ABSTRACT Erythromycin is antibiotics produced from a strain ofStreptomyces erythreus (later changed to "Saccharopolyspora erythraea") which belongs to the group of macrolides which tends to inhibit the growth/development of bacteria. It sometimes exhibits bactericidal characteristics when administered in high concentration. It carries out its bacteriostatic actions by binding to the 23s RNA component of the 50s ribosome of the bacteria, thereby interfering with the assembly of the 50...
ABSTRACT Staphylococcus aureus is one of the most important and studies gram-positive bacterial strains, which have a great potential to infect human being as well as other mammals. Staphylococcus aureus is a major cause of infections responsible for much life threatening diseases like toxic-shock syndrome, staphylococcal scarlet fever, meningitis, osteomyelitis etc. infection due to these strains are difficult to treat. This research work focused on the identification of drug target enzymes...
ABSTRACT Background: Tuberculosis has become a global burden and of public health importance. Health care workers in developing countries are highly susceptible to workplace associated TB infection due to the long hours spent with patients who have undiagnosed or untreated TB cases, poor infection control measures and poor isolation of TB cases in health care facilities. Objective: To assess the implementation of tuberculosis infection control measures among health care workers at the Great...
ABSTRACT Innate immunity has a key role in the control of microbial infections in both vertebrates and invertebrates. In insects, including vectors that transmit parasites that cause major diseases such as trypanosomosis, leishmaniasis and filariasis, antimicrobial peptides and agglutinins form an important component of innate immunity and participate in regulating parasite development. In this study, induced haemolymph peptides from a non-vector, nonheamatophagous insect, Schistocerca grega...
ABSTRACT Serological and bacteriological studies were carried out to determine the prevalence of brucellosis among cattle in Benue State, Nigeria; and to determine the level of contamination of fresh bulk herd and fermented milk sold to the public for consumption; as well as detect and characterize the causative agent of bovine brucellosis in the area; and to evaluate a new diagnostic test for brucellosis, the Brucella Lateral Flow Assay (the rapid field test). Serum samples obtained from ca...
ABSTRACTNetwork Virus are programs designed to destroy or hamper some function of the computer. By doing this they either destroy information or slow down processing capabilities of the computer system. In recent years they have also had a destructive presence on computer networks and on the internet.Many people do not understand what is a computer virus? In computing terminology it is a self replicating/self producing automated program. This program spreads by inserting itself into executabl...
The Livestock sector in Ghana has incurred significant losses due to the African Animal Trypanosomiasis (AAT), transmitted by tsetse flies. Attempts to reduce the disease prevalence have been mainly through vector control and the use of trypanocidal drugs. An assessment of these control measures gives appreciable information on the impact of the efforts involved in such activities.This study was therefore firstly to identify a trypanosomiasis endemic area where trypanocidal drugs are use...
ABSTRACT The pork tapeworm (Taenia solium) is an important parasite that causes disease in humans and pigs where humans host the adult worm in the small intestines and the larval stages are found in the muscles, brain and other tissues in humans and pigs (cysticercosis). Neurocysticercosisis (where the larva of Taenia solium is in the brain) is a major cause of epilepsy in humans. Humans can get the infection by consumption of infected pig meat while consumption of food and water contaminated...
ABSTRACT Topic: Assessment of factors contributing to the prevalence of puerperal sepsis among mothers attending the obstetrics Ward at FortPortal regional referral hospital, western Uganda. Background: Puerperal sepsis is one of the leading causes of preventable maternal morbidity and mortality. It is still ranked as 3rd major cause of maternal death in our country. Aim: The objective of this study was to assess the factors that predispose a mother to the development of puerperal sepsis, to ...
Abstract Cryptosporidium, a protozoan parasite that causes gastrointestinal illness, is transmitted by ingestion of oocysts excreted in human or animal stools. Cryptosporidiosis presents with severe diarrhoea in HIV/AIDS patients and self-limiting in immunocompetent individuals. The parasite is yet to receive sufficient public health attention in Nigeria. This study was undertaken to investigate association of Cryptosporidium oocysts with other intestinal parasites in patients with gastrointe...
ABSTRACT Survival analysis is a method for analysing the occurrence of a given event. This research seeks to evaluate the survival of HIVIAIDS, TB and co-infected patients and to identify the major prognostic factors that influence their survival. In this study, survival data for HIV/AIDS, TB and HIVITB co infection patients were obtained from St. Mathias Hospital in Yeji, Pru District of Brong Ahafo Region of Ghana. The data was fitted using both the Cox model and accelerated failure time mo...
ABSTRACT Few reports could be found on screening, isolation and characterisation of enzymes in local Fauna and Flora and little is known about laccase enzymes from Namibia origin hence there is a niche for enzyme studies in this area. This research has qualitatively screened Termitomyces schimperi and Kalaharituber pfeilii fruiting bodies for laccase enzymatic activity using α-naphtnol and 2, 2-azino-bis 3-ethylbenzthiazoline-6-sulphonic acid (ABTS). A clone of T. schimperi was also grown in...
ABSTRACT Infection with Rubella virus is a public health concern because it may lead to serious consequences such as Congenital Rubella Syndrome (CRS) during early pregnancy. Introduction of the rubella virus vaccine in developed countries has since informed the need to assess the prevalence of rubella in the African countries and determine whether it is necessary to introduce a vaccine. This study, therefore, was carried out to determine the seroprevalence of the rubella infection in expecta...
ABSTRACT Background: Hawkers constitute mobile population who are at increasing risk of being infected with malaria. They move around the city to carry out their duties. Most of them have no accommodation. They sleep wherever they find themselves in the evening and do not benefit from most of the malaria intervention programs such as the use of long lasting insecticide net. Objectives: The objective of this study was to determine factors associated with malaria infection among hawkers in the ...
ABSTRACT A study was conducted in a glasshouse at Sokoine University of Agriculture Morogoro, Tanzania to investigate the effect of coffee pulp compost (CP), Minjingu phosphate rock (MPR) and coffee pulp composted with Minjingu phosphate rock (CPMPR) on phosphorus availability and response of Tomato (Lycopersicon esculentum M.) var. Carl J in 3x8 completely randomized block design experiment. The P sources were applied on a P deficient Chromic Acrisol at eight equivalent rates of 0, 40, 80, ...