Abstract/Overview
2-Hydroxy-4-methoxybenzaldehyde (1), a compound isolated from Mondia whytei (Hook) Skeels (Asclepiaceae) roots exhibited larvicidal activity (LD5022 mg/mL). A total of 18 other derivatives and closely related congeners revealed varying levels of larvicidal activity. Several closely related congeners, like 2-benzyloxy-4-methoxybenzaldehyde (2), 2-hydroxybenzaldehyde (12), 2-benzyloxybenzaldehyde (3) and benzylphenyl ether (4), showed marked improvement in activity (LD5010, 9, 4.8, 1.2 mg/mL, respectively) against Anopheles gambiae larvae. 2-Benzoyloxy-4-methoxybenzaldehyde (5) exhibited similar activity level (LD50 28 mg/mL) as 1.
M., M (2024). 2-Hydroxy-4-Methoxybenzaldehyde: larvicidal structure-activity studies. Afribary. Retrieved from https://afribary.com/works/2-hydroxy-4-methoxybenzaldehyde-larvicidal-structure-activity-studies
M., Mahanga "2-Hydroxy-4-Methoxybenzaldehyde: larvicidal structure-activity studies" Afribary. Afribary, 04 Jun. 2024, https://afribary.com/works/2-hydroxy-4-methoxybenzaldehyde-larvicidal-structure-activity-studies. Accessed 04 Dec. 2024.
M., Mahanga . "2-Hydroxy-4-Methoxybenzaldehyde: larvicidal structure-activity studies". Afribary, Afribary, 04 Jun. 2024. Web. 04 Dec. 2024. < https://afribary.com/works/2-hydroxy-4-methoxybenzaldehyde-larvicidal-structure-activity-studies >.
M., Mahanga . "2-Hydroxy-4-Methoxybenzaldehyde: larvicidal structure-activity studies" Afribary (2024). Accessed December 04, 2024. https://afribary.com/works/2-hydroxy-4-methoxybenzaldehyde-larvicidal-structure-activity-studies