ABSTRACT This research work focused on the use of an hybrid RANS-LES turbulence model in simulating and checking the drag performance characteristics of an aerodynamic vehicle. The Spalart-Allmaras shear stress transport (SST)- Scale Adaptive Simulation (SAS) Turbulence model was selected for use, and with the help of OpenFOAM Finite Volume Computational Fluid Dynamic Solver the simulation algorithm was set and carried out in a total time step of 4000. Convergence was achieved under the stip...
ABSTRACT This study set out to explore the student enrollment and selection of public day secondary schools in magumoni division, meru south district, Kenya" In this chapter the major findings of the study are discussed and interpreted. The discussion of the findings of the present research was based and centered on the major research objectives and questions directing the study. To determine the social and economic constraints /problems facing day secondary schools in Magumoni division...
ABSTRACT The research examined the experiences of children who have gone through the foster care program in Zimbabwe. Children coming into foster care would have been take away from their parents may be facing emotional, psychological and behavioural problems due to the turmoil, abuse and negligence they may have experienced as such it is critical to emphasise the healing aspect of foster care. There are certain challenges from the system which need to be addressed. This research was guided b...
ABSTRACT The study was to assess the impact of recreational activities on child delinquency at the Cape Coast Football for Hope Centre. Descriptive survey design and questionnaire was used to collect data from 140 respondents at the Football for Hope Centre. Data collected was analyzed using descriptive statistics (frequency and simple percentages based on research questions. Results revealed that neglect, poverty and abuse were the major causes of streetism in Cape Coast. Also, the major rea...
SUMMARY This study explored whether Namibian legal and allied criminal justice professionals involved in child sexual abuse investigations were cognizant of child suggestibility and whether the concept child suggestibility was duly weighted during investigations and court proceedings. The legal practitioners were defined as prosecutors, magistrates and private defense lawyers. It was hypothesized that the Namibian legal and allied criminal justice professionals involved in child sexual abuse...
ABSTRACT Domestic violence victims explore avenues within two major supporting systems, formal and informal, in their help-seeking processes for amicable resolutions or justice. Often, victims explore different avenues when seeking help until they achieve a satisfactory remedy. The core objective of the study was to explore the help-seeking trajectories of domestic violence victims. The data was collected at the Greater Accra regional office of the Domestic Violence and Victims‟ Support Un...
ABSTRACT White yam starch obtained from the tubers of Dioscorea rotundata Poir was modified by hydroxypropylation and used as a binding agent in a metronidazole tablet formulation and compared with corn starch BP. The quantitative effects of the novel starch binder on the mechanical (tensile strength and friability) and release properties (disintegration and dissolution times) of the metronidazole tablet was analyzed using a full 23 factorial experimental design. The individual and interactio...
Abstract This study was conducted to analyze the components of the plastic materials used in water and drug bottles by using laser induced breakdown spectroscopy (LIBS). Bottle samples were collected from some factories in Sudan, the samples were collected pre- and post-used. Samples were irradiated by Nd: YAG laser at 266 nm, repetition rate 2Hz, with pulse energy of 80mJ. The recorded spectra of the samples were analyzed using National Institute Standard and Technology (NIST) and Origin L...
ABSTRACT Eukaryotic pathogens are responsible for several serious human diseases, however, most drugs used as treatment regimens are ineffective while others still in use are toxic. This study seeks to identify bioactive molecules from wood decay fungal (WDF) extracts with activity against eukaryotic pathogens (especially Candida albicans and Plasmodium falciparum). The Saccharomyces cerevisiae model organism for eukaryotic cell biology studies is extensively used to screen bioactive molecul...
Abstract Background Sulfadoxine-pyrimethamine (SP) is the only anti-malarial drug formulation approved for intermittent preventive treatment in pregnancy (IPTp). However, mutations in the Plasmodium falciparum dhfr (Pfdhfr) and dhps (Pfdhps) genes confer resistance to pyrimethamine and sulfadoxine, respectively. Here, the frequencies of SP resistance-associated mutations from 2005 to 2018 were compared in samples from Kenyan children with malaria residing in a holoendemic transmission region...
ABSTRACT Background: A major constraint in the management of People Living with Human Immunodeficiency Virus, with highly active antiretroviral therapy is the high incidence of adverse drug reaction among patients. Nevirapine, a non-nucleoside reverse transcriptase inhibitor is among the first-line antiretroviral therapy used in Ghana for the management of Human immunodeficiency virus-1 patients. Despite its usefulness, hypersensitivity reaction is a common complication that accounts for p...
ABSTRACT The roots and seeds of Moringa oleifera were analysed for their nutritional, antinutritional and antimicrobial activities on Pseudomonas aeruginosa, Staphylococcus aureus, Proteus mirabilis, Streptococcus fecalis, Escherichia coli and Candida albicans. Quantitative phytochemical analysis showed the presence of 0.57% and 1.17% oxalates, 4.02% and 2.66% phytic acid, 1.92% and 3.99% alkaloid, 65.47 mg/100 g and 109.12 mg/100 g tanins for the roots and seeds respectively. Proximate a...
ABSTRACT There have been several reports on the antimicrobial activity of different herbal extracts. Medicinal plants are believed to be the best source for obtaining a variety of drugs. Hibiscus sabdariffa L. is a medicinal plant known for its nutritional delicacy and medicinal properties such as the treatment of diseases like hypertension, coughs, biliousness, boils and wounds. Currently, the main therapy for bacterial infections is the use of synthetic antibiotics. However, the misuse and...
ABSTRACT Management of diabetes mellitus using conventional drugs is either unaffordable, unavailable or has undesirable side effects. Medicinal plants such as Zanthoxylum chalybeum (Rutaceae) have found prominence in management of diabetes and previous studies showed the efficacies of aqueous root and stem bark against in vivo alloxan and streptozotocin–induced diabetes in rats. However, the phytochemical evidence for these activities was never established. Therefore, this study was to est...
Plasmodium is a genus of parasitic protozoa, many of which cause malaria in their host. Five species namely; P. falciparum, P. malarae, P. ovale, P. vivax and P. knowlesi cause human malaria. Malaria due to P. falciparum is one of the most severe public health problems worldwide with an annual estimated 207 million clinical episodes and 627,000 deaths. The use of conventional antimalarial drugs as treatment for malaria is greatly hindered by drug resistance exhibited by the parasite. Conseque...