EXTENDED ABSTRACT Worldwide, there is increased use of antimicrobial drugs due to the occurrence of diseases of human and animals. The general objective was to study the effect of cooking procedures and cold storage on the levels of Oxytetracycline (OTC) residues in beef in Tanzania. The study used a cross-sectional research design whereby both quantitative and qualitative data were collected from the Dodoma region, Tanzania. The household survey was conducted to assess knowledge, attitude ...
TABLE OF CONTENTSDECLARATION ........... ........................................................... .................... .. .............................. ... iAPPROVAL ........................................................................................ .................................. ......... iiDEDICATION ............... ......................................................................... ....................................... iiiACKNOWLEDGEMENT ........................ .........
ABSTRACT The gametocytocidal effect of antimalarial drugs has become important in malaria research owing to the global quest to eradicate the disease. In Ghana and most parts of Africa, people still depend on herbal medications despite advances in western medicine. However, these drugs lack the necessary scientific assessment. The IC50s of 10 known herbal antimalarial drugs on the Ghanaian market were determined. The development of sexual stages of the Plasmodium falciparum was monitored and ...
ABSTRACT The number one killer disease in the world is Cardiovascular Disease1 . The most serious element of Cardiovascular Disease is Coronary Artery Disease. Currently, the main treatment for Coronary Artery Disease is stent placement surgery. However, its long time safety and efficiency are the major setbacks, as it is associated with late restenosis and late thrombosis. These are set caused by the durable polymeric film used as the drug carrier. To improve on the current treatment (stent...
Background Tuberculosis is the highest cause of death in persons infected with HIV hence the need for prevention. The gold standard of self- administered isoniazid for 6 to 12 months is effective but adherence is poor and causes more adverse events. Rifapentine plus isoniazid for 3months administered under DOTS have limited treatment duration and may result in higher adherence and reduced adverse events. Objectives To determine the effectiveness of Rifapentine plus Isoniazid compared with i...
Abstract The physiological, biochemical and anaesthetic effects of the drug combinations were studies in West African Dwarf goat. In protocol I, there was a significant (p < 0.05) increase in the HR of GP I goats at 10 mins post-induction (PI), which significantly (p < 0.05) decreased from 30 min PI. The HR significantly decreased (p < 0.05) at 20 min in GP IV goats, and at 10 min GP II goats, and returned to the pre-anaesthetic value at 40 min PI. However, HR decreased significantly (p < 0...
TABLE OF CONTENTS DECLARATION ............................................................................................ i APPROVAL .................................................................................................. ii ACKNOWLEGEMENT ...............................................•..................................• iii DEDICATION ............................................................................................................... iv TABLE OF CONTENTS .............
ABSTRACT Drug treatment of malaria is being hampered by the emergence of drug resistant strains of malaria parasites. Rapid methods for monitoring patients' response to treatment, applicable to field conditions, would aid management and control of drug resistant P. falciparum infect ions. In this study, mutation specific polymerase chain reaction assays using 3'-mismatched oligonucleotide primers which annealed to the wild or mutated parasites gene encoding dihydrofolate reductase-thymidylat...
ABSTRACT Around 5.1% of the worldwide disease burden and injury, as well as 5.9% of all fatalities are linked to alcohol abuse. In Kenya, Kiambu County is one of the leading counties in alcohol abuse and alcohol-related physical injuries. The study established the types and management of alcohol-related physical injuries among 383 persons with alcohol use disorder in Githunguri Sub-county, Kiambu County. The crosssectional survey specifically occurred from March-November 2015 in Githiga and ...
TABLE OF CONTENT.Title page .............................................................................................. .Declaration.............................................................................................. 1Approval. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11Dedication............. . . . . . . . . . . . . . . . . . . . . . . ...
ABSTRACT Xylopic acid (XA), the major constituent of the fruit of Xylopia aethiopica has shown several pharmacological properties. Consequently, the fruit is being used in the preparation of food. Traditionally, the plant is used to treat several diseases and it has been formulated into a nasal drop despite the lack of information about its safety, food-drug interaction, and other pharmacokinetic properties. Therefore, this study investigated the antiplasmodial effect of XA on P. falciparum, ...
ABSTRACT Malaria is one of the world’s most common and serious diseases causing death up to about three million people each year. Its most severe occurrence is caused by the protozoan Plasmodium falciparum. Reports have shown that the resistance of the parasite to existing drugs is increasing. Therefore, there is a huge and urgent need to discover and validate new drug or vaccine targets to enable the development of new treatments for malaria. The ability to discover these drug or vaccine ...
ABSTRACT The highest number of new HIV infections in Zimbabwe are recorded in the 20-29 age group, with most being through heterosexual transmission. University students are a sub-population within this age group, and are key in HIV prevention efforts as they tend to engage in risky sexual behaviours. This study sought to determine the prevalence of high risk sexual behaviours among undergraduate university students at Midlands State University, and determine the predictive value of alcohol u...
ABSTRACT The study was a research on the socio economic problems and education of AIDS orphans in Mathira Division, Nyeri District, Central province of Kenya. The elements examined were Joverty, neglect, stigmatization and child abuse. the study used a sample survey designed, where a simple random sampling procedures was used to form a sample size of thirty (30) AIDS orphans and twenty six (26) AIDS orphans guardians, and twenty four (24) AIDS orphans teachers, interview schedules were the to...
ABSTRACT Invasive Non-Typhoidal Salmonella infections have become widespread in sub-Saharan Africa. Predominant hyper-virulent clone S. Typhimurium ST313 is found to be associated with bloodstream invasion and multidrug resistance. Despite its importance, limited information is available on the circulating genotypes causing invasive non-typhoidal salmonellosis in Ghana. A total of fifty-one NTS isolates from pediatric blood samples was used for this study. The resistance profiles of isolates...