ABSTRACT Nutritional and antinutritional content of ingredient used in preparing dambu were determined by proximate composition, vitamins, minerals and antinutritional contents analysis. Maize and Moringa flowers were used as the experimental samples and the work was conducted in triplicate which resulted in obtaining the experimental result in mean and standard deviation. Appreciable amount of nutritive composition were obtain in the used maize and Moringa samples. While the antinutritional...
ABSTRACT Kidney function parameters were evaluated in plasmodium berghei infected mice treated with crude methanol extracts of Azadirachta indica leaves in this study. A total of forty (40) male albino mice inoculated with quinine resistant strains of plasmodium berghei were randomized into nine (9) groups of (4) animals each while four additional mice serve as the uninfected control group. Group 1 was treated with tween 80, group 2 treated with 10mg/kg chloroquine while groups 3,4, and 5...
Diabetes mellitus is a syndrome characterized by chronic hyperglycemia and disturbances of carbohydrate, fat and protein metabolism associated with an absolute or relative deficiency in insulin secretion or insulin action. To investigate the effect of white grub extract on alloxan-induced diabetic rats. Diabetes was induced in rats after 18 hours of fasting intraperitoneally by alloxan (80 mg/kg). A total of 40 rats used, were divided into eight groups (G1- GVIII) of five rats each. GII-GVIII...
ABSTRACT Consumption of green tea (Camellia sinensis) may provide protection against chronic diseases, including cancer. Green tea polyphenols are believed to be responsible for this cancer preventive effect, and the antioxidant activity of the green tea polyphenols has been implicated as a potential mechanism. This hypothesis has been difficult to study in vivo due to metabolism of these compounds and poor understanding of the redox environment in vivo. Green tea polyphenols can be direct an...
This study sought to investigate the therapeutic effectof methanolic extract of Telfairia occidentalis leavesagainst acute ethanol-induced oxidative stress inWistar rats. Fresh plants of T. occidentalis werepurchased from Oja-Oba Market in Ibadan. Theleaves were dried and extracted using soxhletapparatus and methanol as the solvent. The methanolwas evaporated in a rotary evaporator at 35 oC witha yield of 2.31g representing a percentage yield of9.24%. Twenty adult male Wistar rats were used f...
Antihaemolytic effect of ethanolic leaf extract ofVernonia amygdalina in Wistar rats is the aim of thisstudy. Fresh plants of V. amygdalina were harvestedfrom the Institute of Agricultural Research andTraining, Ibadan. The leaves were carefully removedfrom the stem and washed in running water toremove contaminants. They were air dried at roomtemperature in an open laboratory space for 14 daysand milled into powder. The extraction was doneusing soxhlet apparatus and ethanol as the solvent.Etha...
Preventive and therapeutic activities of methanolicextract of Talinum triangulare leaves againstethanol-induced oxidative stress in wistar rats is theaim of this study. Fresh plants of T. triangulare werepurchased at a local market in Orita-Challenge,Ibadan. The leaves were dried and extracted usingsoxhlet apparatus and methanol as the solvent. Themethanol was evaporated in a rotary evaporator at35 oC with a yield of 2.76 g which represents apercentage yield of 11.04%. Twenty Wistar rats with...
Phaseolus vulgaris, Common Bean is a herbaceous annual plant grown worldwide for its edible dry seed (known as just "beans") or unripe fruit (green beans) and a member of the legume family Fabaceae. They are quite popular amongst the natives because of its high protein, minerals and vitamins content (Gentry et al., 1999). The use of a wide range of chemicals to destroy pests and weeds is an important aspect of agricultural practice in both developed and developing countries but there is a w...
ABSTRACT Coconut water is a natural nutritious beverage that contains several biologically active compounds. This study was set up to evaluate the antioxidant potential of coconut water. Twenty five adult male albino rats, used in this work, were grouped into five (A, B, C, D and E), of five rats per group. Groups A, B, C and D were administered orally with 0.5, 1.0, 1.5 and 2.0mg/kg body weight respectively of the coconut water for seven consecutive days. Group E was the control. Giutathion...
ABSTRACT Vegetables has been an integral part of day to day diet for so many people in Kenya. It is used in the form of raw fruits, dried, powdered or cooked vegetables. This is a research that addresses this way of living to act as a precaution towards making the food healthier. It is with a significant concentration in Kenyatta market than Kagochi while chromium’s level was higher in Kagochi compared to Kenyatta market. From the above figures of heavy metals, it was concluded that ...
Objective: To determine the noxious attribute of methanol extract of Nigeria bee propolis at 300 and 600 mg/kg body weight in rats. Methods: Healthy Wistar rats were indiscriminately assigned into three groups (A-C) of five rats each. The control rats (Group A) were orally given 0.5 mL of dimethyl sulfoxide daily for 21 days while rats in Groups B and C were administered the same 0.5 mL dimethyl sulfoxide containing 300 and 600 mg/kg body weight methanol extract of bee propolis respective...
Free radicals are highly reactive molecules generated during oxidation reactions which in turn initiate chain reactions resulting to cellular damage. There is substantial evidence implicating free radicals especially reactive oxygen species (ROS) in the etiology of more than one hundred degenerative disorders in humans including, arthritis, atherosclerosis, ischemia and reperfusion injury of many tissues, gastritis, diabetics, central nervous system injury, acquired immunodeficiency syndrome ...
Te study aims to determine the association of malaria infection with ABO blood groups and genotype and also to detect point mutations at positions 86, 184, 1034, and 1042 of the Plasmodium falciparum multidrug resistance gene (pfmdr1) in blood samples collected from pregnant women attending General Hospital Minna. Out of 250 pregnant women screened, 39 (15.60%) had malaria infection. Prevalence was higher in women, during the third trimester (46.15%), genotype AA (64.10%), and O blood group (...
Abstract The enhanced safe drug delivery properties of polyethylene glycol (PEG) – modified Diaminazene aceturate nanocomposite against Trypanosoma brucei infected rats were evaluated. The drug conjugation was carried out by adding gold nanoparticle to PEG and diminazene aceturate. A group of infected rats were treated with free diaminazene aceturate, while other groups were treated with conjugated drug at different drug release time interval. Results revealed complete parasite clear...
Abstract Disruption of electrolyte, redox and neurochemical homeostasis alongside cellular energy crisis is a hallmark of cerebral ischaemia and reperfusion injury. This study investigated the effect of kolaviron (KV) on cortical and striatal cation imbalance, oxidative stress and neurochemical disturbances as well as neurobehavioural deficits in animals subjected to bilateral common carotid artery occlusion (BCCAO)-induced ischaemia/reperfusion injury. KV was administered at a dose of 100...