ABSTRACT There had been a concern over the rising cases of emerging issue like drug and substance, abuse, adolescent pregnancy, abortion, poor performance, truancy, absenteeism, suicide, dropout, HIV and AIDS prevalence among students in secondary schools. This called for the need to investigate or assess the effective implementation of Life Skills Education curriculum in public secondary schools in Uriri and Awendo districts in Migori County. LSE is aimed at equipping the learners with psych...
Abstract This study is about the prevalence, causes and effects of psychoactive drug use among students at Midlands State University. The chapter introduces the whole study by discussing the following issues: the background of the study, statement of the problem, significance of the study, purpose of the study, objectives, hypotheses, delimitations of the study, limitations of the study, assumptions and effective definitions of key terms.
ABSTRACT Background: One of the consequences of drug resistance to malaria parasites, is poor haematological recovery (Bloland et al., 1993; Verhoeff et al., 1997; Ekvall et al., 1998). Use of the right antimalarial is the key to avert this situation. Few studies have explored sex differences of these drug interventions in pediatric populations. ( Domellöf M et al 2002 and Songül S et al 2009). Methods: This study is a descriptive study analyzing secondary data collected from a primary c...
ABSTRACT This study evaluated the antilipidemic activity of water extracts from leaves of Desmodium velutinum on albino wistar rats. The phytochemical analysis of the leaf extract showed the presence of tannins, saponins, alkaloids, soluble carbohydrates, flavonoids, reducing sugar, steroids, cyanide and terpenoids. The animals were treated with known drugs (atorvastatin 2ml). There were significantly reductions in HDL 13.00 1.41 mg/dl LDL 1.20 0.14 mg/dl and triglyceride 39.00 0.14 mg/...
ABSTRACT Background: The problem of orphans is sensitive all over the world and causes challenge in caring and protection of their right and prosperity (UNICEF, 2017a). This study, intended to determine the effect of orphan institutionalization on child deprivation, child maltreatment and quality of life among the orphaned children in Zanzibar. Methods: Analytical cross-sectional study design was employed. Simple random sampling was used to select 374 participants from all five regions of Zan...
ABSTRACT Tropical starches from Dioscorea dumetorum (bitter) and Dioscorea oppositifolia (Chinese) yams were acetylated with acetic anhydride in pyridine medium and utilized as polymers for the delivery of repaglinide inmicrosphere formulations incomparisonto ethyl cellulose.Acetylatedstarches of bitter andChinese yams with degrees of substitution of 2.56 and 2.70 respectively were obtained. Acetylation was confirmed by FTIR, 1H NMR spectroscopy. A 32 factorial experimental design was perform...
ABSTRACT As the use of antiretroviral therapy becomes more widespread across Africa, it is imperative to characterise baseline molecular variability and sub-type specific peculiarities of drug targets in non subtype B HIV-1 infection.
ABSTRACT The study was aimed at evaluating the antidiabetic potentials of Anogeissius leiocarpus DC Guill and Perr root bark methanol, ethanol and ethanol plus trona extract; and preparing, characterizing and evaluating lipospheres as drug delivery system loaded with A.leiocarpus root bark methanol extract. 400 mg/kg of methanol,ethanol and ethanol plus trona extracts of the A.leiocarpus root bark extracts were used in preliminary evaluation of antidiabetic effect of this plant root bark extr...
ABSTRACT Milk is an important source of nutrients to human and animals, but due to its high water activity and nutritional value it serves as an excellent medium for growth of many kind of microorganisms under suitable conditions. The present cross sectional study was conducted to assess microbial quality of raw cow milk and to determine antimicrobial susceptibility of the selected common milk-borne bacteria in Kilosa and Mvomero districts, Morogoro region. A total of 56 respondents were inte...
ABSTRACT Human immunodeficiency virus or acquired immunodeficiency syndrome remains the leading cause of death in sub-Saharan Africa, Kenya being one of them. Over 407,000 patients were on antiretroviral therapy by the year 2015 nationally. Despite sustained clinical benefits associated to usage of antiretroviral drugs, adverse effects are emerging as a major safety concern. Some of the factors that have been identified as having an influence on the effect of ARV in disease control include a...
Despite the progress that has occurred in recent years in the development of therapy, there is still a need for effective and potent analgesics for pain. Pain is defined as unpleasant feeling essential for body‘s defense system. Pain is managed using analgesics such as aspirin,paracetamol, diclofenac, morphine, opioids, among others. Conventional antinociceptives are expensive and have many side effects. Continued use of these drugs may lead to tolerance. Medicinal plants have been use...
Indigofera lupatana Baker F. (locally known as Mugiti) has been used by Mbeere community of Kenya to treat cough, diarrhea, pleurisy and gonorrhea. These and other infectious diseases are a cause of morbidity and mortality in humans and animals. Their effects are further aggravated by drug resistance. There is also increased emergence and re-emergence of infections from previously harmless micro-organisms, as part of nosocomial and opportunistic infections. This calls for search of new d...
Herbal medicine has been widely used and forms an integral part of primary health care in most countries. Of late, despite emphasis being put in research of synthetic drugs; interest in medicinal plants has been reborn. This is due to the rapidly growing population, the failure of modern medicine to provide effective treatment, increase in chronic diseases and the emergence of the multi-drug resistant pathogens. It is of importance to establish a scientific basis for the use and validati...
ABSTRACT Urinary tract infections (UTI) are bacterial infections encountered in the hospital and community and is preventable. It is among bacterial infection encountered with increasing antibiotic resistance to uropathogens, although there is availability of antibiotics. Despite the wide spread of antibiotics, it remains the common bacterial infections. Antibiotic susceptibility testing therefore provides information that allows clinicians to select the most appropriate antimicrobial drugs. ...
Abstract: Concerns about disease causing bacteria are now ever increasing. The common and immediate action to these disease causing microbes is the use of antibiotics. However, due to the challenges of drug-resistance in bacteria and the problems of affordability of the drugs, the search for new compounds from plant and animal sources that act against the pathogens has become crucial in many countries. The aim of this study was to investigate the possibility of using honey, garlic and ginger...