRACT

Chemically, the Rutaceae family is probably the most versatile of all higher family of plants. Three main groups of compounds, namely, limonoids, coumarins and quinoline alkaloids have been obtained from this family. The LLtroductory part of this work reviews very briefly the chemistry of each of these groups.

In the main work, three plants of the West African genera of the Rutaceae were investigated. The wood of Afraegle paniculata (Schum and Thonn) yielded the furocoumarLD, imJ£eratori~ which has isolated earlier from a number of Rutaceous plants and in addition, a furoquinoline alkaloid, dictamnine which had also been isolated from a large number of other genera of the family. The root of Clausena anisata was shown to contain imperatorin along with a new coumarin (couli1arrayin)which was shown almost at the same time byDreyer to be a consti tuent of Murraya paniculata.

From the woocl of Oricia suaveolens Yvas isolated a new alkaloid related to Flindersine (an alkaloid from an Australian Rutaceae plant)

The structure of the new alkaloiciuas elucidated from spectroscopic studies to be 1-methyl-6,7-dimethoxy-flinderslnc and this structure was confirmed synthetically.