Ginger or Zingiber officinale has been reported to possess antioxidant activities that can protect against free radical damage. We therefore carried out this study to investigate the possible ameliorative effects of ginger against the clastogenicity, hepatotoxicity and oxidative stress induced by nitrobenzene (NB) administration in wistar rats. Twenty male wistar rats were divided into four g...
One interesting branch of biochemistry which scientists are still trying to completely unravel is the area of chronobiochemistry. The history of chronobiology is dated 400 B.C., when Androsthenes observes that leaves of certain trees open during the day and close at night. It was only recently that the first human clock gene was discovered. All living organisms possess an internal bio...
ABSTRACT Background: Edible camphor (EC) is one of the ingredients in the preparation of local infusion for the management and treatment of pile, back pain, and erectile dysfunction, which are practices commonly in the south-western part of Nigeria. Methods: Thirty rats were used for the study, and were divided into six groups of five rats each. Group I animals served as normal ...
In living cells, especially eukaryotes, mitochondria involvement appears to be important in the general status of every aspect of life. Apoptosis as a programmed cell death is mandatory to all life process thus, mitochondria might be describe as organelles that serves as a gatekeeper to trap a variety of proapototic protein and prevent the functions of this proteins in the cytosol...
Plant transformation mediated by Agrobacterium tumefaciens, a soil plant pathogenic bacterium, has become the most used method for the introduction of foreign genes into plant cells and the subsequent regeneration of transgenic plants. This review focuses on the host recognition and the process of gene transfer from Agrobacterium tumefaciens to plant cells which implies several essential steps.
ABSTRACT The present study investigated the ameliorative properties of Diospyroschloroxylon (methanolic) leaf extract (DCLE) in liver of rats intoxicated with N-Nitrosodimethylamine (NDMA). Antioxidant markers- Superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and lipid peroxidation were assayed spectrophotometrically. DNA fragmentation was determined spectrophotometrically. The Bcl-2, Ki-67 and ...
Immunomodulatory Potentials of Ethanolic Leaf Extract of Phyllantus amarus in Wistar Rats Abstract The immunomodulatory effect of the ethanolic leaf extract of Phyllantus amarus on wistar rats was investigated. Twenty eight (28) male animals were used for the study. The animals were divided into four (4) groups of seven (7) animals each. Group 1 was the normal control and received distilled water, animals in group 2 were given low dose (7.1 mg/kgBW) of the extr...
ABSTRACT In order to investigate the effects of Yoyo and Swedish bitters on arylesterase activity in very low density lipoprotein (VLDL), 40 male albino rats were divided into 6 groups; i, 3-week Yoyo bitters. ii, 3-week Swedish bitters. iii, 3-week control. iv, 6-week Yoyo bitters. v, 6-week Swedish bitters, vi, 6-week control. Daily weight of animals were determined and dosage of bitters corresponding to weight of each animal was administered. VLDL was isolated by a simple precipitation pr...
ABSTRACT Ohaji Egbema, Imo State were studied over a period of twelve months to determine the effects of detergent effluent discharges on the aspect of water quality of the river. Water samples from Points A, B and C were screened for microbiological analysis. The results revealed that the level of pollution varied depending on season and that the water quality was acceptable at the upstream (Point A) but became impaired at Points B and C, indicating significant pollution from detergent ef...
ABSTRACT The global scenario is now supporting the development of modern drugs from less toxic plant products with proven medicinal properties. Each part of the neem plant (Azadirachta indica A. Juss) reportedly has various medicinal properties and has been in use in many continents for centuries. In this project work, water extract from Neem leaves (Azadirachta indica A Juss) with the modern atomic absorption spectrophotometer was presented. The mineral and chemical properties in the water ...
TABLE OF CONTENTS CHAPTER ONE INTRODUCTION 1.0 INTRODUCTION 1.2 AIMS AND OBJECTIVE CHAPTER TWO 2.0 LITERATURE REVIEW 2.1 HISTORICAL OVERVIEW 2.2 CONDITIONALLY PATHOGENIC 2.2.1 Intracellular 2.2.2 By location 2.2.3 Mechanisms of Bacterial Pathogenicity 2.3 The Underlying Mechanisms of Bacterial Pathogenicity 2.3.3.2 UTAZI (GONGRONEMA LATIFOLIUM) 2.3.3.3 CHEMICAL COMPOSITION OF ‘UTAZI’ (G. LATIFOLIUM) CHAPTER THREE 3.0 MATERI...
ABSTRACT The ethanolic leaves extracts of Hymenocardia acida was screened for anti-diabetic activity based on folklore and little or no work cited in literature. Hymenocardia acida (Family: Hymenocardiaceae) has a very high anti-diabetic potentials which appeared comparable to the control glibenclamide in alloxan induced diabetes mellitus. The study evaluated the ethanolic leaves extract of H. acida for anti-diabetic activity in a rat model of non-insulin dependent diabetes mellitus (NIDDM)....
Research and reviews are constantly being carried out in order to discover newer, and abundant plant sources of bioactive components which exhibit strong pharmacognostic and biochemical effects. The whole plant of Diodia sarmentosa has a folkloric reputation as an anti-ulcer agent. It is claimed to be useful in herbal medicine for the treatment of bacterial and fungal infections and some other ailments. The qualitative and quantitative analysis of some phytochemicals in Diodia sarmentosa (tro...
ABSTRACTThe Anatomy of this project write-up encompasses the ordinary look of enzymes as organic molecules; rather it sheds more light into the comprehensive view and determination of the catalytic and specific activity enzymes particularly-DIASTASE, MALTASE and zymase can exploit in industrial application, also critically important is the selective ways of providing fundamental data which allows the society-particularly small-scale brewers to understand and exploit the chemistry of fermentat...
THIS REPORT DETAILS WORK DONE BY A SIWES STUDENT OF BIOCHEMISTRY